Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node

Autores
Tasé, David Alejandro Jorge; Garavaglia, Leopoldo; Defeo, Magdalena María; Irurzun, Isabel María
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This study focused on the complex structure of heart rate variability (HRV) in the healthy heart. We studied the behavior of the heart rate variability (HRV) in healthy humans as a function of age from conception, including fetal data. We calculated statistical quantities such as the mean value of RR intervals (<RR>), the standard deviation of these intervals (SD), the power of the very low frequency (VLF), low frequency (LF) and high frequency (HF) bands, and the large-scale properties of HRV. We rationalized our findings discussing previous results that identify the signatures of the sinoatrial node (SAN) and the autonomic nervous system (ANS) in the HRV. This work provides further insights into the contribution of the SAN and the ANS to the cardiac rhythm in humans.
Centro de Investigaciones Ópticas
Materia
Ciencias Médicas
heart rate variability
sinoatrial node
autonomic nervous system
fibrosis
scaling
white noise
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/193513
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/193513
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial nodeTasé, David Alejandro JorgeGaravaglia, LeopoldoDefeo, Magdalena MaríaIrurzun, Isabel MaríaCiencias Médicasheart rate variabilitysinoatrial nodeautonomic nervous systemfibrosisscalingwhite noiseThis study focused on the complex structure of heart rate variability (HRV) in the healthy heart. We studied the behavior of the heart rate variability (HRV) in healthy humans as a function of age from conception, including fetal data. We calculated statistical quantities such as the mean value of RR intervals (&lt;RR&gt;), the standard deviation of these intervals (SD), the power of the very low frequency (VLF), low frequency (LF) and high frequency (HF) bands, and the large-scale properties of HRV. We rationalized our findings discussing previous results that identify the signatures of the sinoatrial node (SAN) and the autonomic nervous system (ANS) in the HRV. This work provides further insights into the contribution of the SAN and the ANS to the cardiac rhythm in humans.Centro de Investigaciones Ópticas2025-08-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://doi.org/10.3389/fmed.2025.1597299http://sedici.unlp.edu.ar/handle/10915/193513enginfo:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1597299/pdfinfo:eu-repo/semantics/altIdentifier/issn/2296-858Xinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2026-05-06T13:00:49Zoai:sedici.unlp.edu.ar:10915/193513Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292026-05-06 13:00:49.942SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node
title Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node
spellingShingle Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node
Tasé, David Alejandro Jorge
Ciencias Médicas
heart rate variability
sinoatrial node
autonomic nervous system
fibrosis
scaling
white noise
title_short Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node
title_full Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node
title_fullStr Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node
title_full_unstemmed Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node
title_sort Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node
dc.creator.none.fl_str_mv Tasé, David Alejandro Jorge
Garavaglia, Leopoldo
Defeo, Magdalena María
Irurzun, Isabel María
author Tasé, David Alejandro Jorge
author_facet Tasé, David Alejandro Jorge
Garavaglia, Leopoldo
Defeo, Magdalena María
Irurzun, Isabel María
author_role author
author2 Garavaglia, Leopoldo
Defeo, Magdalena María
Irurzun, Isabel María
author2_role author
author
author
dc.subject.none.fl_str_mv Ciencias Médicas
heart rate variability
sinoatrial node
autonomic nervous system
fibrosis
scaling
white noise
topic Ciencias Médicas
heart rate variability
sinoatrial node
autonomic nervous system
fibrosis
scaling
white noise
dc.description.none.fl_txt_mv This study focused on the complex structure of heart rate variability (HRV) in the healthy heart. We studied the behavior of the heart rate variability (HRV) in healthy humans as a function of age from conception, including fetal data. We calculated statistical quantities such as the mean value of RR intervals (&lt;RR&gt;), the standard deviation of these intervals (SD), the power of the very low frequency (VLF), low frequency (LF) and high frequency (HF) bands, and the large-scale properties of HRV. We rationalized our findings discussing previous results that identify the signatures of the sinoatrial node (SAN) and the autonomic nervous system (ANS) in the HRV. This work provides further insights into the contribution of the SAN and the ANS to the cardiac rhythm in humans.
Centro de Investigaciones Ópticas
description This study focused on the complex structure of heart rate variability (HRV) in the healthy heart. We studied the behavior of the heart rate variability (HRV) in healthy humans as a function of age from conception, including fetal data. We calculated statistical quantities such as the mean value of RR intervals (&lt;RR&gt;), the standard deviation of these intervals (SD), the power of the very low frequency (VLF), low frequency (LF) and high frequency (HF) bands, and the large-scale properties of HRV. We rationalized our findings discussing previous results that identify the signatures of the sinoatrial node (SAN) and the autonomic nervous system (ANS) in the HRV. This work provides further insights into the contribution of the SAN and the ANS to the cardiac rhythm in humans.
publishDate 2025
dc.date.none.fl_str_mv 2025-08-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3389/fmed.2025.1597299
http://sedici.unlp.edu.ar/handle/10915/193513
url https://doi.org/10.3389/fmed.2025.1597299
http://sedici.unlp.edu.ar/handle/10915/193513
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1597299/pdf
info:eu-repo/semantics/altIdentifier/issn/2296-858X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.1485815

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