45S5 bio-glass flame spheroidization: Chemical composition and bioactivity

Autores
Verón, María Gisela; Rivera Figueroa, Edison; Prado, Miguel Oscar
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
45S5 bioglass microspheres are very attractive in the biomedical field, as they have the ability to stimulate and guide bone and soft tissue regeneration. One of the main factors influencing the success of these materials is their chemical composition. Therefore, knowing the effect of the microsphere synthesis method on this composition is extremely important. In this work, microspheres with a diameter distribution of 35-150 µm were prepared from a bio-glass with the composition 45S5 using the flame spheroidization method. Their bioactivity was studied in simulated biological fluid (SBF) at 37 ºC. An important loss in the concentration of Na and P was detected in the spheroidization process, reaching 85% and 73%, respectively, in microspheres smaller than 65 µm. The P distribution was heterogeneous. These modifications affected the early stages of the hydroxyapatite formation mechanism, delaying its deposition on the surface of the microspheres with respect to the parent bio-glass.
Fil: Verón, María Gisela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina
Fil: Rivera Figueroa, Edison. Universidad del Valle; Colombia
Fil: Prado, Miguel Oscar. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina
Materia
BIOACTIVE GLASS
MICROESPHERES
HYDROXYAPATITE
TISSUE ENGINEERING
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/272757
Acceder
id CONICETDig_0c134fa1302d5bdcaa57207b95841a0a
oai_identifier_str oai:ri.conicet.gov.ar:11336/272757
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling 45S5 bio-glass flame spheroidization: Chemical composition and bioactivityVerón, María GiselaRivera Figueroa, EdisonPrado, Miguel OscarBIOACTIVE GLASSMICROESPHERESHYDROXYAPATITETISSUE ENGINEERINGhttps://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/245S5 bioglass microspheres are very attractive in the biomedical field, as they have the ability to stimulate and guide bone and soft tissue regeneration. One of the main factors influencing the success of these materials is their chemical composition. Therefore, knowing the effect of the microsphere synthesis method on this composition is extremely important. In this work, microspheres with a diameter distribution of 35-150 µm were prepared from a bio-glass with the composition 45S5 using the flame spheroidization method. Their bioactivity was studied in simulated biological fluid (SBF) at 37 ºC. An important loss in the concentration of Na and P was detected in the spheroidization process, reaching 85% and 73%, respectively, in microspheres smaller than 65 µm. The P distribution was heterogeneous. These modifications affected the early stages of the hydroxyapatite formation mechanism, delaying its deposition on the surface of the microspheres with respect to the parent bio-glass.Fil: Verón, María Gisela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; ArgentinaFil: Rivera Figueroa, Edison. Universidad del Valle; ColombiaFil: Prado, Miguel Oscar. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; ArgentinaAssociação Brasileira de Cerâmica2025-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/272757Verón, María Gisela; Rivera Figueroa, Edison; Prado, Miguel Oscar; 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity; Associação Brasileira de Cerâmica; Ceramica; 71; 3-2025; 1-100366-69131678-4553CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.scielo.br/j/ce/a/nNfC36HTb59V93Nn5BnSJjP/?format=html&lang=eninfo:eu-repo/semantics/altIdentifier/doi/10.1590/RUCJ5814info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:21:40Zoai:ri.conicet.gov.ar:11336/272757instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:21:40.936CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity
title 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity
spellingShingle 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity
Verón, María Gisela
BIOACTIVE GLASS
MICROESPHERES
HYDROXYAPATITE
TISSUE ENGINEERING
title_short 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity
title_full 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity
title_fullStr 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity
title_full_unstemmed 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity
title_sort 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity
dc.creator.none.fl_str_mv Verón, María Gisela
Rivera Figueroa, Edison
Prado, Miguel Oscar
author Verón, María Gisela
author_facet Verón, María Gisela
Rivera Figueroa, Edison
Prado, Miguel Oscar
author_role author
author2 Rivera Figueroa, Edison
Prado, Miguel Oscar
author2_role author
author
dc.subject.none.fl_str_mv BIOACTIVE GLASS
MICROESPHERES
HYDROXYAPATITE
TISSUE ENGINEERING
topic BIOACTIVE GLASS
MICROESPHERES
HYDROXYAPATITE
TISSUE ENGINEERING
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv 45S5 bioglass microspheres are very attractive in the biomedical field, as they have the ability to stimulate and guide bone and soft tissue regeneration. One of the main factors influencing the success of these materials is their chemical composition. Therefore, knowing the effect of the microsphere synthesis method on this composition is extremely important. In this work, microspheres with a diameter distribution of 35-150 µm were prepared from a bio-glass with the composition 45S5 using the flame spheroidization method. Their bioactivity was studied in simulated biological fluid (SBF) at 37 ºC. An important loss in the concentration of Na and P was detected in the spheroidization process, reaching 85% and 73%, respectively, in microspheres smaller than 65 µm. The P distribution was heterogeneous. These modifications affected the early stages of the hydroxyapatite formation mechanism, delaying its deposition on the surface of the microspheres with respect to the parent bio-glass.
Fil: Verón, María Gisela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina
Fil: Rivera Figueroa, Edison. Universidad del Valle; Colombia
Fil: Prado, Miguel Oscar. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina
description 45S5 bioglass microspheres are very attractive in the biomedical field, as they have the ability to stimulate and guide bone and soft tissue regeneration. One of the main factors influencing the success of these materials is their chemical composition. Therefore, knowing the effect of the microsphere synthesis method on this composition is extremely important. In this work, microspheres with a diameter distribution of 35-150 µm were prepared from a bio-glass with the composition 45S5 using the flame spheroidization method. Their bioactivity was studied in simulated biological fluid (SBF) at 37 ºC. An important loss in the concentration of Na and P was detected in the spheroidization process, reaching 85% and 73%, respectively, in microspheres smaller than 65 µm. The P distribution was heterogeneous. These modifications affected the early stages of the hydroxyapatite formation mechanism, delaying its deposition on the surface of the microspheres with respect to the parent bio-glass.
publishDate 2025
dc.date.none.fl_str_mv 2025-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/272757
Verón, María Gisela; Rivera Figueroa, Edison; Prado, Miguel Oscar; 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity; Associação Brasileira de Cerâmica; Ceramica; 71; 3-2025; 1-10
0366-6913
1678-4553
CONICET Digital
CONICET
url http://hdl.handle.net/11336/272757
identifier_str_mv Verón, María Gisela; Rivera Figueroa, Edison; Prado, Miguel Oscar; 45S5 bio-glass flame spheroidization: Chemical composition and bioactivity; Associação Brasileira de Cerâmica; Ceramica; 71; 3-2025; 1-10
0366-6913
1678-4553
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.scielo.br/j/ce/a/nNfC36HTb59V93Nn5BnSJjP/?format=html&lang=en
info:eu-repo/semantics/altIdentifier/doi/10.1590/RUCJ5814
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Cerâmica
publisher.none.fl_str_mv Associação Brasileira de Cerâmica
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781723583447040
score 12.982451

Publicaciones similares