Conjugated linoleic acid and fatty acid binding protein as antioxidants

Autores
Piergiacomi, Viviana Angélica; Palacios, Alejandro
Año de publicación
2006
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Studies were carried out to determine the effect of conjugated linoleic acid (CLA) and rat liver cytosolic protein enriched in fatty acid binding protein (FABP) on the non-enzymatic lipid peroxidation of rat liver microsomes. The inhibition of lipid peroxidation was more evident when the FABP containing fraction obtained from CLA-group was used with either kind of microsomes (CLA and control). The chemiluminescence and polyunsaturated fatty acid composition of rat liver microsomes changed after CLA treatment. When native and peroxidized microsomes obtained from control group were compared, the most affected polyunsaturated fatty acids were: C18:2, C18:3 and C20:4, while in CLA-group C20:4 was mainly peroxidized The simultaneous analysis of chemiluminescence and fatty acid composition demonstrated that CLA and FABP play a role protecting rat liver microsomes against the harmful effect of lipid peroxidation.
Facultad de Ciencias Veterinarias
Materia
Ciencias Veterinarias
Conjugated linoleic acid
Fatty acid binding protein
Lipid peroxidation
Liver
Microsomes
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-nd/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/107536

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network_name_str SEDICI (UNLP)
spelling Conjugated linoleic acid and fatty acid binding protein as antioxidantsPiergiacomi, Viviana AngélicaPalacios, AlejandroCiencias VeterinariasConjugated linoleic acidFatty acid binding proteinLipid peroxidationLiverMicrosomesStudies were carried out to determine the effect of conjugated linoleic acid (CLA) and rat liver cytosolic protein enriched in fatty acid binding protein (FABP) on the non-enzymatic lipid peroxidation of rat liver microsomes. The inhibition of lipid peroxidation was more evident when the FABP containing fraction obtained from CLA-group was used with either kind of microsomes (CLA and control). The chemiluminescence and polyunsaturated fatty acid composition of rat liver microsomes changed after CLA treatment. When native and peroxidized microsomes obtained from control group were compared, the most affected polyunsaturated fatty acids were: C18:2, C18:3 and C20:4, while in CLA-group C20:4 was mainly peroxidized The simultaneous analysis of chemiluminescence and fatty acid composition demonstrated that CLA and FABP play a role protecting rat liver microsomes against the harmful effect of lipid peroxidation.Facultad de Ciencias Veterinarias2006info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf139-148http://sedici.unlp.edu.ar/handle/10915/107536enginfo:eu-repo/semantics/altIdentifier/url/http://www.fvet.uba.ar/fcvanterior/publicaciones/archivos/Volumen8N1/piergiacomi8.pdfinfo:eu-repo/semantics/altIdentifier/issn/1668-3498info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-10-15T11:15:56Zoai:sedici.unlp.edu.ar:10915/107536Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-10-15 11:15:56.773SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Conjugated linoleic acid and fatty acid binding protein as antioxidants
title Conjugated linoleic acid and fatty acid binding protein as antioxidants
spellingShingle Conjugated linoleic acid and fatty acid binding protein as antioxidants
Piergiacomi, Viviana Angélica
Ciencias Veterinarias
Conjugated linoleic acid
Fatty acid binding protein
Lipid peroxidation
Liver
Microsomes
title_short Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_full Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_fullStr Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_full_unstemmed Conjugated linoleic acid and fatty acid binding protein as antioxidants
title_sort Conjugated linoleic acid and fatty acid binding protein as antioxidants
dc.creator.none.fl_str_mv Piergiacomi, Viviana Angélica
Palacios, Alejandro
author Piergiacomi, Viviana Angélica
author_facet Piergiacomi, Viviana Angélica
Palacios, Alejandro
author_role author
author2 Palacios, Alejandro
author2_role author
dc.subject.none.fl_str_mv Ciencias Veterinarias
Conjugated linoleic acid
Fatty acid binding protein
Lipid peroxidation
Liver
Microsomes
topic Ciencias Veterinarias
Conjugated linoleic acid
Fatty acid binding protein
Lipid peroxidation
Liver
Microsomes
dc.description.none.fl_txt_mv Studies were carried out to determine the effect of conjugated linoleic acid (CLA) and rat liver cytosolic protein enriched in fatty acid binding protein (FABP) on the non-enzymatic lipid peroxidation of rat liver microsomes. The inhibition of lipid peroxidation was more evident when the FABP containing fraction obtained from CLA-group was used with either kind of microsomes (CLA and control). The chemiluminescence and polyunsaturated fatty acid composition of rat liver microsomes changed after CLA treatment. When native and peroxidized microsomes obtained from control group were compared, the most affected polyunsaturated fatty acids were: C18:2, C18:3 and C20:4, while in CLA-group C20:4 was mainly peroxidized The simultaneous analysis of chemiluminescence and fatty acid composition demonstrated that CLA and FABP play a role protecting rat liver microsomes against the harmful effect of lipid peroxidation.
Facultad de Ciencias Veterinarias
description Studies were carried out to determine the effect of conjugated linoleic acid (CLA) and rat liver cytosolic protein enriched in fatty acid binding protein (FABP) on the non-enzymatic lipid peroxidation of rat liver microsomes. The inhibition of lipid peroxidation was more evident when the FABP containing fraction obtained from CLA-group was used with either kind of microsomes (CLA and control). The chemiluminescence and polyunsaturated fatty acid composition of rat liver microsomes changed after CLA treatment. When native and peroxidized microsomes obtained from control group were compared, the most affected polyunsaturated fatty acids were: C18:2, C18:3 and C20:4, while in CLA-group C20:4 was mainly peroxidized The simultaneous analysis of chemiluminescence and fatty acid composition demonstrated that CLA and FABP play a role protecting rat liver microsomes against the harmful effect of lipid peroxidation.
publishDate 2006
dc.date.none.fl_str_mv 2006
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/107536
url http://sedici.unlp.edu.ar/handle/10915/107536
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.fvet.uba.ar/fcvanterior/publicaciones/archivos/Volumen8N1/piergiacomi8.pdf
info:eu-repo/semantics/altIdentifier/issn/1668-3498
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.format.none.fl_str_mv application/pdf
139-148
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
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instname_str Universidad Nacional de La Plata
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institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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