The activating effect of dietary protein on linoleic acid desaturation

Autores
Peluffo, Raúl Omar; Tacconi de Gómez Dumm, Irma Nelva; Brenner, Rodolfo Roberto
Año de publicación
1972
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The desaturation of14C-1-linoleic acid to γ-linolenic acid and their incorporation into the microsomal lipids of rats fed on a balanced diet and a protein diet were measured in vitro. It was shown that a protein diet does not change significantly the distribution of the radioactivity among the different lipidic fractions compared to the animals fed on a balanced diet. However the microsomal desaturation of linoleic acid to γ-linolenic acid increased in the rats maintained on a protein diet. Besides, the amount and composition of the free fatty acids present in the microsomes of the animals fed on both diets were similar enough to discard the hypothesis that they may modify the desaturation of linoleic acid produced by the diet. The enzymic activity of the linoleyl desaturase of liver microsomes of animals fed on a protein diet, measured in substrate saturating conditions, is greater than in animals with balanced diet. Consequently the results support the hypothesis that a protein diet increases specifically the desaturating activity of the microsomes.
Facultad de Ciencias Medicas
Materia
Ciencias Exactas
Medicina
γ-linolenic acid
14C-l-linoleic acid
microsomes
diet
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/141539
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/141539
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling The activating effect of dietary protein on linoleic acid desaturationPeluffo, Raúl OmarTacconi de Gómez Dumm, Irma NelvaBrenner, Rodolfo RobertoCiencias ExactasMedicinaγ-linolenic acid14C-l-linoleic acidmicrosomesdietThe desaturation of14C-1-linoleic acid to γ-linolenic acid and their incorporation into the microsomal lipids of rats fed on a balanced diet and a protein diet were measured in vitro. It was shown that a protein diet does not change significantly the distribution of the radioactivity among the different lipidic fractions compared to the animals fed on a balanced diet. However the microsomal desaturation of linoleic acid to γ-linolenic acid increased in the rats maintained on a protein diet. Besides, the amount and composition of the free fatty acids present in the microsomes of the animals fed on both diets were similar enough to discard the hypothesis that they may modify the desaturation of linoleic acid produced by the diet. The enzymic activity of the linoleyl desaturase of liver microsomes of animals fed on a protein diet, measured in substrate saturating conditions, is greater than in animals with balanced diet. Consequently the results support the hypothesis that a protein diet increases specifically the desaturating activity of the microsomes.Facultad de Ciencias Medicas1972info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf363-367http://sedici.unlp.edu.ar/handle/10915/141539enginfo:eu-repo/semantics/altIdentifier/issn/0024-4201info:eu-repo/semantics/altIdentifier/issn/1558-9307info:eu-repo/semantics/altIdentifier/doi/10.1007/bf02531504info:eu-repo/semantics/altIdentifier/pmid/5038492info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:32:11Zoai:sedici.unlp.edu.ar:10915/141539Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:32:12.254SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv The activating effect of dietary protein on linoleic acid desaturation
title The activating effect of dietary protein on linoleic acid desaturation
spellingShingle The activating effect of dietary protein on linoleic acid desaturation
Peluffo, Raúl Omar
Ciencias Exactas
Medicina
γ-linolenic acid
14C-l-linoleic acid
microsomes
diet
title_short The activating effect of dietary protein on linoleic acid desaturation
title_full The activating effect of dietary protein on linoleic acid desaturation
title_fullStr The activating effect of dietary protein on linoleic acid desaturation
title_full_unstemmed The activating effect of dietary protein on linoleic acid desaturation
title_sort The activating effect of dietary protein on linoleic acid desaturation
dc.creator.none.fl_str_mv Peluffo, Raúl Omar
Tacconi de Gómez Dumm, Irma Nelva
Brenner, Rodolfo Roberto
author Peluffo, Raúl Omar
author_facet Peluffo, Raúl Omar
Tacconi de Gómez Dumm, Irma Nelva
Brenner, Rodolfo Roberto
author_role author
author2 Tacconi de Gómez Dumm, Irma Nelva
Brenner, Rodolfo Roberto
author2_role author
author
dc.subject.none.fl_str_mv Ciencias Exactas
Medicina
γ-linolenic acid
14C-l-linoleic acid
microsomes
diet
topic Ciencias Exactas
Medicina
γ-linolenic acid
14C-l-linoleic acid
microsomes
diet
dc.description.none.fl_txt_mv The desaturation of14C-1-linoleic acid to γ-linolenic acid and their incorporation into the microsomal lipids of rats fed on a balanced diet and a protein diet were measured in vitro. It was shown that a protein diet does not change significantly the distribution of the radioactivity among the different lipidic fractions compared to the animals fed on a balanced diet. However the microsomal desaturation of linoleic acid to γ-linolenic acid increased in the rats maintained on a protein diet. Besides, the amount and composition of the free fatty acids present in the microsomes of the animals fed on both diets were similar enough to discard the hypothesis that they may modify the desaturation of linoleic acid produced by the diet. The enzymic activity of the linoleyl desaturase of liver microsomes of animals fed on a protein diet, measured in substrate saturating conditions, is greater than in animals with balanced diet. Consequently the results support the hypothesis that a protein diet increases specifically the desaturating activity of the microsomes.
Facultad de Ciencias Medicas
description The desaturation of14C-1-linoleic acid to γ-linolenic acid and their incorporation into the microsomal lipids of rats fed on a balanced diet and a protein diet were measured in vitro. It was shown that a protein diet does not change significantly the distribution of the radioactivity among the different lipidic fractions compared to the animals fed on a balanced diet. However the microsomal desaturation of linoleic acid to γ-linolenic acid increased in the rats maintained on a protein diet. Besides, the amount and composition of the free fatty acids present in the microsomes of the animals fed on both diets were similar enough to discard the hypothesis that they may modify the desaturation of linoleic acid produced by the diet. The enzymic activity of the linoleyl desaturase of liver microsomes of animals fed on a protein diet, measured in substrate saturating conditions, is greater than in animals with balanced diet. Consequently the results support the hypothesis that a protein diet increases specifically the desaturating activity of the microsomes.
publishDate 1972
dc.date.none.fl_str_mv 1972
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/141539
url http://sedici.unlp.edu.ar/handle/10915/141539
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/0024-4201
info:eu-repo/semantics/altIdentifier/issn/1558-9307
info:eu-repo/semantics/altIdentifier/doi/10.1007/bf02531504
info:eu-repo/semantics/altIdentifier/pmid/5038492
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
363-367
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.070432

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