Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina

Autores
Michlig, Nicolás; Signorini, Marcelo; Gaggiotti, Mónica del Carmen; Chiericatti, Carolina Andrea Antonia; Basilico, Juan Carlos; Repetti, María Rosa; Beldomenico, Horacio Ramon
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The objectives of this study were to assess aflatoxin M1 (AFM1) contamination in bulk tank milk, and to further identify the risk factors associated with the presence of AFM1 in raw milk in Argentina. The presence of AFM1 was investigated in 160 bulk tank milk samples collected from farms located in the most important milk production region in Argentina during one year (four seasons). Samples wereanalysed using immunoaffinity column (IAC) cleanup and UHPLC-MS/MS method for determining AFM1 at low levels of concentrations (LOQ ¼ 0.003 mg L1). A survey about the potential factors associated with the presence of AFM1 in milk was performed directly in the field through a questionnaire applied to the farmers. Chi-square and logistic regression were performed with presence of AFM1 in milk as dependent variable, and potential risk factors as independent variables. Incidence of AFM1 in raw milk was 38.8% and, in all samples, AFM1 levels were lower than the Southern Common Market (MERCOSUR) Regulation (maximum level accepted ¼ 0.5 mg L1). Commercial feed consumption (OR ¼ 4.630, P ¼ 0.001), soybean expeller consumption (>0.95 kgDM/cow) (OR ¼ 3.542, P ¼ 0.019), and cotton seed consumption (>1.5 kgDM/cow) (OR ¼ 2.949, P ¼ 0.089) were associated with the incidence of AFM1 in raw milk. Despite the incidence and the level of AFM1 in milk produced and commercialized in Argentina is not a serious problem for public health. The farm breeding intensification and the supplementation with commercial feed, soybean expeller, and cotton seed seems to be the risk factors that impacts on the AFM1 milk contamination. Therefore, Argentina should improve its monitoring program on mycotoxins in animal feed and milk and improve the management practices in farms.
Fil: Michlig, Nicolás. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Gaggiotti, Mónica del Carmen. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Chiericatti, Carolina Andrea Antonia. Universidad Nacional del Litoral. Facultad de Ingeniería Química; Argentina
Fil: Basilico, Juan Carlos. Universidad Nacional del Litoral. Facultad de Ingeniería Química; Argentina
Fil: Repetti, María Rosa. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; Argentina
Fil: Beldomenico, Horacio Ramon. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; Argentina
Materia
AFLATOXIN M1
MILK
RISK FACTORS
UHPLC-MS/MS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/111236
Acceder
id CONICETDig_d183507eca20562011f7a98ad8f543bb
oai_identifier_str oai:ri.conicet.gov.ar:11336/111236
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from ArgentinaMichlig, NicolásSignorini, MarceloGaggiotti, Mónica del CarmenChiericatti, Carolina Andrea AntoniaBasilico, Juan CarlosRepetti, María RosaBeldomenico, Horacio RamonAFLATOXIN M1MILKRISK FACTORSUHPLC-MS/MShttps://purl.org/becyt/ford/4.2https://purl.org/becyt/ford/4The objectives of this study were to assess aflatoxin M1 (AFM1) contamination in bulk tank milk, and to further identify the risk factors associated with the presence of AFM1 in raw milk in Argentina. The presence of AFM1 was investigated in 160 bulk tank milk samples collected from farms located in the most important milk production region in Argentina during one year (four seasons). Samples wereanalysed using immunoaffinity column (IAC) cleanup and UHPLC-MS/MS method for determining AFM1 at low levels of concentrations (LOQ ¼ 0.003 mg L1). A survey about the potential factors associated with the presence of AFM1 in milk was performed directly in the field through a questionnaire applied to the farmers. Chi-square and logistic regression were performed with presence of AFM1 in milk as dependent variable, and potential risk factors as independent variables. Incidence of AFM1 in raw milk was 38.8% and, in all samples, AFM1 levels were lower than the Southern Common Market (MERCOSUR) Regulation (maximum level accepted ¼ 0.5 mg L1). Commercial feed consumption (OR ¼ 4.630, P ¼ 0.001), soybean expeller consumption (>0.95 kgDM/cow) (OR ¼ 3.542, P ¼ 0.019), and cotton seed consumption (>1.5 kgDM/cow) (OR ¼ 2.949, P ¼ 0.089) were associated with the incidence of AFM1 in raw milk. Despite the incidence and the level of AFM1 in milk produced and commercialized in Argentina is not a serious problem for public health. The farm breeding intensification and the supplementation with commercial feed, soybean expeller, and cotton seed seems to be the risk factors that impacts on the AFM1 milk contamination. Therefore, Argentina should improve its monitoring program on mycotoxins in animal feed and milk and improve the management practices in farms.Fil: Michlig, Nicolás. