Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos

Autores
Castañaga, Luis Alfredo; Asorey, Cynthia M.; Sandoval, María Teresa; Perez Coll, Cristina Silvia; Argibay, Teresa I.; Herkovits, Jorge
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The adverse effects of ultraviolet B radiation from 547.2 to 30,096 J/m2 on morphogenesis, cell differentiation, and lethality of amphibian embryos at six developmental stages were evaluated from 24 up to 168 h postexposure. The ultraviolet B radiation lethal dose 10, 50, and 90 values were obtained for all developmental stages evaluated. The lethal dose 50 values, considered as the dose causing lethality in the 50% of the organisms exposed, in J/m2 at 168 h postexposure, ranged from 2,307 to 18,930; gill circulation and blastula were the most susceptible and resistant stages, respectively. Ultraviolet B radiation caused malformations in all developmental stages but was significantly more teratogenic at the gill circulation and complete operculum stages. Moreover, at the gill circulation stage, even the lowest dose (547.2 J/m2) resulted in malformations to 100% of embryos. The most common malformations were persistent yolk plug, bifid spine, reduced body size, delayed development, asymmetry, microcephaly and anencephaly, tail and body flexures toward the irradiated side, agenesia or partial gill development, abnormal pigment distribution, and hypermotility. The stage-dependent susceptibility to ultraviolet B radiation during amphibian embryogenesis could be explained in the framework of evoecotoxicology, considering ontogenic features as biomarkers of environmental signatures of living forms ancestors during the evolutionary process. The stage-dependent susceptibility to ultraviolet B radiation on Rhinella (Bufo) arenarum embryos for both lethal and teratogenic effects could contribute to a better understanding of the role of the increased ultraviolet B radiation on worldwide amphibian populations decline.
Fil: Castañaga, Luis Alfredo. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Asorey, Cynthia M.. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina
Fil: Sandoval, María Teresa. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina
Fil: Perez Coll, Cristina Silvia. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Argibay, Teresa I.. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina
Fil: Herkovits, Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina
Materia
ECOTOXICOLOGY
UVB
AMPHIBIAN EMBRYOS
EVOLUTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/243331
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/243331
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryosCastañaga, Luis AlfredoAsorey, Cynthia M.Sandoval, María TeresaPerez Coll, Cristina SilviaArgibay, Teresa I.Herkovits, JorgeECOTOXICOLOGYUVBAMPHIBIAN EMBRYOSEVOLUTIONhttps://purl.org/becyt/ford/1.5https://purl.org/becyt/ford/1The adverse effects of ultraviolet B radiation from 547.2 to 30,096 J/m2 on morphogenesis, cell differentiation, and lethality of amphibian embryos at six developmental stages were evaluated from 24 up to 168 h postexposure. The ultraviolet B radiation lethal dose 10, 50, and 90 values were obtained for all developmental stages evaluated. The lethal dose 50 values, considered as the dose causing lethality in the 50% of the organisms exposed, in J/m2 at 168 h postexposure, ranged from 2,307 to 18,930; gill circulation and blastula were the most susceptible and resistant stages, respectively. Ultraviolet B radiation caused malformations in all developmental stages but was significantly more teratogenic at the gill circulation and complete operculum stages. Moreover, at the gill circulation stage, even the lowest dose (547.2 J/m2) resulted in malformations to 100% of embryos. The most common malformations were persistent yolk plug, bifid spine, reduced body size, delayed development, asymmetry, microcephaly and anencephaly, tail and body flexures toward the irradiated side, agenesia or partial gill development, abnormal pigment distribution, and hypermotility. The stage-dependent susceptibility to ultraviolet B radiation during amphibian embryogenesis could be explained in the framework of evoecotoxicology, considering ontogenic features as biomarkers of environmental signatures of living forms ancestors during the evolutionary process. The stage-dependent susceptibility to ultraviolet B radiation on Rhinella (Bufo) arenarum embryos for both lethal and teratogenic effects could contribute to a better understanding of the role of the increased ultraviolet B radiation on worldwide amphibian populations decline.Fil: Castañaga, Luis Alfredo. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Asorey, Cynthia M.. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; ArgentinaFil: Sandoval, María Teresa. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; ArgentinaFil: Perez Coll, Cristina Silvia. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Argibay, Teresa I.. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; ArgentinaFil: Herkovits, Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; ArgentinaSociety of Environmental Toxicology and Chemistry2009-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/243331Castañaga, Luis Alfredo; Asorey, Cynthia M.; Sandoval, María Teresa; Perez Coll, Cristina Silvia; Argibay, Teresa I.; et al.; Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos; Society of Environmental Toxicology and Chemistry; Environmental Toxicology and Chemistry; 28; 2; 2-2009; 427-4330730-7268CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://setac.onlinelibrary.wiley.com/doi/full/10.1897/08-144.1info:eu-repo/semantics/altIdentifier/doi/10.1897/08-144.1info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:05:16Zoai:ri.conicet.gov.ar:11336/243331instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:05:17.107CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos
title Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos
spellingShingle Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos
Castañaga, Luis Alfredo
ECOTOXICOLOGY
UVB
AMPHIBIAN EMBRYOS
EVOLUTION
title_short Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos
title_full Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos
title_fullStr Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos
title_full_unstemmed Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos
title_sort Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos
dc.creator.none.fl_str_mv Castañaga, Luis Alfredo
Asorey, Cynthia M.
