Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated f...

Autores
Takahashi, Yoshiko; Avila, Susana; Correa, Silvia; Cardone, Karina; Fernández, Mariana; Crudo, Favio; Sato, Miho; Aiga, Hirotsugu; Hirayama, Kenji; Perez, Freddy; Periago, Maria Victoria
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T. cruzi and hepatitis B. The study further attempted to identify the barriers to and facilitators for preventing MTCT of T. cruzi and HBV in the Gran Chaco region of Argentina and Paraguay. Methods Data on T. cruzi and HBV screening and treatment among pregnant women and infants were collected from antenatal care (ANC) registries between June 2018 and December 2022. A cascade-of-care analysis was applied to assess the intervention’s effectiveness and identify bottlenecks. Additionally, key informant interviews were conducted for both implementors and service recipients to identify barriers to and facilitators for accessing screening and treatment using the Consolidated Framework for Implementation Research. Results A total of 1,658 pregnant women were recruited, achieving 100% antenatal care coverage and screening for T. cruzi and HBV. The prevalence of T. cruzi among pregnant women was 3.3% (95%CI: 2.4-4.1%), while in newborns it was 14.0% (95% CI: 6.0–25.0). Treatment coverage for newborns infected with T. cruzi was 100%, whereas postdelivery treatment coverage among mothers was 67.3%. This achievement was likely attributed to strong community engagement, contributing to 100% ANC coverage. However, barriers such as a fragile local health system, long-term follow-up requirements, high mobile populations, cultural beliefs, and social trauma were identified in target areas.
Fil: Takahashi, Yoshiko. Nagasaki University; Japón. Niigata University of Health and Welfare; Japón
Fil: Avila, Susana. Fundación Mundo Sano; Argentina
Fil: Correa, Silvia. Universidad Nacional de Salta; Argentina
Fil: Cardone, Karina. Fundación Mundo Sano; Argentina
Fil: Fernández, Mariana. Fundación Mundo Sano; Argentina
Fil: Crudo, Favio. Fundación Mundo Sano; Argentina
Fil: Sato, Miho. Nagasaki University; Japón
Fil: Aiga, Hirotsugu. Nagasaki University; Japón
Fil: Hirayama, Kenji. Nagasaki University; Japón
Fil: Perez, Freddy. Organizacion Mundial de la Salud; Argentina. Universidade Federal de Ciências da Saúde de Porto Alegre; Brasil
Fil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; Argentina
Materia
TRYPANOSOMA CRUZI
CHAGAS DISEASE
HEPATITIS B
MOTHER-TO-CHILD TRANSMISSION
GRAN CHACO
PREGNANT WOMEN
EMTCT PLUS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/251716
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/251716
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)Takahashi, YoshikoAvila, SusanaCorrea, SilviaCardone, KarinaFernández, MarianaCrudo, FavioSato, MihoAiga, HirotsuguHirayama, KenjiPerez, FreddyPeriago, Maria VictoriaTRYPANOSOMA CRUZICHAGAS DISEASEHEPATITIS BMOTHER-TO-CHILD TRANSMISSIONGRAN CHACOPREGNANT WOMENEMTCT PLUShttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T. cruzi and hepatitis B. The study further attempted to identify the barriers to and facilitators for preventing MTCT of T. cruzi and HBV in the Gran Chaco region of Argentina and Paraguay. Methods Data on T. cruzi and HBV screening and treatment among pregnant women and infants were collected from antenatal care (ANC) registries between June 2018 and December 2022. A cascade-of-care analysis was applied to assess the intervention’s effectiveness and identify bottlenecks. Additionally, key informant interviews were conducted for both implementors and service recipients to identify barriers to and facilitators for accessing screening and treatment using the Consolidated Framework for Implementation Research. Results A total of 1,658 pregnant women were recruited, achieving 100% antenatal care coverage and screening for T. cruzi and HBV. The prevalence of T. cruzi among pregnant women was 3.3% (95%CI: 2.4-4.1%), while in newborns it was 14.0% (95% CI: 6.0–25.0). Treatment coverage for newborns infected with T. cruzi was 100%, whereas postdelivery treatment coverage among mothers was 67.3%. This achievement was likely attributed to strong community engagement, contributing to 100% ANC coverage. However, barriers such as a fragile local health system, long-term follow-up requirements, high mobile populations, cultural beliefs, and