Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS

Autores
Permigiani, Isis Sabrina; Vallejo Azar, Nicolás Karim; Hasuoka, Paul Emir; Gil, Raul Andres; Romero, Maria Carolina
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Imitation milks based on vegetables have become relevant in recent years as a substitute for cow´s milk. Total and inorganic content of arsenic (As) determination in food is of utmost importance due to toxicological concerns. This study aimed to (1) optimize and validate a methodology for speciation analysis using anion exchange high performance liquid chromatography coupled to plasma mass spectrometry and (2) analyze the arsenic content in milk and imitation milks.Determination of As (III) and As (V) was done following a simple and innovative treatment, which consisted on the dilution of a small volume of sample in mobile phase and further filtration. Furthermore, acid microdigestion for total As determination with small amounts of acid and sample was optimized. The detection limits of the method ranged from 0.2 to 0.7 µg L-1. Regarding to arsenic content we found that imitation milks based on peanuts and nuts presented the lowest inorganic As content (between 1.7 to 1 µg L-1) whereas the highest values were found in imitations based on soy, rice and vetch (27.3, 13 and 8 µg L-1, respectively). The cow’s milk presented intermediate levels of inorganic As (4 µg L-1). Also, almond- and quinoa-based imitation milks showed inorganic As values below detection limits, so these imitation milks may be the safest to consume with respect to arsenic content
Fil: Permigiani, Isis Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; Argentina
Fil: Vallejo Azar, Nicolás Karim. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Hasuoka, Paul Emir. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Gil, Raul Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Romero, Maria Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; Argentina
Materia
Milk and imitation milks
trace elements
HPLC-ICP-MS analysis
Microdigestion procedure
Nivel de accesibilidad
acceso embargado
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/229762
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MSPermigiani, Isis SabrinaVallejo Azar, Nicolás KarimHasuoka, Paul EmirGil, Raul AndresRomero, Maria CarolinaMilk and imitation milkstrace elementsHPLC-ICP-MS analysisMicrodigestion procedurehttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Imitation milks based on vegetables have become relevant in recent years as a substitute for cow´s milk. Total and inorganic content of arsenic (As) determination in food is of utmost importance due to toxicological concerns. This study aimed to (1) optimize and validate a methodology for speciation analysis using anion exchange high performance liquid chromatography coupled to plasma mass spectrometry and (2) analyze the arsenic content in milk and imitation milks.Determination of As (III) and As (V) was done following a simple and innovative treatment, which consisted on the dilution of a small volume of sample in mobile phase and further filtration. Furthermore, acid microdigestion for total As determination with small amounts of acid and sample was optimized. The detection limits of the method ranged from 0.2 to 0.7 µg L-1. Regarding to arsenic content we found that imitation milks based on peanuts and nuts presented the lowest inorganic As content (between 1.7 to 1 µg L-1) whereas the highest values were found in imitations based on soy, rice and vetch (27.3, 13 and 8 µg L-1, respectively). The cow’s milk presented intermediate levels of inorganic As (4 µg L-1). Also, almond- and quinoa-based imitation milks showed inorganic As values below detection limits, so these imitation milks may be the safest to consume with respect to arsenic contentFil: Permigiani, Isis Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; ArgentinaFil: Vallejo Azar, Nicolás Karim. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Hasuoka, Paul Emir. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Gil, Raul Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Romero, Maria Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; ArgentinaAcademic Press Inc Elsevier Science2023-12info:eu-repo/date/embargoEnd/2024-06-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/229762Permigiani, Isis Sabrina; Vallejo Azar, Nicolás Karim; Hasuoka, Paul Emir; Gil, Raul Andres; Romero, Maria Carolina; Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS; Academic Press Inc Elsevier Science; Journal of Food Composition and Analysis; 126; 12-2023; 1-310889-1575CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S088915752300772Xinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jfca.2023.105898info:eu-repo/semantics/embargoedAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:44:55Zoai:ri.conicet.gov.ar:11336/229762instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:44:55.796CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS
title Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS
spellingShingle Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS
Permigiani, Isis Sabrina
Milk and imitation milks
trace elements
HPLC-ICP-MS analysis
Microdigestion procedure
title_short Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS
title_full Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS
