Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives

Autores
de Achaval, Delfina; Costanzo, Elsa Y.; Villarreal, Mirta Fabiana; Jáuregui, Ignacio Oscar; Chiodi, Araceli; Castro, Mariana Nair; Fahrer, Rodolfo D.; Leiguarda, Ramón C.; Chu, Elvina; Guinjoan, Salvador Martín
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Previous studies have suggested that social cognition is affected in individuals with schizophrenia. The purpose of this study was to explore to what extent social cognition deficits are shared by unaffected first-degree relatives, and the nature of the relationship between performance in different paradigms of social cognition. 20 Schizophrenia patients (7 females, 31 ± 10 years), 20 healthy age- and gender-matched individuals, 20 unaffected first-degree relatives of the schizophrenia patients (11 females, 50 ± 20 years), and 20 healthy individuals matched for age and gender were recruited. Patients showed deficits in the detection of social Faux Pas (0.80 ± 0.17 vs. controls: 0.94 ± 0.09, p = 0.025) and the correct identification of Theory of Mind stories (0.71 ± 0.13 vs. controls: 0.82 ± 0.12, p = 0.038). Relatives performed poorly in the Faces Test (0.83 ± 0.14 vs. controls: 0.9 ± 0.08, p = 0.048), the Reading the Mind in the Eyes Test (0.59 ± 0.17 vs. controls: 0.71 ± 0.14, p = 0.046) and the detection of social Faux Pas (0.8 ± 0.2 vs. controls: 0.93 ± 0.09, p = 0.024). Abnormalities were independent of age, years of education, and general cognitive performance in patients and their relatives. Performance in an Emotion Processing task (Faces Test) was correlated with performance in theory of mind tests in healthy individuals and relatives of patients with schizophrenia only. These results suggest that schizophrenia patients and their unaffected first-degree relatives display similar but nonidentical patterns of social cognition processing.
Fil: de Achaval, Delfina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Costanzo, Elsa Y.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Villarreal, Mirta Fabiana. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Jáuregui, Ignacio Oscar. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Chiodi, Araceli. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Castro, Mariana Nair. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Fahrer, Rodolfo D.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Leiguarda, Ramón C.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Chu, Elvina. University College London; Estados Unidos
Fil: Guinjoan, Salvador Martín. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Psicología; Argentina
Materia
Social Cognition
Endophenotype
Schizophrenia
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/16383
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/16383
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relativesde Achaval, DelfinaCostanzo, Elsa Y.Villarreal, Mirta FabianaJáuregui, Ignacio OscarChiodi, AraceliCastro, Mariana NairFahrer, Rodolfo D.Leiguarda, Ramón C.Chu, ElvinaGuinjoan, Salvador MartínSocial CognitionEndophenotypeSchizophreniahttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3https://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Previous studies have suggested that social cognition is affected in individuals with schizophrenia. The purpose of this study was to explore to what extent social cognition deficits are shared by unaffected first-degree relatives, and the nature of the relationship between performance in different paradigms of social cognition. 20 Schizophrenia patients (7 females, 31 ± 10 years), 20 healthy age- and gender-matched individuals, 20 unaffected first-degree relatives of the schizophrenia patients (11 females, 50 ± 20 years), and 20 healthy individuals matched for age and gender were recruited. Patients showed deficits in the detection of social Faux Pas (0.80 ± 0.17 vs. controls: 0.94 ± 0.09, p = 0.025) and the correct identification of Theory of Mind stories (0.71 ± 0.13 vs. controls: 0.82 ± 0.12, p = 0.038). Relatives performed poorly in the Faces Test (0.83 ± 0.14 vs. controls: 0.9 ± 0.08, p = 0.048), the Reading the Mind in the Eyes Test (0.59 ± 0.17 vs. controls: 0.71 ± 0.14, p = 0.046) and the detection of social Faux Pas (0.8 ± 0.2 vs. controls: 0.93 ± 0.09, p = 0.024). Abnormalities were independent of age, years of education, and general cognitive performance in patients and their relatives. Performance in an Emotion Processing task (Faces Test) was correlated with performance in theory of mind tests in healthy individuals and relatives of patients with schizophrenia only. These results suggest that schizophrenia patients and their unaffected first-degree relatives display similar but nonidentical patterns of social cognition processing.Fil: de Achaval, Delfina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Costanzo, Elsa Y.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Villarreal, Mirta Fabiana. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Jáuregui, Ignacio Oscar. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Chiodi, Araceli. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Castro, Mariana Nair. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Fahrer, Rodolfo D.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Leiguarda, Ramón C.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Chu, Elvina. University College London; Estados UnidosFil: Guinjoan, Salvador Martín. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Psicología; ArgentinaElsevier2010-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/16383de Achaval, Delfina; Costanzo, Elsa Y.; Villarreal, Mirta Fabiana; Jáuregui, Ignacio Oscar; Chiodi, Araceli; et al.; Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives; Elsevier; Neuropsychologia; 48; 5; 4-2010; 1209-12150028-3932enginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.neuropsychologia.2009.12.019info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0028393209004953info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:27:03Zoai:ri.conicet.gov.ar:11336/16383instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:27:03.341CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
title Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
spellingShingle Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
de Achaval, Delfina
Social Cognition
Endophenotype
Schizophrenia
title_short Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
title_full Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
title_fullStr Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
title_full_unstemmed Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
title_sort Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
dc.creator.none.fl_str_mv de Achaval, Delfina
Costanzo, Elsa Y.
