Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons

Autores
Acerbo, Martín J.; Gargiulo, Pascual Angel; Krug, Inés; Delius, Juan A.
Año de publicación
2002
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Upon systemic administration of apomorphine, a potent dopamine agonist, pigeons show a bout of pecking behaviour. When the drug is repeatedly administered a sensitization takes place that is associated with pronounced discrimination learning. Here we show that intra-cerebral injections of apomorphine in the periphery of the nucleus accumbens of pigeons also elicit pecking. We additionally show that injections of 5-amino-phosphonohepatnoic acid, a NMDA-glutamate receptor blocker, into the Acc impairs the performance of a learned visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area.
Fil: Acerbo, Martín J.. Universität Konstanz; Alemania
Fil: Gargiulo, Pascual Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Fil: Krug, Inés. Universitat Konstanz; Alemania
Fil: Delius, Juan A.. Universitat Konstanz; Alemania
Materia
DOPAMINE AGONIST
GLUTAMATE ANTAGONISTS
LEARNED DISCRIMINATION
NUCLEUS ACCUMBENS
PECKING RESPONSE
PIGEON
SCHIZOPHRENIA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/127534
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeonsAcerbo, Martín J.Gargiulo, Pascual AngelKrug, InésDelius, Juan A.DOPAMINE AGONISTGLUTAMATE ANTAGONISTSLEARNED DISCRIMINATIONNUCLEUS ACCUMBENSPECKING RESPONSEPIGEONSCHIZOPHRENIAhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Upon systemic administration of apomorphine, a potent dopamine agonist, pigeons show a bout of pecking behaviour. When the drug is repeatedly administered a sensitization takes place that is associated with pronounced discrimination learning. Here we show that intra-cerebral injections of apomorphine in the periphery of the nucleus accumbens of pigeons also elicit pecking. We additionally show that injections of 5-amino-phosphonohepatnoic acid, a NMDA-glutamate receptor blocker, into the Acc impairs the performance of a learned visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area.Fil: Acerbo, Martín J.. Universität Konstanz; AlemaniaFil: Gargiulo, Pascual Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; ArgentinaFil: Krug, Inés. Universitat Konstanz; AlemaniaFil: Delius, Juan A.. Universitat Konstanz; AlemaniaElsevier Science2002-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/127534Acerbo, Martín J.; Gargiulo, Pascual Angel; Krug, Inés; Delius, Juan A.; Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons; Elsevier Science; Behavioural Brain Research; 136; 1; 10-2002; 171-1770166-4328CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/S0166-4328(02)00109-2info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0166432802001092info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:36:46Zoai:ri.conicet.gov.ar:11336/127534instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:36:46.684CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
title Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
spellingShingle Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
Acerbo, Martín J.
DOPAMINE AGONIST
GLUTAMATE ANTAGONISTS
LEARNED DISCRIMINATION
NUCLEUS ACCUMBENS
PECKING RESPONSE
PIGEON
SCHIZOPHRENIA
title_short Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
title_full Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
title_fullStr Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
title_full_unstemmed Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
title_sort Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
dc.creator.none.fl_str_mv Acerbo, Martín J.
Gargiulo, Pascual Angel
Krug, Inés
Delius, Juan A.
author Acerbo, Martín J.
author_facet Acerbo, Martín J.
Gargiulo, Pascual Angel
Krug, Inés
Delius, Juan A.
author_role author
author2 Gargiulo, Pascual Angel
Krug, Inés
Delius, Juan A.
author2_role author
author
author
dc.subject.none.fl_str_mv DOPAMINE AGONIST
GLUTAMATE ANTAGONISTS
LEARNED DISCRIMINATION
NUCLEUS ACCUMBENS
PECKING RESPONSE
PIGEON
SCHIZOPHRENIA
topic DOPAMINE AGONIST
GLUTAMATE ANTAGONISTS
LEARNED DISCRIMINATION
NUCLEUS ACCUMBENS
PECKING RESPONSE
PIGEON
SCHIZOPHRENIA
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Upon systemic administration of apomorphine, a potent dopamine agonist, pigeons show a bout of pecking behaviour. When the drug is repeatedly administered a sensitization takes place that is associated with pronounced discrimination learning. Here we show that intra-cerebral injections of apomorphine in the periphery of the nucleus accumbens of pigeons also elicit pecking. We additionally show that injections of 5-amino-phosphonohepatnoic acid, a NMDA-glutamate receptor blocker, into the Acc impairs the performance of a learned visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area.
Fil: Acerbo, Martín J.. Universität Konstanz; Alemania
Fil: Gargiulo, Pascual Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina
Fil: Krug, Inés. Universitat Konstanz; Alemania
Fil: Delius, Juan A.. Universitat Konstanz; Alemania
description Upon systemic administration of apomorphine, a potent dopamine agonist, pigeons show a bout of pecking behaviour. When the drug is repeatedly administered a sensitization takes place that is associated with pronounced discrimination learning. Here we show that intra-cerebral injections of apomorphine in the periphery of the nucleus accumbens of pigeons also elicit pecking. We additionally show that injections of 5-amino-phosphonohepatnoic acid, a NMDA-glutamate receptor blocker, into the Acc impairs the performance of a learned visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area.
publishDate 2002
dc.date.none.fl_str_mv 2002-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/127534
Acerbo, Martín J.; Gargiulo, Pascual Angel; Krug, Inés; Delius, Juan A.; Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons; Elsevier Science; Behavioural Brain Research; 136; 1; 10-2002; 171-177
0166-4328
CONICET Digital
CONICET
url http://hdl.handle.net/11336/127534
identifier_str_mv Acerbo, Martín J.; Gargiulo, Pascual Angel; Krug, Inés; Delius, Juan A.; Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons; Elsevier Science; Behavioural Brain Research; 136; 1; 10-2002; 171-177
0166-4328
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/S0166-4328(02)00109-2
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0166432802001092
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083490114699264
score 13.22299

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