Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock

Autores
Oates, Andrew C.; Morelli, Luis Guillermo; Ares, Saúl
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the precursors of the segmented vertebral column. Understanding how the rhythmic signal arises, how it achieves precision and how it patterns the embryo remain challenging issues. Recent work has provided evidence of how the period of the segmentation clock is regulated and how this affects the anatomy of the embryo. The ongoing development of realtime clock reporters and mathematical models promise novel insight into the dynamic behavior of the clock. © 2012. Published by The Company of Biologists Ltd.
Fil: Oates, Andrew C.. Max Planck Institute Of Molecular Cell Biology And Genetics; Alemania
Fil: Morelli, Luis Guillermo. Max Planck Institute Of Molecular Cell Biology And Genetics; Alemania. Universidad de Buenos Aires; Argentina
Fil: Ares, Saúl. Max Planck Institute For The Physics Of Complex Systems; Alemania
Materia
GRADIENT
MODELING
NEGATIVE FEEDBACK
OSCILLATOR
SIGNALING
SOMITOGENESIS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/55642
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/55642
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clockOates, Andrew C.Morelli, Luis GuillermoAres, SaúlGRADIENTMODELINGNEGATIVE FEEDBACKOSCILLATORSIGNALINGSOMITOGENESIShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the precursors of the segmented vertebral column. Understanding how the rhythmic signal arises, how it achieves precision and how it patterns the embryo remain challenging issues. Recent work has provided evidence of how the period of the segmentation clock is regulated and how this affects the anatomy of the embryo. The ongoing development of realtime clock reporters and mathematical models promise novel insight into the dynamic behavior of the clock. © 2012. Published by The Company of Biologists Ltd.Fil: Oates, Andrew C.. Max Planck Institute Of Molecular Cell Biology And Genetics; AlemaniaFil: Morelli, Luis Guillermo. Max Planck Institute Of Molecular Cell Biology And Genetics; Alemania. Universidad de Buenos Aires; ArgentinaFil: Ares, Saúl. Max Planck Institute For The Physics Of Complex Systems; AlemaniaCompany of Biologists2012-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/55642Oates, Andrew C.; Morelli, Luis Guillermo; Ares, Saúl; Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock; Company of Biologists; Development; 139; 4; 1-2012; 625-6390950-1991CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://dev.biologists.org/content/139/4/625info:eu-repo/semantics/altIdentifier/doi/10.1242/dev.063735info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:46:00Zoai:ri.conicet.gov.ar:11336/55642instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:46:00.347CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
title Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
spellingShingle Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
Oates, Andrew C.
GRADIENT
MODELING
NEGATIVE FEEDBACK
OSCILLATOR
SIGNALING
SOMITOGENESIS
title_short Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
title_full Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
title_fullStr Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
title_full_unstemmed Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
title_sort Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
dc.creator.none.fl_str_mv Oates, Andrew C.
Morelli, Luis Guillermo
Ares, Saúl
author Oates, Andrew C.
author_facet Oates, Andrew C.
Morelli, Luis Guillermo
Ares, Saúl
author_role author
author2 Morelli, Luis Guillermo
Ares, Saúl
author2_role author
author
dc.subject.none.fl_str_mv GRADIENT
MODELING
NEGATIVE FEEDBACK
OSCILLATOR
SIGNALING
SOMITOGENESIS
topic GRADIENT
MODELING
NEGATIVE FEEDBACK
OSCILLATOR
SIGNALING
SOMITOGENESIS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the precursors of the segmented vertebral column. Understanding how the rhythmic signal arises, how it achieves precision and how it patterns the embryo remain challenging issues. Recent work has provided evidence of how the period of the segmentation clock is regulated and how this affects the anatomy of the embryo. The ongoing development of realtime clock reporters and mathematical models promise novel insight into the dynamic behavior of the clock. © 2012. Published by The Company of Biologists Ltd.
Fil: Oates, Andrew C.. Max Planck Institute Of Molecular Cell Biology And Genetics; Alemania
Fil: Morelli, Luis Guillermo. Max Planck Institute Of Molecular Cell Biology And Genetics; Alemania. Universidad de Buenos Aires; Argentina
Fil: Ares, Saúl. Max Planck Institute For The Physics Of Complex Systems; Alemania
description The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the precursors of the segmented vertebral column. Understanding how the rhythmic signal arises, how it achieves precision and how it patterns the embryo remain challenging issues. Recent work has provided evidence of how the period of the segmentation clock is regulated and how this affects the anatomy of the embryo. The ongoing development of realtime clock reporters and mathematical models promise novel insight into the dynamic behavior of the clock. © 2012. Published by The Company of Biologists Ltd.
publishDate 2012
dc.date.none.fl_str_mv 2012-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/55642
Oates, Andrew C.; Morelli, Luis Guillermo; Ares, Saúl; Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock; Company of Biologists; Development; 139; 4; 1-2012; 625-639
0950-1991
CONICET Digital
CONICET
url http://hdl.handle.net/11336/55642
identifier_str_mv Oates, Andrew C.; Morelli, Luis Guillermo; Ares, Saúl; Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock; Company of Biologists; Development; 139; 4; 1-2012; 625-639
0950-1991
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://dev.biologists.org/content/139/4/625
info:eu-repo/semantics/altIdentifier/doi/10.1242/dev.063735
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Company of Biologists
publisher.none.fl_str_mv Company of Biologists
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613436809412608
score 13.070432

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