Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences

Autores
Gorustovich Alonso, Alejandro Adrian; Roether, Judith A.; Boccaccini, Aldo R.
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The incorporation of bioactive glass into bone tissue-engineered scaffolds can be widely beneficial based on emerging evidence in the literature about the angiogenic potential of this material, particularly 45S5 Bioglass . This article reviews the literature discussing in vitro studies which have demonstrated that increases in angiogenic indicators have been achieved through both direct and indirect contact of relevant cells with 45S5 Bioglass particles or with their dissolution products. A few available in vivo studies confirming the ability of bioactive glass, incorporated into scaffolds, to stimulate neovascularization are also discussed. Suggestions for further research are given, highlighting the need for specific investigations designed to assess the effect of particular ion dissolution products from bioactive glasses and their relative concentration on angiogenesis both in vitro and in vivo.
Fil: Gorustovich Alonso, Alejandro Adrian. Comision Nacional de Energia Atomica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Roether, Judith A.. Imperial College London; Reino Unido
Fil: Boccaccini, Aldo R.. Imperial College London; Reino Unido
Materia
Bioactive Glasses
Angiogenesis
Regenerative Medicine
Tissue Engineering
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/14091
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/14091
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidencesGorustovich Alonso, Alejandro AdrianRoether, Judith A.Boccaccini, Aldo R.Bioactive GlassesAngiogenesisRegenerative MedicineTissue Engineeringhttps://purl.org/becyt/ford/3.4https://purl.org/becyt/ford/3The incorporation of bioactive glass into bone tissue-engineered scaffolds can be widely beneficial based on emerging evidence in the literature about the angiogenic potential of this material, particularly 45S5 Bioglass . This article reviews the literature discussing in vitro studies which have demonstrated that increases in angiogenic indicators have been achieved through both direct and indirect contact of relevant cells with 45S5 Bioglass particles or with their dissolution products. A few available in vivo studies confirming the ability of bioactive glass, incorporated into scaffolds, to stimulate neovascularization are also discussed. Suggestions for further research are given, highlighting the need for specific investigations designed to assess the effect of particular ion dissolution products from bioactive glasses and their relative concentration on angiogenesis both in vitro and in vivo.Fil: Gorustovich Alonso, Alejandro Adrian. Comision Nacional de Energia Atomica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Roether, Judith A.. Imperial College London; Reino UnidoFil: Boccaccini, Aldo R.. Imperial College London; Reino UnidoMary Ann Liebert Inc2010-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/14091Gorustovich Alonso, Alejandro Adrian; Roether, Judith A.; Boccaccini, Aldo R.; Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences; Mary Ann Liebert Inc; Tissue Engineering Part B-reviews; 16; 2; 12-2010; 199-2071937-3368enginfo:eu-repo/semantics/altIdentifier/doi/10.1089/ten.teb.2009.0416info:eu-repo/semantics/altIdentifier/url/http://online.liebertpub.com/doi/abs/10.1089/ten.teb.2009.0416info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:11:07Zoai:ri.conicet.gov.ar:11336/14091instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:11:08.03CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences
title Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences
spellingShingle Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences
Gorustovich Alonso, Alejandro Adrian
Bioactive Glasses
Angiogenesis
Regenerative Medicine
Tissue Engineering
title_short Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences
title_full Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences
title_fullStr Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences
title_full_unstemmed Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences
title_sort Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences
dc.creator.none.fl_str_mv Gorustovich Alonso, Alejandro Adrian
Roether, Judith A.
Boccaccini, Aldo R.
author Gorustovich Alonso, Alejandro Adrian
author_facet Gorustovich Alonso, Alejandro Adrian
Roether, Judith A.
Boccaccini, Aldo R.
author_role author
author2 Roether, Judith A.
Boccaccini, Aldo R.
author2_role author
author
dc.subject.none.fl_str_mv Bioactive Glasses
Angiogenesis
Regenerative Medicine
Tissue Engineering
topic Bioactive Glasses
Angiogenesis
Regenerative Medicine
Tissue Engineering
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.4
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The incorporation of bioactive glass into bone tissue-engineered scaffolds can be widely beneficial based on emerging evidence in the literature about the angiogenic potential of this material, particularly 45S5 Bioglass . This article reviews the literature discussing in vitro studies which have demonstrated that increases in angiogenic indicators have been achieved through both direct and indirect contact of relevant cells with 45S5 Bioglass particles or with their dissolution products. A few available in vivo studies confirming the ability of bioactive glass, incorporated into scaffolds, to stimulate neovascularization are also discussed. Suggestions for further research are given, highlighting the need for specific investigations designed to assess the effect of particular ion dissolution products from bioactive glasses and their relative concentration on angiogenesis both in vitro and in vivo.
Fil: Gorustovich Alonso, Alejandro Adrian. Comision Nacional de Energia Atomica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Roether, Judith A.. Imperial College London; Reino Unido
Fil: Boccaccini, Aldo R.. Imperial College London; Reino Unido
description The incorporation of bioactive glass into bone tissue-engineered scaffolds can be widely beneficial based on emerging evidence in the literature about the angiogenic potential of this material, particularly 45S5 Bioglass . This article reviews the literature discussing in vitro studies which have demonstrated that increases in angiogenic indicators have been achieved through both direct and indirect contact of relevant cells with 45S5 Bioglass particles or with their dissolution products. A few available in vivo studies confirming the ability of bioactive glass, incorporated into scaffolds, to stimulate neovascularization are also discussed. Suggestions for further research are given, highlighting the need for specific investigations designed to assess the effect of particular ion dissolution products from bioactive glasses and their relative concentration on angiogenesis both in vitro and in vivo.
publishDate 2010
dc.date.none.fl_str_mv 2010-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/14091
Gorustovich Alonso, Alejandro Adrian; Roether, Judith A.; Boccaccini, Aldo R.; Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences; Mary Ann Liebert Inc; Tissue Engineering Part B-reviews; 16; 2; 12-2010; 199-207
1937-3368
url http://hdl.handle.net/11336/14091
identifier_str_mv Gorustovich Alonso, Alejandro Adrian; Roether, Judith A.; Boccaccini, Aldo R.; Effect of bioactive glasses on Angiogenesis: a review of in vitro and in vivo evidences; Mary Ann Liebert Inc; Tissue Engineering Part B-reviews; 16; 2; 12-2010; 199-207
1937-3368
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1089/ten.teb.2009.0416
info:eu-repo/semantics/altIdentifier/url/http://online.liebertpub.com/doi/abs/10.1089/ten.teb.2009.0416
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Mary Ann Liebert Inc
publisher.none.fl_str_mv Mary Ann Liebert Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614007677255680
score 13.070432

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