Monitoring of Ivermectin residues in bovine and pig tissues

Autores
Cantón, Lucila; Cantón, Candela; Dominguez, Maria Paula; Farias, Cristina Elena; Alvarez, Luis Ignacio; Lanusse, Carlos Edmundo; Moreno Torrejon, Laura
Año de publicación
2024
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Argentina is traditionally a beef-producing country. However, in recent years, pig production has grown exponentially. Due to technological advancements and economic factors, consumer preferences have shifted. Animal production systems are closely linked to the use of veterinary drugs for the prevention, control, or treatment of parasitic diseases. Consequently, if good agricultural practices are not followed, products from these productions could contain residues above the Maximum Residue Limits (MRLs). In this context, ivermectin (IVM) is one of the most widely used drugs to treat parasitic diseases. This study aims to conduct an exposure assessment and risk characterization for IVM residues in bovine and pig tissues intended for local consumption in Buenos Aires province (Argentina). Anonymous surveys were conducted to determine the population´s consumption habits. Additionally, samples of beef, bovine fat, bovine liver, bovine kidney, pig meat, and pig fat were collected. The samples were analyzed by HPLC with a fluorescence detector. Considering that the tissues involved are not consumed raw, the stability of IVM residues during boiling, grilling, and baking was evaluated. Finally, using @Risk software, IVM prevalence, residue concentrations, residue stability during cooking, and bovine and pig tissue consumption were modeled to predict the probability of consuming tissues with IVM residues above the Acceptable Daily Intake (ADI). Of the 691 samples analyzed, 13.7% had quantifiable drug residue levels, and1.9% had residue concentrations exceeding the MRL. The mean IVM concentrations (range) were 42.18 (0.11–587.15), 31.66 (2.96–283.33), 162.61 (1.32–516.55), 22.78 (1.51–65.40), 15.26 (0.07–194.25), and 22.14 ppb (1.58–126.76) for beef, bovine fat, bovine liver, bovine kidney, pig meat, and pig fat, respectively. Although cooking methods did not destroy IVM residues, fortunately, the probability of consuming bovine and pig tissues with IVM residues above the ADI was negligible. Therefore, IVM residues in tissues did not represent a risk to consumer health.
Fil: Cantón, Lucila. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Cantón, Candela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Dominguez, Maria Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Farias, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Alvarez, Luis Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Lanusse, Carlos Edmundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Moreno Torrejon, Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
XXVII Congreso Panamericano de Ciencias Veterinarias
Montevideo
Uruguay
Colegio de Veterinarios del Uruguay
Universidad de la República. Facultad de Ciencias Veterinarias
Materia
IVERMECTIN RESIDUES
EXPOSURE ASSESSMENT
PIG TISSUES
BOVINE TISSUES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/257732
Acceder
id CONICETDig_85d1badd000166a029b36b9da5833484
oai_identifier_str oai:ri.conicet.gov.ar:11336/257732
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Monitoring of Ivermectin residues in bovine and pig tissuesCantón, LucilaCantón, CandelaDominguez, Maria PaulaFarias, Cristina ElenaAlvarez, Luis IgnacioLanusse, Carlos EdmundoMoreno Torrejon, LauraIVERMECTIN RESIDUESEXPOSURE ASSESSMENTPIG TISSUESBOVINE TISSUEShttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Argentina is traditionally a beef-producing country. However, in recent years, pig production has grown exponentially. Due to technological advancements and economic factors, consumer preferences have shifted. Animal production systems are closely linked to the use of veterinary drugs for the prevention, control, or treatment of parasitic diseases. Consequently, if good agricultural practices are not followed, products from these productions could contain residues above the Maximum Residue Limits (MRLs). In this context, ivermectin (IVM) is one of the most widely used drugs to treat parasitic diseases. This study aims to conduct an exposure assessment and risk characterization for IVM residues in bovine and pig tissues intended for local consumption in Buenos Aires province (Argentina). Anonymous surveys were conducted to determine the population´s consumption habits. Additionally, samples of beef, bovine fat, bovine liver, bovine kidney, pig meat, and pig fat were collected. The samples were analyzed by HPLC with a fluorescence detector. Considering that the tissues involved are not consumed raw, the stability of IVM residues during boiling, grilling, and baking was evaluated. Finally, using @Risk software, IVM prevalence, residue concentrations, residue stability during cooking, and bovine and pig tissue consumption were modeled to predict the probability of consuming tissues with IVM residues above the Acceptable Daily Intake (ADI). Of the 691 samples analyzed, 13.7% had quantifiable drug residue levels, and1.9% had residue concentrations exceeding the MRL. The mean IVM concentrations (range) were 42.18 (0.11–587.15), 31.66 (2.96–283.33), 162.61 (1.32–516.55), 22.78 (1.51–65.40), 15.26 (0.07–194.25), and 22.14 ppb (1.58–126.76) for beef, bovine fat, bovine liver, bovine kidney, pig meat, and pig fat, respectively. Although cooking methods did not destroy IVM residues, fortunately, the probability of consuming bovine and pig tissues with IVM residues above the ADI was negligible. Therefore, IVM residues in tissues did not represent a risk to consumer health.Fil: Cantón, Lucila. