Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina

Autores
Michlig, Nicolás; Signorini, Marcelo; Gaggiotti, Monica Del Carmen; Chiericatti, Carolina; Basílico, Juan Carlos; Repetti, María Rosa; Beldoménico, Horacio Ramón
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The objectives of this study were to assess aflatoxin M1 (AFM1) contamination in bulk tank milk, and to further identify the risk factors associated with the presence of AFM1 in raw milk in Argentina. The presence of AFM1 was investigated in 160 bulk tank milk samples collected from farms located in the most important milk production region in Argentina during one year (four seasons). Samples were analysed using immunoaffinity column (IAC) cleanup and UHPLC-MS/MS method for determining AFM1 at low levels of concentrations (LOQ = 0.003 μg L−1). A survey about the potential factors associated with the presence of AFM1 in milk was performed directly in the field through a questionnaire applied to the farmers. Chi-square and logistic regression were performed with presence of AFM1 in milk as dependent variable, and potential risk factors as independent variables. Incidence of AFM1 in raw milk was 38.8% and, in all samples, AFM1 levels were lower than the Southern Common Market (MERCOSUR) Regulation (maximum level accepted = 0.5 μg L−1). Commercial feed consumption (OR = 4.630, P = 0.001), soybean expeller consumption (>0.95 kgDM/cow) (OR = 3.542, P = 0.019), and cotton seed consumption (>1.5 kgDM/cow) (OR = 2.949, P = 0.089) were associated with the incidence of AFM1 in raw milk. Despite the incidence and the level of AFM1 in milk produced and commercialized in Argentina is not a serious problem for public health. The farm breeding intensification and the supplementation with commercial feed, soybean expeller, and cotton seed seems to be the risk factors that impacts on the AFM1 milk contamination. Therefore, Argentina should improve its monitoring program on mycotoxins in animal feed and milk and improve the management practices in farms.
EEA Rafaela
Fil: Michlig, Nicolás. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); Argentina
Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Gaggiotti, Monica Del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Chiericatti, C. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Laboratorio; Argentina
Fil: Basílico, J.C. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Laboratorio; Argentina
Fil: Repetti, María Rosa. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); Argentina
Fil: Beldoménico, Horacio Ramón. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); Argentina
Fuente
Food control 64 : 151-156. (June 2016)
Materia
Aflatoxinas
Leche Cruda
Almacenamiento a Granel
Factores de Riesgo
Aflatoxins
Raw Milk
Bulk Storage
Risk Factors
Argentina
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/2524
Acceder
id INTADig_218da8135fc917f61569fe900800721a
oai_identifier_str oai:localhost:20.500.12123/2524
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from ArgentinaMichlig, NicolásSignorini, MarceloGaggiotti, Monica Del CarmenChiericatti, CarolinaBasílico, Juan CarlosRepetti, María RosaBeldoménico, Horacio RamónAflatoxinasLeche CrudaAlmacenamiento a GranelFactores de RiesgoAflatoxinsRaw MilkBulk StorageRisk FactorsArgentinaThe objectives of this study were to assess aflatoxin M1 (AFM1) contamination in bulk tank milk, and to further identify the risk factors associated with the presence of AFM1 in raw milk in Argentina. The presence of AFM1 was investigated in 160 bulk tank milk samples collected from farms located in the most important milk production region in Argentina during one year (four seasons). Samples were analysed using immunoaffinity column (IAC) cleanup and UHPLC-MS/MS method for determining AFM1 at low levels of concentrations (LOQ = 0.003 μg L−1). A survey about the potential factors associated with the presence of AFM1 in milk was performed directly in the field through a questionnaire applied to the farmers. Chi-square and logistic regression were performed with presence of AFM1 in milk as dependent variable, and potential risk factors as independent variables. Incidence of AFM1 in raw milk was 38.8% and, in all samples, AFM1 levels were lower than the Southern Common Market (MERCOSUR) Regulation (maximum level accepted = 0.5 μg L−1). Commercial feed consumption (OR = 4.630, P = 0.001), soybean expeller consumption (>0.95 kgDM/cow) (OR = 3.542, P = 0.019), and cotton seed consumption (>1.5 kgDM/cow) (OR = 2.949, P = 0.089) were associated with the incidence of AFM1 in raw milk. Despite the incidence and the level of AFM1 in milk produced and commercialized in Argentina is not a serious problem for public health. The farm breeding intensification and the supplementation with commercial feed, soybean expeller, and cotton seed seems to be the risk factors that impacts on the AFM1 milk contamination. Therefore, Argentina should improve its monitoring program on mycotoxins in animal feed and milk and improve the management practices in farms.EEA RafaelaFil: Michlig, Nicolás. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); ArgentinaFil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Gaggiotti, Monica Del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; ArgentinaFil: Chiericatti, C. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Laboratorio; ArgentinaFil: Basílico, J.C. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Laboratorio; ArgentinaFil: Repetti, María Rosa. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); ArgentinaFil: Beldoménico, Horacio Ramón. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); Argentina2018-05-31T12:46:25Z2018-05-31T12:46:25Z2016-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://www.sciencedirect.com/science/article/pii/S0956713515303212http://hdl.handle.net/20.500.12123/25240956-7135https://doi.org/10.1016/j.foodcont.2015.12.025Food control 64 : 151-156. (June 2016)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-09-04T09:47:18Zoai:localhost:20.500.12123/2524instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:47:19.442INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
spellingShingle Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
Michlig, Nicolás
