Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated f...
- Autores
- Takahashi, Yoshiko; Avila, Susana; Correa, Silvia; Cardone, Karina; Fernández, Mariana; Crudo, Favio; Sato, Miho; Aiga, Hirotsugu; Hirayama, Kenji; Perez, Freddy; Periago, Maria Victoria
- Año de publicación
- 2024
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Background Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T. cruzi and hepatitis B. The study further attempted to identify the barriers to and facilitators for preventing MTCT of T. cruzi and HBV in the Gran Chaco region of Argentina and Paraguay. Methods Data on T. cruzi and HBV screening and treatment among pregnant women and infants were collected from antenatal care (ANC) registries between June 2018 and December 2022. A cascade-of-care analysis was applied to assess the intervention’s effectiveness and identify bottlenecks. Additionally, key informant interviews were conducted for both implementors and service recipients to identify barriers to and facilitators for accessing screening and treatment using the Consolidated Framework for Implementation Research. Results A total of 1,658 pregnant women were recruited, achieving 100% antenatal care coverage and screening for T. cruzi and HBV. The prevalence of T. cruzi among pregnant women was 3.3% (95%CI: 2.4-4.1%), while in newborns it was 14.0% (95% CI: 6.0–25.0). Treatment coverage for newborns infected with T. cruzi was 100%, whereas postdelivery treatment coverage among mothers was 67.3%. This achievement was likely attributed to strong community engagement, contributing to 100% ANC coverage. However, barriers such as a fragile local health system, long-term follow-up requirements, high mobile populations, cultural beliefs, and social trauma were identified in target areas.
Fil: Takahashi, Yoshiko. Nagasaki University; Japón. Niigata University of Health and Welfare; Japón
Fil: Avila, Susana. Fundación Mundo Sano; Argentina
Fil: Correa, Silvia. Universidad Nacional de Salta; Argentina
Fil: Cardone, Karina. Fundación Mundo Sano; Argentina
Fil: Fernández, Mariana. Fundación Mundo Sano; Argentina
Fil: Crudo, Favio. Fundación Mundo Sano; Argentina
Fil: Sato, Miho. Nagasaki University; Japón
Fil: Aiga, Hirotsugu. Nagasaki University; Japón
Fil: Hirayama, Kenji. Nagasaki University; Japón
Fil: Perez, Freddy. Organizacion Mundial de la Salud; Argentina. Universidade Federal de Ciências da Saúde de Porto Alegre; Brasil
Fil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; Argentina - Materia
-
TRYPANOSOMA CRUZI
CHAGAS DISEASE
HEPATITIS B
MOTHER-TO-CHILD TRANSMISSION
GRAN CHACO
PREGNANT WOMEN
EMTCT PLUS - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/251716
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3498 |
network_name_str |
CONICET Digital (CONICET) |
spelling |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR)Takahashi, YoshikoAvila, SusanaCorrea, SilviaCardone, KarinaFernández, MarianaCrudo, FavioSato, MihoAiga, HirotsuguHirayama, KenjiPerez, FreddyPeriago, Maria VictoriaTRYPANOSOMA CRUZICHAGAS DISEASEHEPATITIS BMOTHER-TO-CHILD TRANSMISSIONGRAN CHACOPREGNANT WOMENEMTCT PLUShttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T. cruzi and hepatitis B. The study further attempted to identify the barriers to and facilitators for preventing MTCT of T. cruzi and HBV in the Gran Chaco region of Argentina and Paraguay. Methods Data on T. cruzi and HBV screening and treatment among pregnant women and infants were collected from antenatal care (ANC) registries between June 2018 and December 2022. A cascade-of-care analysis was applied to assess the intervention’s effectiveness and identify bottlenecks. Additionally, key informant interviews were conducted for both implementors and service recipients to identify barriers to and facilitators for accessing screening and treatment using the Consolidated Framework for Implementation Research. Results A total of 1,658 pregnant women were recruited, achieving 100% antenatal care coverage and screening for T. cruzi and HBV. The prevalence of T. cruzi among pregnant women was 3.3% (95%CI: 2.4-4.1%), while in newborns it