A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality

Autores
Gallo, Loreana Carolina; Ramírez Rigo, María Veronica; Piña, Juliana; Bucala, Veronica
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the manufacture of herbal medicinal tablets, dried plant extracts are employed as the therapeutic ingredient. These powders, usually obtained by spray drying, are typically hygroscopic and possess poor flow and compactability for the manufacture of tablets by direct compression (DC). Besides, spray-drying operating conditions and liquid feed composition are reported to be dependent on the herbal medicine. Consequently, the production of dried extractsimplies long new product development times. Therefore, the goal of this paper was to: a) provide recommendations as initial production point of herbal powders suitable for DC by spray drying and b) study the powder properties to identify those that are affected by the extract nature. Particularly, a unique set of operating conditions was found to be appropriate to produce powders of seven different medicinal plant extracts. In fact, all the spray-dried products showed adequate flowability, stability and compactability.Powders properties, as particle size and morphology, moisture content, hygroscopicity, flowability and compact hardness were not a function of the type of herb. Conversely, the process yields and glass transition temperature, particle and bulk densities, powder composition, compact porosity, wetting and disintegration times were found to be dependent on the chemical nature of the herbs.
Fil: Gallo, Loreana Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia; Argentina
Fil: Ramírez Rigo, María Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia; Argentina
Fil: Piña, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Bucala, Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Materia
Spray Drying
Herbal Medicinal Extracts
Tablets
Direct Compression
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/25023
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/25023
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product qualityGallo, Loreana CarolinaRamírez Rigo, María VeronicaPiña, JulianaBucala, VeronicaSpray DryingHerbal Medicinal ExtractsTabletsDirect Compressionhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2In the manufacture of herbal medicinal tablets, dried plant extracts are employed as the therapeutic ingredient. These powders, usually obtained by spray drying, are typically hygroscopic and possess poor flow and compactability for the manufacture of tablets by direct compression (DC). Besides, spray-drying operating conditions and liquid feed composition are reported to be dependent on the herbal medicine. Consequently, the production of dried extractsimplies long new product development times. Therefore, the goal of this paper was to: a) provide recommendations as initial production point of herbal powders suitable for DC by spray drying and b) study the powder properties to identify those that are affected by the extract nature. Particularly, a unique set of operating conditions was found to be appropriate to produce powders of seven different medicinal plant extracts. In fact, all the spray-dried products showed adequate flowability, stability and compactability.Powders properties, as particle size and morphology, moisture content, hygroscopicity, flowability and compact hardness were not a function of the type of herb. Conversely, the process yields and glass transition temperature, particle and bulk densities, powder composition, compact porosity, wetting and disintegration times were found to be dependent on the chemical nature of the herbs.Fil: Gallo, Loreana Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia; ArgentinaFil: Ramírez Rigo, María Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia; ArgentinaFil: Piña, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Bucala, Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaElsevier2015-10-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/25023Gallo, Loreana Carolina; Ramírez Rigo, María Veronica; Piña, Juliana; Bucala, Veronica; A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality; Elsevier; Chemical Engineering Research & Design; 104; 23-10-2015; 681-6940263-8762CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.cherd.2015.10.009info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0263876215003834info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:01:02Zoai:ri.conicet.gov.ar:11336/25023instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:01:02.754CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality
title A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality
spellingShingle A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality
Gallo, Loreana Carolina
Spray Drying
Herbal Medicinal Extracts
Tablets
Direct Compression
title_short A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality
title_full A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality
title_fullStr A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality
title_full_unstemmed A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality
title_sort A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality
dc.creator.none.fl_str_mv Gallo, Loreana Carolina
Ramírez Rigo, María Veronica
Piña, Juliana
Bucala, Veronica
author Gallo, Loreana Carolina
author_facet Gallo, Loreana Carolina
Ramírez Rigo, María Veronica
Piña, Juliana
Bucala, Veronica
author_role author
author2 Ramírez Rigo, María Veronica
Piña, Juliana
Bucala, Veronica
author2_role author
author
author
dc.subject.none.fl_str_mv Spray Drying
Herbal Medicinal Extracts
Tablets
Direct Compression
topic Spray Drying
Herbal Medicinal Extracts
Tablets
Direct Compression
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv In the manufacture of herbal medicinal tablets, dried plant extracts are employed as the therapeutic ingredient. These powders, usually obtained by spray drying, are typically hygroscopic and possess poor flow and compactability for the manufacture of tablets by direct compression (DC). Besides, spray-drying operating conditions and liquid feed composition are reported to be dependent on the herbal medicine. Consequently, the production of dried extractsimplies long new product development times. Therefore, the goal of this paper was to: a) provide recommendations as initial production point of herbal powders suitable for DC by spray drying and b) study the powder properties to identify those that are affected by the extract nature. Particularly, a unique set of operating conditions was found to be appropriate to produce powders of seven different medicinal plant extracts. In fact, all the spray-dried products showed adequate flowability, stability and compactability.Powders properties, as particle size and morphology, moisture content, hygroscopicity, flowability and compact hardness were not a function of the type of herb. Conversely, the process yields and glass transition temperature, particle and bulk densities, powder composition, compact porosity, wetting and disintegration times were found to be dependent on the chemical nature of the herbs.
Fil: Gallo, Loreana Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia; Argentina
Fil: Ramírez Rigo, María Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia; Argentina
Fil: Piña, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Bucala, Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
description In the manufacture of herbal medicinal tablets, dried plant extracts are employed as the therapeutic ingredient. These powders, usually obtained by spray drying, are typically hygroscopic and possess poor flow and compactability for the manufacture of tablets by direct compression (DC). Besides, spray-drying operating conditions and liquid feed composition are reported to be dependent on the herbal medicine. Consequently, the production of dried extractsimplies long new product development times. Therefore, the goal of this paper was to: a) provide recommendations as initial production point of herbal powders suitable for DC by spray drying and b) study the powder properties to identify those that are affected by the extract nature. Particularly, a unique set of operating conditions was found to be appropriate to produce powders of seven different medicinal plant extracts. In fact, all the spray-dried products showed adequate flowability, stability and compactability.Powders properties, as particle size and morphology, moisture content, hygroscopicity, flowability and compact hardness were not a function of the type of herb. Conversely, the process yields and glass transition temperature, particle and bulk densities, powder composition, compact porosity, wetting and disintegration times were found to be dependent on the chemical nature of the herbs.
publishDate 2015
dc.date.none.fl_str_mv 2015-10-23
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/25023
Gallo, Loreana Carolina; Ramírez Rigo, María Veronica; Piña, Juliana; Bucala, Veronica; A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality; Elsevier; Chemical Engineering Research & Design; 104; 23-10-2015; 681-694
0263-8762
CONICET Digital
CONICET
url http://hdl.handle.net/11336/25023
identifier_str_mv Gallo, Loreana Carolina; Ramírez Rigo, María Veronica; Piña, Juliana; Bucala, Veronica; A comparative study of spray-dried medicinal plant aqueous extracts: Drying performance and product quality; Elsevier; Chemical Engineering Research & Design; 104; 23-10-2015; 681-694
0263-8762
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.cherd.2015.10.009
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0263876215003834
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269672778498048
score 13.13397

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