Sandoval, María Teresa
Perez Coll, Cristina Silvia
Argibay, Teresa I.
Herkovits, Jorge
author Castañaga, Luis Alfredo
author_facet Castañaga, Luis Alfredo
Asorey, Cynthia M.
Sandoval, María Teresa
Perez Coll, Cristina Silvia
Argibay, Teresa I.
Herkovits, Jorge
author_role author
author2 Asorey, Cynthia M.
Sandoval, María Teresa
Perez Coll, Cristina Silvia
Argibay, Teresa I.
Herkovits, Jorge
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ECOTOXICOLOGY
UVB
AMPHIBIAN EMBRYOS
EVOLUTION
topic ECOTOXICOLOGY
UVB
AMPHIBIAN EMBRYOS
EVOLUTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.5
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The adverse effects of ultraviolet B radiation from 547.2 to 30,096 J/m2 on morphogenesis, cell differentiation, and lethality of amphibian embryos at six developmental stages were evaluated from 24 up to 168 h postexposure. The ultraviolet B radiation lethal dose 10, 50, and 90 values were obtained for all developmental stages evaluated. The lethal dose 50 values, considered as the dose causing lethality in the 50% of the organisms exposed, in J/m2 at 168 h postexposure, ranged from 2,307 to 18,930; gill circulation and blastula were the most susceptible and resistant stages, respectively. Ultraviolet B radiation caused malformations in all developmental stages but was significantly more teratogenic at the gill circulation and complete operculum stages. Moreover, at the gill circulation stage, even the lowest dose (547.2 J/m2) resulted in malformations to 100% of embryos. The most common malformations were persistent yolk plug, bifid spine, reduced body size, delayed development, asymmetry, microcephaly and anencephaly, tail and body flexures toward the irradiated side, agenesia or partial gill development, abnormal pigment distribution, and hypermotility. The stage-dependent susceptibility to ultraviolet B radiation during amphibian embryogenesis could be explained in the framework of evoecotoxicology, considering ontogenic features as biomarkers of environmental signatures of living forms ancestors during the evolutionary process. The stage-dependent susceptibility to ultraviolet B radiation on Rhinella (Bufo) arenarum embryos for both lethal and teratogenic effects could contribute to a better understanding of the role of the increased ultraviolet B radiation on worldwide amphibian populations decline.
Fil: Castañaga, Luis Alfredo. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Asorey, Cynthia M.. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina
Fil: Sandoval, María Teresa. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina
Fil: Perez Coll, Cristina Silvia. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Argibay, Teresa I.. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina
Fil: Herkovits, Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Pro Salud y Medio Ambiente. Instituto de Ciencias Ambientales y Salud; Argentina
description The adverse effects of ultraviolet B radiation from 547.2 to 30,096 J/m2 on morphogenesis, cell differentiation, and lethality of amphibian embryos at six developmental stages were evaluated from 24 up to 168 h postexposure. The ultraviolet B radiation lethal dose 10, 50, and 90 values were obtained for all developmental stages evaluated. The lethal dose 50 values, considered as the dose causing lethality in the 50% of the organisms exposed, in J/m2 at 168 h postexposure, ranged from 2,307 to 18,930; gill circulation and blastula were the most susceptible and resistant stages, respectively. Ultraviolet B radiation caused malformations in all developmental stages but was significantly more teratogenic at the gill circulation and complete operculum stages. Moreover, at the gill circulation stage, even the lowest dose (547.2 J/m2) resulted in malformations to 100% of embryos. The most common malformations were persistent yolk plug, bifid spine, reduced body size, delayed development, asymmetry, microcephaly and anencephaly, tail and body flexures toward the irradiated side, agenesia or partial gill development, abnormal pigment distribution, and hypermotility. The stage-dependent susceptibility to ultraviolet B radiation during amphibian embryogenesis could be explained in the framework of evoecotoxicology, considering ontogenic features as biomarkers of environmental signatures of living forms ancestors during the evolutionary process. The stage-dependent susceptibility to ultraviolet B radiation on Rhinella (Bufo) arenarum embryos for both lethal and teratogenic effects could contribute to a better understanding of the role of the increased ultraviolet B radiation on worldwide amphibian populations decline.
publishDate 2009
dc.date.none.fl_str_mv 2009-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/243331
Castañaga, Luis Alfredo; Asorey, Cynthia M.; Sandoval, María Teresa; Perez Coll, Cristina Silvia; Argibay, Teresa I.; et al.; Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos; Society of Environmental Toxicology and Chemistry; Environmental Toxicology and Chemistry; 28; 2; 2-2009; 427-433
0730-7268
CONICET Digital
CONICET
url http://hdl.handle.net/11336/243331
identifier_str_mv Castañaga, Luis Alfredo; Asorey, Cynthia M.; Sandoval, María Teresa; Perez Coll, Cristina Silvia; Argibay, Teresa I.; et al.; Stage‐dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo ) arenarum embryos; Society of Environmental Toxicology and Chemistry; Environmental Toxicology and Chemistry; 28; 2; 2-2009; 427-433
0730-7268
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://setac.onlinelibrary.wiley.com/doi/full/10.1897/08-144.1
info:eu-repo/semantics/altIdentifier/doi/10.1897/08-144.1
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Society of Environmental Toxicology and Chemistry
publisher.none.fl_str_mv Society of Environmental Toxicology and Chemistry
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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