was 14.0% (95% CI: 6.0–25.0). Treatment coverage for newborns infected with T. cruzi was 100%, whereas postdelivery treatment coverage among mothers was 67.3%. This achievement was likely attributed to strong community engagement, contributing to 100% ANC coverage. However, barriers such as a fragile local health system, long-term follow-up requirements, high mobile populations, cultural beliefs, and social trauma were identified in target areas.Fil: Takahashi, Yoshiko. Nagasaki University; Japón. Niigata University of Health and Welfare; JapónFil: Avila, Susana. Fundación Mundo Sano; ArgentinaFil: Correa, Silvia. Universidad Nacional de Salta; ArgentinaFil: Cardone, Karina. Fundación Mundo Sano; ArgentinaFil: Fernández, Mariana. Fundación Mundo Sano; ArgentinaFil: Crudo, Favio. Fundación Mundo Sano; ArgentinaFil: Sato, Miho. Nagasaki University; JapónFil: Aiga, Hirotsugu. Nagasaki University; JapónFil: Hirayama, Kenji. Nagasaki University; JapónFil: Perez, Freddy. Organizacion Mundial de la Salud; Argentina. Universidade Federal de Ciências da Saúde de Porto Alegre; BrasilFil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; ArgentinaBioMed Central2024-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/251716Takahashi, Yoshiko; Avila, Susana; Correa, Silvia; Cardone, Karina; Fernández, Mariana; et al.; Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR); BioMed Central; BMC Primary Care; 25; 1; 12-2024; 1-102731-4553CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://bmcprimcare.biomedcentral.com/articles/10.1186/s12875-024-02683-zinfo:eu-repo/semantics/altIdentifier/doi/10.1186/s12875-024-02683-zinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:35:06Zoai:ri.conicet.gov.ar:11336/251716instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:35:07.152CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR) |
title |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR) |
spellingShingle |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR) Takahashi, Yoshiko TRYPANOSOMA CRUZI CHAGAS DISEASE HEPATITIS B MOTHER-TO-CHILD TRANSMISSION GRAN CHACO PREGNANT WOMEN EMTCT PLUS |
title_short |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR) |
title_full |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR) |
title_fullStr |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR) |
title_full_unstemmed |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR) |
title_sort |
Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR) |
dc.creator.none.fl_str_mv |
Takahashi, Yoshiko Avila, Susana Correa, Silvia Cardone, Karina Fernández, Mariana Crudo, Favio Sato, Miho Aiga, Hirotsugu Hirayama, Kenji Perez, Freddy Periago, Maria Victoria |
author |
Takahashi, Yoshiko |
author_facet |
Takahashi, Yoshiko Avila, Susana Correa, Silvia Cardone, Karina Fernández, Mariana Crudo, Favio Sato, Miho Aiga, Hirotsugu Hirayama, Kenji Perez, Freddy Periago, Maria Victoria |
author_role |
author |
author2 |
Avila, Susana Correa, Silvia Cardone, Karina Fernández, Mariana Crudo, Favio Sato, Miho Aiga, Hirotsugu Hirayama, Kenji Perez, Freddy Periago, Maria Victoria |
author2_role |
author author author author author author author author author author |
dc.subject.none.fl_str_mv |
TRYPANOSOMA CRUZI CHAGAS DISEASE HEPATITIS B MOTHER-TO-CHILD TRANSMISSION GRAN CHACO PREGNANT WOMEN EMTCT PLUS |
topic |
TRYPANOSOMA CRUZI CHAGAS DISEASE HEPATITIS B MOTHER-TO-CHILD TRANSMISSION GRAN CHACO PREGNANT WOMEN EMTCT PLUS |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Background Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T. cruzi and hepatitis B. The study further attempted to identify the barriers to and facilitators for preventing MTCT of T. cruzi and HBV in the Gran Chaco region of Argentina and Paraguay. Methods Data on T. cruzi and HBV screening and treatment among pregnant women and infants were collected from antenatal care (ANC) registries between June 2018 and December 2022. A cascade-of-care analysis was applied to assess the intervention’s effectiveness and identify bottlenecks. Additionally, key informant interviews were conducted for both implementors and service