Integration of melanopsin signals into visual pathways

Autores
Barrionuevo, Pablo Alejandro; Cao, Dingcai
Año de publicación
2019
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Anatomical studies showed that melanopsin-containing ipRGCs project to the LGN, however, how melanopsin photopigment activation integrates into the Magnocellular (MC), Parvocellular (PC) and Koniocellular (KC) pathways is not understood. To study this, we have implemented three approaches, including natural image statistics analysis, pupillary recordings, and psychophysical testing. Principal component analysis of nine hyperspectral images revealed that optimal combinations of photoreceptors involved intrusion of melanopsin signals in the three postreceptoral pathways. Flickering pupillary recordings (1Hz) showed melanopsin activation combines linearly in the MC and KC pathways but nonlinearly in the PC pathway. Psychophysical testing showed melanopsin modulations of sinusoidal temporal contrast sensitivity, especially of the MC pathway at 3Hz for 2000 td. Our results demonstrated that all three visual pathways are affected by melanopsin activation but in different fashion and extent.
Fil: Barrionuevo, Pablo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Investigación en Luz, Ambiente y Visión. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Instituto de Investigación en Luz, Ambiente y Visión; Argentina
Fil: Cao, Dingcai. University Of Illinois; Estados Unidos
41st European Conference on Visual Perception
Trieste
Italia
Universidad de Trieste
Materia
MELANOPSIN
VISION
PSYCHOPHYSICS
PUPIL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/276897
Acceder
id CONICETDig_6c11d6b05560a99e7ccd3ae3fc1f1f6e
oai_identifier_str oai:ri.conicet.gov.ar:11336/276897
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Integration of melanopsin signals into visual pathwaysBarrionuevo, Pablo AlejandroCao, DingcaiMELANOPSINVISIONPSYCHOPHYSICSPUPILhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Anatomical studies showed that melanopsin-containing ipRGCs project to the LGN, however, how melanopsin photopigment activation integrates into the Magnocellular (MC), Parvocellular (PC) and Koniocellular (KC) pathways is not understood. To study this, we have implemented three approaches, including natural image statistics analysis, pupillary recordings, and psychophysical testing. Principal component analysis of nine hyperspectral images revealed that optimal combinations of photoreceptors involved intrusion of melanopsin signals in the three postreceptoral pathways. Flickering pupillary recordings (1Hz) showed melanopsin activation combines linearly in the MC and KC pathways but nonlinearly in the PC pathway. Psychophysical testing showed melanopsin modulations of sinusoidal temporal contrast sensitivity, especially of the MC pathway at 3Hz for 2000 td. Our results demonstrated that all three visual pathways are affected by melanopsin activation but in different fashion and extent.Fil: Barrionuevo, Pablo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Investigación en Luz, Ambiente y Visión. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Instituto de Investigación en Luz, Ambiente y Visión; ArgentinaFil: Cao, Dingcai. University Of Illinois; Estados Unidos41st European Conference on Visual PerceptionTriesteItaliaUniversidad de TriesteSAGE Publications2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectConferenciaJournalhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/276897Integration of melanopsin signals into visual pathways; 41st European Conference on Visual Perception; Trieste; Italia; 2018; 5-50301-00661468-4233CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.1177/0301006618824879info:eu-repo/semantics/altIdentifier/doi/10.1177/0301006618824879Internacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-12-23T13:26:13Zoai:ri.conicet.gov.ar:11336/276897instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-12-23 13:26:13.954CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Integration of melanopsin signals into visual pathways
title Integration of melanopsin signals into visual pathways
spellingShingle Integration of melanopsin signals into visual pathways
Barrionuevo, Pablo Alejandro
MELANOPSIN
VISION
PSYCHOPHYSICS
PUPIL
title_short Integration of melanopsin signals into visual pathways
title_full Integration of melanopsin signals into visual pathways
title_fullStr Integration of melanopsin signals into visual pathways
title_full_unstemmed Integration of melanopsin signals into visual pathways
title_sort Integration of melanopsin signals into visual pathways
dc.creator.none.fl_str_mv Barrionuevo, Pablo Alejandro
Cao, Dingcai
author Barrionuevo, Pablo Alejandro
author_facet Barrionuevo, Pablo Alejandro
Cao, Dingcai
author_role author
author2 Cao, Dingcai
author2_role author
dc.subject.none.fl_str_mv MELANOPSIN
VISION
PSYCHOPHYSICS
PUPIL
topic MELANOPSIN
VISION
PSYCHOPHYSICS
PUPIL
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Anatomical studies showed that melanopsin-containing ipRGCs project to the LGN, however, how melanopsin photopigment activation integrates into the Magnocellular (MC), Parvocellular (PC) and Koniocellular (KC) pathways is not understood. To study this, we have implemented three approaches, including natural image statistics analysis, pupillary recordings, and psychophysical testing. Principal component analysis of nine hyperspectral images revealed that optimal combinations of photoreceptors involved intrusion of melanopsin signals in the three postreceptoral pathways. Flickering pupillary recordings (1Hz) showed melanopsin activation combines linearly in the MC and KC pathways but nonlinearly in the PC pathway. Psychophysical testing showed melanopsin modulations of sinusoidal temporal contrast sensitivity, especially of the MC pathway at 3Hz for 2000 td. Our results demonstrated that all three visual pathways are affected by melanopsin activation but in different fashion and extent.
Fil: Barrionuevo, Pablo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Investigación en Luz, Ambiente y Visión. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Instituto de Investigación en Luz, Ambiente y Visión; Argentina
Fil: Cao, Dingcai. University Of Illinois; Estados Unidos
41st European Conference on Visual Perception
Trieste
Italia
Universidad de Trieste
description Anatomical studies showed that melanopsin-containing ipRGCs project to the LGN, however, how melanopsin photopigment activation integrates into the Magnocellular (MC), Parvocellular (PC) and Koniocellular (KC) pathways is not understood. To study this, we have implemented three approaches, including natural image statistics analysis, pupillary recordings, and psychophysical testing. Principal component analysis of nine hyperspectral images revealed that optimal combinations of photoreceptors involved intrusion of melanopsin signals in the three postreceptoral pathways. Flickering pupillary recordings (1Hz) showed melanopsin activation combines linearly in the MC and KC pathways but nonlinearly in the PC pathway. Psychophysical testing showed melanopsin modulations of sinusoidal temporal contrast sensitivity, especially of the MC pathway at 3Hz for 2000 td. Our results demonstrated that all three visual pathways are affected by melanopsin activation but in different fashion and extent.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Conferencia
Journal
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/276897
Integration of melanopsin signals into visual pathways; 41st European Conference on Visual Perception; Trieste; Italia; 2018; 5-5
0301-0066
1468-4233
CONICET Digital
CONICET
url http://hdl.handle.net/11336/276897
identifier_str_mv Integration of melanopsin signals into visual pathways; 41st European Conference on Visual Perception; Trieste; Italia; 2018; 5-5
0301-0066
1468-4233
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://journals.sagepub.com/doi/10.1177/0301006618824879
info:eu-repo/semantics/altIdentifier/doi/10.1177/0301006618824879
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1852335131973386240
score 12.952241

Publicaciones similares