The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes
- Autores
- Gutiérrez, Antonio M.; Echevarría, Miriam; Whittembury, Guillermo
- Año de publicación
- 2006
- Idioma
- inglés
- Tipo de recurso
- reseña artículo
- Estado
- versión publicada
- Descripción
- We overview the critical steps leading to the demonstration that each ~28 kD protein monomer of the water channel (or pore)¹ pierce the lipid bilayer part of the cell membrane allowing the passage of ~ 10¹³ water molecules per second. The biophysical approach gives a functional and physical image of the water pore close to what has recently been obtained from the amino acid sequence, crystallography and other advances from the cloning era of trans-membrane water transport. Paracellular “wide” water channels of some leaky epithelia are not covered here [cf. Whittembury and Reuss, 1992; Whittembury and Hill, 2000].
Sociedad Argentina de Fisiología - Materia
-
Ciencias Médicas
Fisiología
Aquaporin
Water channels
Cell membrane - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by/4.0/
- Repositorio
.jpg)
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/146979
Ver los metadatos del registro completo
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The old water channels are aquaporin proteins through which single files of water molecules cross cell membranesGutiérrez, Antonio M.Echevarría, MiriamWhittembury, GuillermoCiencias MédicasFisiologíaAquaporinWater channelsCell membraneWe overview the critical steps leading to the demonstration that each ~28 kD protein monomer of the water channel (or pore)¹ pierce the lipid bilayer part of the cell membrane allowing the passage of ~ 10¹³ water molecules per second. The biophysical approach gives a functional and physical image of the water pore close to what has recently been obtained from the amino acid sequence, crystallography and other advances from the cloning era of trans-membrane water transport. Paracellular “wide” water channels of some leaky epithelia are not covered here [cf. Whittembury and Reuss, 1992; Whittembury and Hill, 2000].Sociedad Argentina de Fisiología2006-05info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionRevisionhttp://purl.org/coar/resource_type/c_dcae04bcinfo:ar-repo/semantics/resenaArticuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/146979enginfo:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/wp-content/uploads/2022/09/vol1_n10_may.pdfinfo:eu-repo/semantics/altIdentifier/issn/1669-5410info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-10-22T17:18:26Zoai:sedici.unlp.edu.ar:10915/146979Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-10-22 17:18:26.922SEDICI (UNLP) - Universidad Nacional de La Platafalse |
| dc.title.none.fl_str_mv |
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes |
| title |
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes |
| spellingShingle |
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes Gutiérrez, Antonio M. Ciencias Médicas Fisiología Aquaporin Water channels Cell membrane |
| title_short |
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes |
| title_full |
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes |
| title_fullStr |
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes |
| title_full_unstemmed |
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes |
| title_sort |
The old water channels are aquaporin proteins through which single files of water molecules cross cell membranes |
| dc.creator.none.fl_str_mv |
Gutiérrez, Antonio M. Echevarría, Miriam Whittembury, Guillermo |
| author |
Gutiérrez, Antonio M. |
| author_facet |
Gutiérrez, Antonio M. Echevarría, Miriam Whittembury, Guillermo |
| author_role |
author |
| author2 |
Echevarría, Miriam Whittembury, Guillermo |
| author2_role |
author author |
| dc.subject.none.fl_str_mv |
Ciencias Médicas Fisiología Aquaporin Water channels Cell membrane |
| topic |
Ciencias Médicas Fisiología Aquaporin Water channels Cell membrane |
| dc.description.none.fl_txt_mv |
We overview the critical steps leading to the demonstration that each ~28 kD protein monomer of the water channel (or pore)¹ pierce the lipid bilayer part of the cell membrane allowing the passage of ~ 10¹³ water molecules per second. The biophysical approach gives a functional and physical image of the water pore close to what has recently been obtained from the amino acid sequence, crystallography and other advances from the cloning era of trans-membrane water transport. Paracellular “wide” water channels of some leaky epithelia are not covered here [cf. Whittembury and Reuss, 1992; Whittembury and Hill, 2000]. Sociedad Argentina de Fisiología |
| description |
We overview the critical steps leading to the demonstration that each ~28 kD protein monomer of the water channel (or pore)¹ pierce the lipid bilayer part of the cell membrane allowing the passage of ~ 10¹³ water molecules per second. The biophysical approach gives a functional and physical image of the water pore close to what has recently been obtained from the amino acid sequence, crystallography and other advances from the cloning era of trans-membrane water transport. Paracellular “wide” water channels of some leaky epithelia are not covered here [cf. Whittembury and Reuss, 1992; Whittembury and Hill, 2000]. |
| publishDate |
2006 |
| dc.date.none.fl_str_mv |
2006-05 |
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info:eu-repo/semantics/review info:eu-repo/semantics/publishedVersion Revision http://purl.org/coar/resource_type/c_dcae04bc info:ar-repo/semantics/resenaArticulo |
| format |
review |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://sedici.unlp.edu.ar/handle/10915/146979 |
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http://sedici.unlp.edu.ar/handle/10915/146979 |
| dc.language.none.fl_str_mv |
eng |
| language |
eng |
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info:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/wp-content/uploads/2022/09/vol1_n10_may.pdf info:eu-repo/semantics/altIdentifier/issn/1669-5410 |
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info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) |
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openAccess |
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http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) |
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