HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams

Autores
Da Silva, R. Celerino; Bedin, E.; Mangano, Andrea María Mercedes; Aulicino, Paula; Pontillo, A.; Brandão, L.; Guimarães, R.; Arraes, L. C.; Sen, Luisa; Crovella, Sergio
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Human immunodeficiency virus (HIV) mother-to-child transmission is a complex event, depending upon environmental factors and is affected by host genetic factors from mother and child, as well as viral genetic elements. The integration of multiple parameters (CD4 cell count, virus load, HIV subtype, and host genetic markers) could account for the susceptibility to HIV infection, a multifactorial trait. The goal of this manuscript is to analyze the immunogenetic factors associated to HIV mother-to-child transmission, trying to unravel the genetic puzzle of HIV mother-to-child transmission and considering the experience in this topic of two research groups from Brazil and Argentina.
Fil: Da Silva, R. Celerino. Universidade Federal de Pernambuco; Brasil
Fil: Bedin, E.. Institute for Maternal and Child Health; Italia
Fil: Mangano, Andrea María Mercedes. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aulicino, Paula. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pontillo, A.. Universidade de Sao Paulo; Brasil
Fil: Brandão, L.. Universidade Federal de Pernambuco; Brasil
Fil: Guimarães, R.. Universidade Federal de Pernambuco; Brasil
Fil: Arraes, L. C.. Institute of Integral Medicine Professor Fernando Figueira; Brasil
Fil: Sen, Luisa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Crovella, Sergio. Università degli Studi di Trieste; Italia
Materia
Mother-To-Child Transmission
Hiv
Host Genome
Immunogenetics Markers
Susceptibility
Protection
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/23960
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teamsDa Silva, R. CelerinoBedin, E.Mangano, Andrea María MercedesAulicino, PaulaPontillo, A.Brandão, L.Guimarães, R.Arraes, L. C.Sen, LuisaCrovella, SergioMother-To-Child TransmissionHivHost GenomeImmunogenetics MarkersSusceptibilityProtectionhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Human immunodeficiency virus (HIV) mother-to-child transmission is a complex event, depending upon environmental factors and is affected by host genetic factors from mother and child, as well as viral genetic elements. The integration of multiple parameters (CD4 cell count, virus load, HIV subtype, and host genetic markers) could account for the susceptibility to HIV infection, a multifactorial trait. The goal of this manuscript is to analyze the immunogenetic factors associated to HIV mother-to-child transmission, trying to unravel the genetic puzzle of HIV mother-to-child transmission and considering the experience in this topic of two research groups from Brazil and Argentina.Fil: Da Silva, R. Celerino. Universidade Federal de Pernambuco; BrasilFil: Bedin, E.. Institute for Maternal and Child Health; ItaliaFil: Mangano, Andrea María Mercedes. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Aulicino, Paula. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pontillo, A.. Universidade de Sao Paulo; BrasilFil: Brandão, L.. Universidade Federal de Pernambuco; BrasilFil: Guimarães, R.. Universidade Federal de Pernambuco; BrasilFil: Arraes, L. C.. Institute of Integral Medicine Professor Fernando Figueira; BrasilFil: Sen, Luisa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Crovella, Sergio. Università degli Studi di Trieste; ItaliaElsevier2013-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/23960Da Silva, R. Celerino; Bedin, E.; Mangano, Andrea María Mercedes; Aulicino, Paula; Pontillo, A.; et al.; HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams; Elsevier; Infection, Genetics and Evolution; 19; 3-2013; 1-121567-1348CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1567134813000762info:eu-repo/semantics/altIdentifier/doi/10.1016/j.meegid.2013.03.005info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:11:16Zoai:ri.conicet.gov.ar:11336/23960instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:11:16.544CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams
title HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams
spellingShingle HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams
Da Silva, R. Celerino
Mother-To-Child Transmission
Hiv
Host Genome
Immunogenetics Markers
Susceptibility
Protection
title_short HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams
title_full HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams
title_fullStr HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams
title_full_unstemmed HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams
title_sort HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams
dc.creator.none.fl_str_mv Da Silva, R. Celerino
Bedin, E.