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Cantón, Candela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Dominguez, Maria Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Farias, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Alvarez, Luis Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Lanusse, Carlos Edmundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Moreno Torrejon, Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaXXVII Congreso Panamericano de Ciencias VeterinariasMontevideoUruguayColegio de Veterinarios del UruguayUniversidad de la República. Facultad de Ciencias VeterinariasColegio de Veterinarios del Uruguay2024info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/257732Monitoring of Ivermectin residues in bovine and pig tissues; XXVII Congreso Panamericano de Ciencias Veterinarias; Montevideo; Uruguay; 2024; 407CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.panvet2024.uy/ https://www.panvet2024.uy/_files/ugd/d0b038_3e3bd8f2500f4eba967245d820276927.pdfinfo:eu-repo/semantics/altIdentifier/url/https://www.panvet2024.uy/Internacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:07Zoai:ri.conicet.gov.ar:11336/257732instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:07.779CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Monitoring of Ivermectin residues in bovine and pig tissues
title Monitoring of Ivermectin residues in bovine and pig tissues
spellingShingle Monitoring of Ivermectin residues in bovine and pig tissues
Cantón, Lucila
IVERMECTIN RESIDUES
EXPOSURE ASSESSMENT
PIG TISSUES
BOVINE TISSUES
title_short Monitoring of Ivermectin residues in bovine and pig tissues
title_full Monitoring of Ivermectin residues in bovine and pig tissues
title_fullStr Monitoring of Ivermectin residues in bovine and pig tissues
title_full_unstemmed Monitoring of Ivermectin residues in bovine and pig tissues
title_sort Monitoring of Ivermectin residues in bovine and pig tissues
dc.creator.none.fl_str_mv Cantón, Lucila
Cantón, Candela
Dominguez, Maria Paula
Farias, Cristina Elena
Alvarez, Luis Ignacio
Lanusse, Carlos Edmundo
Moreno Torrejon, Laura
author Cantón, Lucila
author_facet Cantón, Lucila
Cantón, Candela
Dominguez, Maria Paula
Farias, Cristina Elena
Alvarez, Luis Ignacio
Lanusse, Carlos Edmundo
Moreno Torrejon, Laura
author_role author
author2 Cantón, Candela
Dominguez, Maria Paula
Farias, Cristina Elena
Alvarez, Luis Ignacio
Lanusse, Carlos Edmundo
Moreno Torrejon, Laura
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv IVERMECTIN RESIDUES
EXPOSURE ASSESSMENT
PIG TISSUES
BOVINE TISSUES
topic IVERMECTIN RESIDUES
EXPOSURE ASSESSMENT
PIG TISSUES
BOVINE TISSUES
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Argentina is traditionally a beef-producing country. However, in recent years, pig production has grown exponentially. Due to technological advancements and economic factors, consumer preferences have shifted. Animal production systems are closely linked to the use of veterinary drugs for the prevention, control, or treatment of parasitic diseases. Consequently, if good agricultural practices are not followed, products from these productions could contain residues above the Maximum Residue Limits (MRLs). In this context, ivermectin (IVM) is one of the most widely used drugs to treat parasitic diseases. This study aims to conduct an exposure assessment and risk characterization for IVM residues in bovine and pig tissues intended for local consumption in Buenos Aires province (Argentina). Anonymous surveys were conducted to determine the population´s consumption habits. Additionally, samples of beef, bovine fat, bovine liver, bovine kidney, pig meat, and pig fat were collected. The samples were analyzed by HPLC with a fluorescence detector. Considering that the tissues involved are not consumed raw, the stability of IVM residues during boiling, grilling, and baking was evaluated. Finally, using @Risk software, IVM prevalence, residue concentrations, residue stability during cooking, and bovine and pig tissue consumption were modeled to predict the probability of consuming tissues with IVM residues above the Acceptable Daily Intake (ADI). Of the 691 samples analyzed, 13.7% had quantifiable drug residue levels, and1.9% had residue concentrations exceeding the MRL. The mean IVM concentrations (range) were 42.18 (0.11–587.15), 31.66 (2.96–283.33), 162.61 (1.32–516.55), 22.78 (1.51–65.40), 15.26 (0.07–194.25), and 22.14 ppb (1.58–126.76) for beef, bovine fat, bovine liver, bovine kidney, pig meat, and pig fat, respectively. Although cooking methods did not destroy IVM residues, fortunately, the probability of consuming bovine and pig tissues with IVM residues above the ADI was negligible. Therefore, IVM residues in tissues did not represent a risk to consumer health.