social trauma were identified in target areas.Fil: Takahashi, Yoshiko. Nagasaki University; Japón. Niigata University of Health and Welfare; JapónFil: Avila, Susana. Fundación Mundo Sano; ArgentinaFil: Correa, Silvia. Universidad Nacional de Salta; ArgentinaFil: Cardone, Karina. Fundación Mundo Sano; ArgentinaFil: Fernández, Mariana. Fundación Mundo Sano; ArgentinaFil: Crudo, Favio. Fundación Mundo Sano; ArgentinaFil: Sato, Miho. Nagasaki University; JapónFil: Aiga, Hirotsugu. Nagasaki University; JapónFil: Hirayama, Kenji. Nagasaki University; JapónFil: Perez, Freddy. Organizacion Mundial de la Salud; Argentina. Universidade Federal de Ciências da Saúde de Porto Alegre; BrasilFil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; ArgentinaBioMed Central2024-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/251716Takahashi, Yoshiko; Avila, Susana; Correa, Silvia; Cardone, Karina; Fernández, Mariana; et al.; Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR); BioMed Central; BMC Primary Care; 25; 1; 12-2024; 1-102731-4553CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://bmcprimcare.biomedcentral.com/articles/10.1186/s12875-024-02683-zinfo:eu-repo/semantics/altIdentifier/doi/10.1186/s12875-024-02683-zinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:03:08Zoai:ri.conicet.gov.ar:11336/251716instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:03:08.34CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)
title Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)
spellingShingle Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)
Takahashi, Yoshiko
TRYPANOSOMA CRUZI
CHAGAS DISEASE
HEPATITIS B
MOTHER-TO-CHILD TRANSMISSION
GRAN CHACO
PREGNANT WOMEN
EMTCT PLUS
title_short Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)
title_full Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)
title_fullStr Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)
title_full_unstemmed Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)
title_sort Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)
dc.creator.none.fl_str_mv Takahashi, Yoshiko
Avila, Susana
Correa, Silvia
Cardone, Karina
Fernández, Mariana
Crudo, Favio
Sato, Miho
Aiga, Hirotsugu
Hirayama, Kenji
Perez, Freddy
Periago, Maria Victoria
author Takahashi, Yoshiko
author_facet Takahashi, Yoshiko
Avila, Susana
Correa, Silvia
Cardone, Karina
Fernández, Mariana
Crudo, Favio
Sato, Miho
Aiga, Hirotsugu
Hirayama, Kenji
Perez, Freddy
Periago, Maria Victoria
author_role author
author2 Avila, Susana
Correa, Silvia
Cardone, Karina
Fernández, Mariana
Crudo, Favio
Sato, Miho
Aiga, Hirotsugu
Hirayama, Kenji
Perez, Freddy
Periago, Maria Victoria
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv TRYPANOSOMA CRUZI
CHAGAS DISEASE
HEPATITIS B
MOTHER-TO-CHILD TRANSMISSION
GRAN CHACO
PREGNANT WOMEN
EMTCT PLUS
topic TRYPANOSOMA CRUZI
CHAGAS DISEASE
HEPATITIS B
MOTHER-TO-CHILD TRANSMISSION
GRAN CHACO
PREGNANT WOMEN
EMTCT PLUS
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T. cruzi and hepatitis B. The study further attempted to identify the barriers to and facilitators for preventing MTCT of T. cruzi and HBV in the Gran Chaco region of Argentina and Paraguay. Methods Data on T. cruzi and HBV screening and treatment among pregnant women and infants were collected from antenatal care (ANC) registries between June 2018 and December 2022. A cascade-of-care analysis was applied to assess the intervention’s effectiveness and identify bottlenecks. Additionally, key informant interviews were conducted for both implementors and service recipients to identify barriers to and facilitators for accessing screening and treatment using the Consolidated Framework for Implementation Research. Results A total of 1,658 pregnant women were recruited, achieving 100% antenatal care coverage and screening for T. cruzi and HBV. The prevalence of T. cruzi among pregnant women was 3.3% (95%CI: 2.4-4.1%), while in newborns it was 14.0% (95% CI: 6.0–25.0). Treatment coverage for newborns infected with T. cruzi was 100%, whereas postdelivery treatment coverage among mothers was 67.3%. This achievement was likely attributed to strong community engagement, contributing to 100% ANC coverage. However, barriers such as a fragile local health system, long-term follow-up requirements, high mobile populations, cultural beliefs, and social trauma were identified in target areas.