Mangano, Andrea María Mercedes
Aulicino, Paula
Pontillo, A.
Brandão, L.
Guimarães, R.
Arraes, L. C.
Sen, Luisa
Crovella, Sergio
author Da Silva, R. Celerino
author_facet Da Silva, R. Celerino
Bedin, E.
Mangano, Andrea María Mercedes
Aulicino, Paula
Pontillo, A.
Brandão, L.
Guimarães, R.
Arraes, L. C.
Sen, Luisa
Crovella, Sergio
author_role author
author2 Bedin, E.
Mangano, Andrea María Mercedes
Aulicino, Paula
Pontillo, A.
Brandão, L.
Guimarães, R.
Arraes, L. C.
Sen, Luisa
Crovella, Sergio
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Mother-To-Child Transmission
Hiv
Host Genome
Immunogenetics Markers
Susceptibility
Protection
topic Mother-To-Child Transmission
Hiv
Host Genome
Immunogenetics Markers
Susceptibility
Protection
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Human immunodeficiency virus (HIV) mother-to-child transmission is a complex event, depending upon environmental factors and is affected by host genetic factors from mother and child, as well as viral genetic elements. The integration of multiple parameters (CD4 cell count, virus load, HIV subtype, and host genetic markers) could account for the susceptibility to HIV infection, a multifactorial trait. The goal of this manuscript is to analyze the immunogenetic factors associated to HIV mother-to-child transmission, trying to unravel the genetic puzzle of HIV mother-to-child transmission and considering the experience in this topic of two research groups from Brazil and Argentina.
Fil: Da Silva, R. Celerino. Universidade Federal de Pernambuco; Brasil
Fil: Bedin, E.. Institute for Maternal and Child Health; Italia
Fil: Mangano, Andrea María Mercedes. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aulicino, Paula. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pontillo, A.. Universidade de Sao Paulo; Brasil
Fil: Brandão, L.. Universidade Federal de Pernambuco; Brasil
Fil: Guimarães, R.. Universidade Federal de Pernambuco; Brasil
Fil: Arraes, L. C.. Institute of Integral Medicine Professor Fernando Figueira; Brasil
Fil: Sen, Luisa. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan". Laboratorio de Biología Celular y Retrovirus; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Crovella, Sergio. Università degli Studi di Trieste; Italia
description Human immunodeficiency virus (HIV) mother-to-child transmission is a complex event, depending upon environmental factors and is affected by host genetic factors from mother and child, as well as viral genetic elements. The integration of multiple parameters (CD4 cell count, virus load, HIV subtype, and host genetic markers) could account for the susceptibility to HIV infection, a multifactorial trait. The goal of this manuscript is to analyze the immunogenetic factors associated to HIV mother-to-child transmission, trying to unravel the genetic puzzle of HIV mother-to-child transmission and considering the experience in this topic of two research groups from Brazil and Argentina.
publishDate 2013
dc.date.none.fl_str_mv 2013-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/23960
Da Silva, R. Celerino; Bedin, E.; Mangano, Andrea María Mercedes; Aulicino, Paula; Pontillo, A.; et al.; HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams; Elsevier; Infection, Genetics and Evolution; 19; 3-2013; 1-12
1567-1348
CONICET Digital
CONICET
url http://hdl.handle.net/11336/23960
identifier_str_mv Da Silva, R. Celerino; Bedin, E.; Mangano, Andrea María Mercedes; Aulicino, Paula; Pontillo, A.; et al.; HIV mother-to-child transmission: A complex genetic puzzle tacked by Brazil and Argentina research teams; Elsevier; Infection, Genetics and Evolution; 19; 3-2013; 1-12
1567-1348
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1567134813000762
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.meegid.2013.03.005
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842980575849218048
score 12.993085

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