Fil: Cantón, Lucila. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Cantón, Candela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Dominguez, Maria Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Farias, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Alvarez, Luis Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Lanusse, Carlos Edmundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Moreno Torrejon, Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
XXVII Congreso Panamericano de Ciencias Veterinarias
Montevideo
Uruguay
Colegio de Veterinarios del Uruguay
Universidad de la República. Facultad de Ciencias Veterinarias
description Argentina is traditionally a beef-producing country. However, in recent years, pig production has grown exponentially. Due to technological advancements and economic factors, consumer preferences have shifted. Animal production systems are closely linked to the use of veterinary drugs for the prevention, control, or treatment of parasitic diseases. Consequently, if good agricultural practices are not followed, products from these productions could contain residues above the Maximum Residue Limits (MRLs). In this context, ivermectin (IVM) is one of the most widely used drugs to treat parasitic diseases. This study aims to conduct an exposure assessment and risk characterization for IVM residues in bovine and pig tissues intended for local consumption in Buenos Aires province (Argentina). Anonymous surveys were conducted to determine the population´s consumption habits. Additionally, samples of beef, bovine fat, bovine liver, bovine kidney, pig meat, and pig fat were collected. The samples were analyzed by HPLC with a fluorescence detector. Considering that the tissues involved are not consumed raw, the stability of IVM residues during boiling, grilling, and baking was evaluated. Finally, using @Risk software, IVM prevalence, residue concentrations, residue stability during cooking, and bovine and pig tissue consumption were modeled to predict the probability of consuming tissues with IVM residues above the Acceptable Daily Intake (ADI). Of the 691 samples analyzed, 13.7% had quantifiable drug residue levels, and1.9% had residue concentrations exceeding the MRL. The mean IVM concentrations (range) were 42.18 (0.11–587.15), 31.66 (2.96–283.33), 162.61 (1.32–516.55), 22.78 (1.51–65.40), 15.26 (0.07–194.25), and 22.14 ppb (1.58–126.76) for beef, bovine fat, bovine liver, bovine kidney, pig meat, and pig fat, respectively. Although cooking methods did not destroy IVM residues, fortunately, the probability of consuming bovine and pig tissues with IVM residues above the ADI was negligible. Therefore, IVM residues in tissues did not represent a risk to consumer health.
publishDate 2024
dc.date.none.fl_str_mv 2024
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Congreso
Book
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/257732
Monitoring of Ivermectin residues in bovine and pig tissues; XXVII Congreso Panamericano de Ciencias Veterinarias; Montevideo; Uruguay; 2024; 407
CONICET Digital
CONICET
url http://hdl.handle.net/11336/257732
identifier_str_mv Monitoring of Ivermectin residues in bovine and pig tissues; XXVII Congreso Panamericano de Ciencias Veterinarias; Montevideo; Uruguay; 2024; 407
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.panvet2024.uy/ https://www.panvet2024.uy/_files/ugd/d0b038_3e3bd8f2500f4eba967245d820276927.pdf
info:eu-repo/semantics/altIdentifier/url/https://www.panvet2024.uy/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv Colegio de Veterinarios del Uruguay
publisher.none.fl_str_mv Colegio de Veterinarios del Uruguay
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842268646400851968
score 13.13397

Publicaciones similares