Fil: Takahashi, Yoshiko. Nagasaki University; Japón. Niigata University of Health and Welfare; Japón
Fil: Avila, Susana. Fundación Mundo Sano; Argentina
Fil: Correa, Silvia. Universidad Nacional de Salta; Argentina
Fil: Cardone, Karina. Fundación Mundo Sano; Argentina
Fil: Fernández, Mariana. Fundación Mundo Sano; Argentina
Fil: Crudo, Favio. Fundación Mundo Sano; Argentina
Fil: Sato, Miho. Nagasaki University; Japón
Fil: Aiga, Hirotsugu. Nagasaki University; Japón
Fil: Hirayama, Kenji. Nagasaki University; Japón
Fil: Perez, Freddy. Organizacion Mundial de la Salud; Argentina. Universidade Federal de Ciências da Saúde de Porto Alegre; Brasil
Fil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; Argentina
description Background Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T. cruzi and hepatitis B. The study further attempted to identify the barriers to and facilitators for preventing MTCT of T. cruzi and HBV in the Gran Chaco region of Argentina and Paraguay. Methods Data on T. cruzi and HBV screening and treatment among pregnant women and infants were collected from antenatal care (ANC) registries between June 2018 and December 2022. A cascade-of-care analysis was applied to assess the intervention’s effectiveness and identify bottlenecks. Additionally, key informant interviews were conducted for both implementors and service recipients to identify barriers to and facilitators for accessing screening and treatment using the Consolidated Framework for Implementation Research. Results A total of 1,658 pregnant women were recruited, achieving 100% antenatal care coverage and screening for T. cruzi and HBV. The prevalence of T. cruzi among pregnant women was 3.3% (95%CI: 2.4-4.1%), while in newborns it was 14.0% (95% CI: 6.0–25.0). Treatment coverage for newborns infected with T. cruzi was 100%, whereas postdelivery treatment coverage among mothers was 67.3%. This achievement was likely attributed to strong community engagement, contributing to 100% ANC coverage. However, barriers such as a fragile local health system, long-term follow-up requirements, high mobile populations, cultural beliefs, and social trauma were identified in target areas.
publishDate 2024
dc.date.none.fl_str_mv 2024-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/251716
Takahashi, Yoshiko; Avila, Susana; Correa, Silvia; Cardone, Karina; Fernández, Mariana; et al.; Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR); BioMed Central; BMC Primary Care; 25; 1; 12-2024; 1-10
2731-4553
CONICET Digital
CONICET
url http://hdl.handle.net/11336/251716
identifier_str_mv Takahashi, Yoshiko; Avila, Susana; Correa, Silvia; Cardone, Karina; Fernández, Mariana; et al.; Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR); BioMed Central; BMC Primary Care; 25; 1; 12-2024; 1-10
2731-4553
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://bmcprimcare.biomedcentral.com/articles/10.1186/s12875-024-02683-z
info:eu-repo/semantics/altIdentifier/doi/10.1186/s12875-024-02683-z
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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