Aflatoxinas
Leche Cruda
Almacenamiento a Granel
Factores de Riesgo
Aflatoxins
Raw Milk
Bulk Storage
Risk Factors
Argentina
title_short Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title_full Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title_fullStr Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title_full_unstemmed Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
title_sort Risk factors associated with the presence of aflatoxin M1 in raw bulk milk from Argentina
dc.creator.none.fl_str_mv Michlig, Nicolás
Signorini, Marcelo
Gaggiotti, Monica Del Carmen
Chiericatti, Carolina
Basílico, Juan Carlos
Repetti, María Rosa
Beldoménico, Horacio Ramón
author Michlig, Nicolás
author_facet Michlig, Nicolás
Signorini, Marcelo
Gaggiotti, Monica Del Carmen
Chiericatti, Carolina
Basílico, Juan Carlos
Repetti, María Rosa
Beldoménico, Horacio Ramón
author_role author
author2 Signorini, Marcelo
Gaggiotti, Monica Del Carmen
Chiericatti, Carolina
Basílico, Juan Carlos
Repetti, María Rosa
Beldoménico, Horacio Ramón
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Aflatoxinas
Leche Cruda
Almacenamiento a Granel
Factores de Riesgo
Aflatoxins
Raw Milk
Bulk Storage
Risk Factors
Argentina
topic Aflatoxinas
Leche Cruda
Almacenamiento a Granel
Factores de Riesgo
Aflatoxins
Raw Milk
Bulk Storage
Risk Factors
Argentina
dc.description.none.fl_txt_mv The objectives of this study were to assess aflatoxin M1 (AFM1) contamination in bulk tank milk, and to further identify the risk factors associated with the presence of AFM1 in raw milk in Argentina. The presence of AFM1 was investigated in 160 bulk tank milk samples collected from farms located in the most important milk production region in Argentina during one year (four seasons). Samples were analysed using immunoaffinity column (IAC) cleanup and UHPLC-MS/MS method for determining AFM1 at low levels of concentrations (LOQ = 0.003 μg L−1). A survey about the potential factors associated with the presence of AFM1 in milk was performed directly in the field through a questionnaire applied to the farmers. Chi-square and logistic regression were performed with presence of AFM1 in milk as dependent variable, and potential risk factors as independent variables. Incidence of AFM1 in raw milk was 38.8% and, in all samples, AFM1 levels were lower than the Southern Common Market (MERCOSUR) Regulation (maximum level accepted = 0.5 μg L−1). Commercial feed consumption (OR = 4.630, P = 0.001), soybean expeller consumption (>0.95 kgDM/cow) (OR = 3.542, P = 0.019), and cotton seed consumption (>1.5 kgDM/cow) (OR = 2.949, P = 0.089) were associated with the incidence of AFM1 in raw milk. Despite the incidence and the level of AFM1 in milk produced and commercialized in Argentina is not a serious problem for public health. The farm breeding intensification and the supplementation with commercial feed, soybean expeller, and cotton seed seems to be the risk factors that impacts on the AFM1 milk contamination. Therefore, Argentina should improve its monitoring program on mycotoxins in animal feed and milk and improve the management practices in farms.
EEA Rafaela
Fil: Michlig, Nicolás. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); Argentina
Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
Fil: Gaggiotti, Monica Del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Chiericatti, C. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Laboratorio; Argentina
Fil: Basílico, J.C. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Laboratorio; Argentina
Fil: Repetti, María Rosa. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); Argentina
Fil: Beldoménico, Horacio Ramón. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Programa de Investigación y Análisis de Residuos y Contaminantes Químicos (PRINARC); Argentina
description The objectives of this study were to assess aflatoxin M1 (AFM1) contamination in bulk tank milk, and to further identify the risk factors associated with the presence of AFM1 in raw milk in Argentina. The presence of AFM1 was investigated in 160 bulk tank milk samples collected from farms located in the most important milk production region in Argentina during one year (four seasons). Samples were analysed using immunoaffinity column (IAC) cleanup and UHPLC-MS/MS method for determining AFM1 at low levels of concentrations (LOQ = 0.003 μg L−1). A survey about the potential factors associated with the presence of AFM1 in milk was performed directly in the field through a questionnaire applied to the farmers. Chi-square and logistic regression were performed with presence of AFM1 in milk as dependent variable, and potential risk factors as independent variables. Incidence of AFM1 in raw milk was 38.8% and, in all samples, AFM1 levels were lower than the Southern Common Market (MERCOSUR) Regulation (maximum level accepted = 0.5 μg L−1). Commercial feed consumption (OR = 4.630, P = 0.001), soybean expeller consumption (>0.95 kgDM/cow) (OR = 3.542, P = 0.019), and cotton seed consumption (>1.5 kgDM/cow) (OR = 2.949, P = 0.089) were associated with the incidence of AFM1 in raw milk. Despite the incidence and the level of AFM1 in milk produced and commercialized in Argentina is not a serious problem for public health. The farm breeding intensification and the supplementation with commercial feed, soybean expeller, and cotton seed seems to be the risk factors that impacts on the AFM1 milk contamination. Therefore, Argentina should improve its monitoring program on mycotoxins in animal feed and milk and improve the management practices in farms.
publishDate 2016
dc.date.none.fl_str_mv 2016-06
2018-05-31T12:46:25Z
2018-05-31T12:46:25Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://www.sciencedirect.com/science/article/pii/S0956713515303212
http://hdl.handle.net/20.500.12123/2524
0956-7135
https://doi.org/10.1016/j.foodcont.2015.12.025
url https://www.sciencedirect.com/science/article/pii/S0956713515303212
http://hdl.handle.net/20.500.12123/2524
https://doi.org/10.1016/j.foodcont.2015.12.025
identifier_str_mv 0956-7135
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Food control 64 : 151-156. (June 2016)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
_version_ 1842341355195465728
score 12.623145

Publicaciones similares