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; ArgentinaFil: Gaggiotti, Mónica del Carmen. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; ArgentinaFil: Chiericatti, Carolina Andrea Antonia. Universidad Nacional del Litoral. Facultad de Ingeniería Química; ArgentinaFil: Basilico, Juan Carlos. Universidad Nacional del Litoral. Facultad de Ingeniería Química; ArgentinaFil: Repetti, María Rosa. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; ArgentinaFil: Beldomenico, Horacio Ramon. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; ArgentinaElsevier2016-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/111236Michlig, Nicolás; Signorini, Marcelo; Gaggiotti, Mónica del Carmen; Chiericatti, Carolina Andrea Antonia; Basilico, Juan Carlos; et al.; Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina; Elsevier; Food Control; 64; 6-2016; 151-1560956-7135CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.foodcont.2015.12.025info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:51:30Zoai:ri.conicet.gov.ar:11336/111236instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:51:30.276CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
spellingShingle Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
Michlig, Nicolás
AFLATOXIN M1
MILK
RISK FACTORS
UHPLC-MS/MS
title_short Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title_full Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title_fullStr Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title_full_unstemmed Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title_sort Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
dc.creator.none.fl_str_mv Michlig, Nicolás
Signorini, Marcelo
Gaggiotti, Mónica del Carmen
Chiericatti, Carolina Andrea Antonia
Basilico, Juan Carlos
Repetti, María Rosa
Beldomenico, Horacio Ramon
author Michlig, Nicolás
author_facet Michlig, Nicolás
Signorini, Marcelo
Gaggiotti, Mónica del Carmen
Chiericatti, Carolina Andrea Antonia
Basilico, Juan Carlos
Repetti, María Rosa
Beldomenico, Horacio Ramon
author_role author
author2 Signorini, Marcelo
Gaggiotti, Mónica del Carmen
Chiericatti, Carolina Andrea Antonia
Basilico, Juan Carlos
Repetti, María Rosa
Beldomenico, Horacio Ramon
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv AFLATOXIN M1
MILK
RISK FACTORS
UHPLC-MS/MS
topic AFLATOXIN M1
MILK
RISK FACTORS
UHPLC-MS/MS
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.2
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv The objectives of this study were to assess aflatoxin M1 (AFM1) contamination in bulk tank milk, and to further identify the risk factors associated with the presence of AFM1 in raw milk in Argentina. The presence of AFM1 was investigated in 160 bulk tank milk samples collected from farms located in the most important milk production region in Argentina during one year (four seasons). Samples wereanalysed using immunoaffinity column (IAC) cleanup and UHPLC-MS/MS method for determining AFM1 at low levels of concentrations (LOQ ¼ 0.003 mg L1). A survey about the potential factors associated with the presence of AFM1 in milk was performed directly in the field through a questionnaire applied to the farmers. Chi-square and logistic regression were performed with presence of AFM1 in milk as dependent variable, and potential risk factors as independent variables. Incidence of AFM1 in raw milk was 38.8% and, in all samples, AFM1 levels were lower than the Southern Common Market (MERCOSUR) Regulation (maximum level accepted ¼ 0.5 mg L1). Commercial feed consumption (OR ¼ 4.630, P ¼ 0.001), soybean expeller consumption (>0.95 kgDM/cow) (OR ¼ 3.542, P ¼ 0.019), and cotton seed consumption (>1.5 kgDM/cow) (OR ¼ 2.949, P ¼ 0.089) were associated with the incidence of AFM1 in raw milk. Despite the incidence and the level of AFM1 in milk produced and commercialized in Argentina is not a serious problem for public health. The farm breeding intensification and the supplementation with commercial feed, soybean expeller, and cotton seed seems to be the risk factors that impacts on the AFM1 milk contamination. Therefore, Argentina should improve its monitoring program on mycotoxins in animal feed and milk and improve the management practices in farms.