Villarreal, Mirta Fabiana
Jáuregui, Ignacio Oscar
Chiodi, Araceli
Castro, Mariana Nair
Fahrer, Rodolfo D.
Leiguarda, Ramón C.
Chu, Elvina
Guinjoan, Salvador Martín
author de Achaval, Delfina
author_facet de Achaval, Delfina
Costanzo, Elsa Y.
Villarreal, Mirta Fabiana
Jáuregui, Ignacio Oscar
Chiodi, Araceli
Castro, Mariana Nair
Fahrer, Rodolfo D.
Leiguarda, Ramón C.
Chu, Elvina
Guinjoan, Salvador Martín
author_role author
author2 Costanzo, Elsa Y.
Villarreal, Mirta Fabiana
Jáuregui, Ignacio Oscar
Chiodi, Araceli
Castro, Mariana Nair
Fahrer, Rodolfo D.
Leiguarda, Ramón C.
Chu, Elvina
Guinjoan, Salvador Martín
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Social Cognition
Endophenotype
Schizophrenia
topic Social Cognition
Endophenotype
Schizophrenia
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Previous studies have suggested that social cognition is affected in individuals with schizophrenia. The purpose of this study was to explore to what extent social cognition deficits are shared by unaffected first-degree relatives, and the nature of the relationship between performance in different paradigms of social cognition. 20 Schizophrenia patients (7 females, 31 ± 10 years), 20 healthy age- and gender-matched individuals, 20 unaffected first-degree relatives of the schizophrenia patients (11 females, 50 ± 20 years), and 20 healthy individuals matched for age and gender were recruited. Patients showed deficits in the detection of social Faux Pas (0.80 ± 0.17 vs. controls: 0.94 ± 0.09, p = 0.025) and the correct identification of Theory of Mind stories (0.71 ± 0.13 vs. controls: 0.82 ± 0.12, p = 0.038). Relatives performed poorly in the Faces Test (0.83 ± 0.14 vs. controls: 0.9 ± 0.08, p = 0.048), the Reading the Mind in the Eyes Test (0.59 ± 0.17 vs. controls: 0.71 ± 0.14, p = 0.046) and the detection of social Faux Pas (0.8 ± 0.2 vs. controls: 0.93 ± 0.09, p = 0.024). Abnormalities were independent of age, years of education, and general cognitive performance in patients and their relatives. Performance in an Emotion Processing task (Faces Test) was correlated with performance in theory of mind tests in healthy individuals and relatives of patients with schizophrenia only. These results suggest that schizophrenia patients and their unaffected first-degree relatives display similar but nonidentical patterns of social cognition processing.
Fil: de Achaval, Delfina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Costanzo, Elsa Y.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Villarreal, Mirta Fabiana. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Jáuregui, Ignacio Oscar. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Chiodi, Araceli. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Castro, Mariana Nair. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Fahrer, Rodolfo D.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Leiguarda, Ramón C.. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina
Fil: Chu, Elvina. University College London; Estados Unidos
Fil: Guinjoan, Salvador Martín. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Psicología; Argentina
description Previous studies have suggested that social cognition is affected in individuals with schizophrenia. The purpose of this study was to explore to what extent social cognition deficits are shared by unaffected first-degree relatives, and the nature of the relationship between performance in different paradigms of social cognition. 20 Schizophrenia patients (7 females, 31 ± 10 years), 20 healthy age- and gender-matched individuals, 20 unaffected first-degree relatives of the schizophrenia patients (11 females, 50 ± 20 years), and 20 healthy individuals matched for age and gender were recruited. Patients showed deficits in the detection of social Faux Pas (0.80 ± 0.17 vs. controls: 0.94 ± 0.09, p = 0.025) and the correct identification of Theory of Mind stories (0.71 ± 0.13 vs. controls: 0.82 ± 0.12, p = 0.038). Relatives performed poorly in the Faces Test (0.83 ± 0.14 vs. controls: 0.9 ± 0.08, p = 0.048), the Reading the Mind in the Eyes Test (0.59 ± 0.17 vs. controls: 0.71 ± 0.14, p = 0.046) and the detection of social Faux Pas (0.8 ± 0.2 vs. controls: 0.93 ± 0.09, p = 0.024). Abnormalities were independent of age, years of education, and general cognitive performance in patients and their relatives. Performance in an Emotion Processing task (Faces Test) was correlated with performance in theory of mind tests in healthy individuals and relatives of patients with schizophrenia only. These results suggest that schizophrenia patients and their unaffected first-degree relatives display similar but nonidentical patterns of social cognition processing.
publishDate 2010
dc.date.none.fl_str_mv 2010-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/16383
de Achaval, Delfina; Costanzo, Elsa Y.; Villarreal, Mirta Fabiana; Jáuregui, Ignacio Oscar; Chiodi, Araceli; et al.; Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives; Elsevier; Neuropsychologia; 48; 5; 4-2010; 1209-1215
0028-3932
url http://hdl.handle.net/11336/16383
identifier_str_mv de Achaval, Delfina; Costanzo, Elsa Y.; Villarreal, Mirta Fabiana; Jáuregui, Ignacio Oscar; Chiodi, Araceli; et al.; Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives; Elsevier; Neuropsychologia; 48; 5; 4-2010; 1209-1215
0028-3932
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.neuropsychologia.2009.12.019
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0028393209004953
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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