title_fullStr Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS
title_full_unstemmed Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS
title_sort Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS
dc.creator.none.fl_str_mv Permigiani, Isis Sabrina
Vallejo Azar, Nicolás Karim
Hasuoka, Paul Emir
Gil, Raul Andres
Romero, Maria Carolina
author Permigiani, Isis Sabrina
author_facet Permigiani, Isis Sabrina
Vallejo Azar, Nicolás Karim
Hasuoka, Paul Emir
Gil, Raul Andres
Romero, Maria Carolina
author_role author
author2 Vallejo Azar, Nicolás Karim
Hasuoka, Paul Emir
Gil, Raul Andres
Romero, Maria Carolina
author2_role author
author
author
author
dc.subject.none.fl_str_mv Milk and imitation milks
trace elements
HPLC-ICP-MS analysis
Microdigestion procedure
topic Milk and imitation milks
trace elements
HPLC-ICP-MS analysis
Microdigestion procedure
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Imitation milks based on vegetables have become relevant in recent years as a substitute for cow´s milk. Total and inorganic content of arsenic (As) determination in food is of utmost importance due to toxicological concerns. This study aimed to (1) optimize and validate a methodology for speciation analysis using anion exchange high performance liquid chromatography coupled to plasma mass spectrometry and (2) analyze the arsenic content in milk and imitation milks.Determination of As (III) and As (V) was done following a simple and innovative treatment, which consisted on the dilution of a small volume of sample in mobile phase and further filtration. Furthermore, acid microdigestion for total As determination with small amounts of acid and sample was optimized. The detection limits of the method ranged from 0.2 to 0.7 µg L-1. Regarding to arsenic content we found that imitation milks based on peanuts and nuts presented the lowest inorganic As content (between 1.7 to 1 µg L-1) whereas the highest values were found in imitations based on soy, rice and vetch (27.3, 13 and 8 µg L-1, respectively). The cow’s milk presented intermediate levels of inorganic As (4 µg L-1). Also, almond- and quinoa-based imitation milks showed inorganic As values below detection limits, so these imitation milks may be the safest to consume with respect to arsenic content
Fil: Permigiani, Isis Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; Argentina
Fil: Vallejo Azar, Nicolás Karim. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Hasuoka, Paul Emir. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Gil, Raul Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Romero, Maria Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; Argentina
description Imitation milks based on vegetables have become relevant in recent years as a substitute for cow´s milk. Total and inorganic content of arsenic (As) determination in food is of utmost importance due to toxicological concerns. This study aimed to (1) optimize and validate a methodology for speciation analysis using anion exchange high performance liquid chromatography coupled to plasma mass spectrometry and (2) analyze the arsenic content in milk and imitation milks.Determination of As (III) and As (V) was done following a simple and innovative treatment, which consisted on the dilution of a small volume of sample in mobile phase and further filtration. Furthermore, acid microdigestion for total As determination with small amounts of acid and sample was optimized. The detection limits of the method ranged from 0.2 to 0.7 µg L-1. Regarding to arsenic content we found that imitation milks based on peanuts and nuts presented the lowest inorganic As content (between 1.7 to 1 µg L-1) whereas the highest values were found in imitations based on soy, rice and vetch (27.3, 13 and 8 µg L-1, respectively). The cow’s milk presented intermediate levels of inorganic As (4 µg L-1). Also, almond- and quinoa-based imitation milks showed inorganic As values below detection limits, so these imitation milks may be the safest to consume with respect to arsenic content
publishDate 2023
dc.date.none.fl_str_mv 2023-12
info:eu-repo/date/embargoEnd/2024-06-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/229762
Permigiani, Isis Sabrina; Vallejo Azar, Nicolás Karim; Hasuoka, Paul Emir; Gil, Raul Andres; Romero, Maria Carolina; Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS; Academic Press Inc Elsevier Science; Journal of Food Composition and Analysis; 126; 12-2023; 1-31
0889-1575
CONICET Digital
CONICET
url http://hdl.handle.net/11336/229762
identifier_str_mv Permigiani, Isis Sabrina; Vallejo Azar, Nicolás Karim; Hasuoka, Paul Emir; Gil, Raul Andres; Romero, Maria Carolina; Arsenic speciation analysis in cow's milk and plant-based imitation milks by HPLC-ICP-MS; Academic Press Inc Elsevier Science; Journal of Food Composition and Analysis; 126; 12-2023; 1-31
0889-1575
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S088915752300772X
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jfca.2023.105898
dc.rights.none.fl_str_mv info:eu-repo/semantics/embargoedAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv embargoedAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Academic Press Inc Elsevier Science
publisher.none.fl_str_mv Academic Press Inc Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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