Fil: Michlig, Nicolás. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Gaggiotti, Mónica del Carmen. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Chiericatti, Carolina Andrea Antonia. Universidad Nacional del Litoral. Facultad de Ingeniería Química; Argentina
Fil: Basilico, Juan Carlos. Universidad Nacional del Litoral. Facultad de Ingeniería Química; Argentina
Fil: Repetti, María Rosa. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; Argentina
Fil: Beldomenico, Horacio Ramon. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos; Argentina
description The objectives of this study were to assess aflatoxin M1 (AFM1) contamination in bulk tank milk, and to further identify the risk factors associated with the presence of AFM1 in raw milk in Argentina. The presence of AFM1 was investigated in 160 bulk tank milk samples collected from farms located in the most important milk production region in Argentina during one year (four seasons). Samples wereanalysed using immunoaffinity column (IAC) cleanup and UHPLC-MS/MS method for determining AFM1 at low levels of concentrations (LOQ ¼ 0.003 mg L1). A survey about the potential factors associated with the presence of AFM1 in milk was performed directly in the field through a questionnaire applied to the farmers. Chi-square and logistic regression were performed with presence of AFM1 in milk as dependent variable, and potential risk factors as independent variables. Incidence of AFM1 in raw milk was 38.8% and, in all samples, AFM1 levels were lower than the Southern Common Market (MERCOSUR) Regulation (maximum level accepted ¼ 0.5 mg L1). Commercial feed consumption (OR ¼ 4.630, P ¼ 0.001), soybean expeller consumption (>0.95 kgDM/cow) (OR ¼ 3.542, P ¼ 0.019), and cotton seed consumption (>1.5 kgDM/cow) (OR ¼ 2.949, P ¼ 0.089) were associated with the incidence of AFM1 in raw milk. Despite the incidence and the level of AFM1 in milk produced and commercialized in Argentina is not a serious problem for public health. The farm breeding intensification and the supplementation with commercial feed, soybean expeller, and cotton seed seems to be the risk factors that impacts on the AFM1 milk contamination. Therefore, Argentina should improve its monitoring program on mycotoxins in animal feed and milk and improve the management practices in farms.
publishDate 2016
dc.date.none.fl_str_mv 2016-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/111236
Michlig, Nicolás; Signorini, Marcelo; Gaggiotti, Mónica del Carmen; Chiericatti, Carolina Andrea Antonia; Basilico, Juan Carlos; et al.; Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina; Elsevier; Food Control; 64; 6-2016; 151-156
0956-7135
CONICET Digital
CONICET
url http://hdl.handle.net/11336/111236
identifier_str_mv Michlig, Nicolás; Signorini, Marcelo; Gaggiotti, Mónica del Carmen; Chiericatti, Carolina Andrea Antonia; Basilico, Juan Carlos; et al.; Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina; Elsevier; Food Control; 64; 6-2016; 151-156
0956-7135
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.foodcont.2015.12.025
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269097828548608
score 13.13397

Publicaciones similares