recipients to identify barriers to and facilitators for accessing screening and treatment using the Consolidated Framework for Implementation Research. Results A total of 1,658 pregnant women were recruited, achieving 100% antenatal care coverage and screening for T. cruzi and HBV. The prevalence of T. cruzi among pregnant women was 3.3% (95%CI: 2.4-4.1%), while in newborns it was 14.0% (95% CI: 6.0–25.0). Treatment coverage for newborns infected with T. cruzi was 100%, whereas postdelivery treatment coverage among mothers was 67.3%. This achievement was likely attributed to strong community engagement, contributing to 100% ANC coverage. However, barriers such as a fragile local health system, long-term follow-up requirements, high mobile populations, cultural beliefs, and social trauma were identified in target areas. Fil: Takahashi, Yoshiko. Nagasaki University; Japón. Niigata University of Health and Welfare; Japón Fil: Avila, Susana. Fundación Mundo Sano; Argentina Fil: Correa, Silvia. Universidad Nacional de Salta; Argentina Fil: Cardone, Karina. Fundación Mundo Sano; Argentina Fil: Fernández, Mariana. Fundación Mundo Sano; Argentina Fil: Crudo, Favio. Fundación Mundo Sano; Argentina Fil: Sato, Miho. Nagasaki University; Japón Fil: Aiga, Hirotsugu. Nagasaki University; Japón Fil: Hirayama, Kenji. Nagasaki University; Japón Fil: Perez, Freddy. Organizacion Mundial de la Salud; Argentina. Universidade Federal de Ciências da Saúde de Porto Alegre; Brasil Fil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; Argentina |
description |
Background Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T. cruzi and hepatitis B. The study further attempted to identify the barriers to and facilitators for preventing MTCT of T. cruzi and HBV in the Gran Chaco region of Argentina and Paraguay. Methods Data on T. cruzi and HBV screening and treatment among pregnant women and infants were collected from antenatal care (ANC) registries between June 2018 and December 2022. A cascade-of-care analysis was applied to assess the intervention’s effectiveness and identify bottlenecks. Additionally, key informant interviews were conducted for both implementors and service recipients to identify barriers to and facilitators for accessing screening and treatment using the Consolidated Framework for Implementation Research. Results A total of 1,658 pregnant women were recruited, achieving 100% antenatal care coverage and screening for T. cruzi and HBV. The prevalence of T. cruzi among pregnant women was 3.3% (95%CI: 2.4-4.1%), while in newborns it was 14.0% (95% CI: 6.0–25.0). Treatment coverage for newborns infected with T. cruzi was 100%, whereas postdelivery treatment coverage among mothers was 67.3%. This achievement was likely attributed to strong community engagement, contributing to 100% ANC coverage. However, barriers such as a fragile local health system, long-term follow-up requirements, high mobile populations, cultural beliefs, and social trauma were identified in target areas. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-12 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/251716 Takahashi, Yoshiko; Avila, Susana; Correa, Silvia; Cardone, Karina; Fernández, Mariana; et al.; Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR); BioMed Central; BMC Primary Care; 25; 1; 12-2024; 1-10 2731-4553 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/251716 |
identifier_str_mv |
Takahashi, Yoshiko; Avila, Susana; Correa, Silvia; Cardone, Karina; Fernández, Mariana; et al.; Barriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: A qualitative analysis using the consolidated framework for implementation research (CFIR); BioMed Central; BMC Primary Care; 25; 1; 12-2024; 1-10 2731-4553 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://bmcprimcare.biomedcentral.com/articles/10.1186/s12875-024-02683-z info:eu-repo/semantics/altIdentifier/doi/10.1186/s12875-024-02683-z |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
BioMed Central |
publisher.none.fl_str_mv |
BioMed Central |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613090895724544 |
score |
13.070432 |