Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion

Autores
Consolini, Alicia Elvira; Bonazzola, Patricia
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Calorimetry has been applied to skeletal and cardiac muscle from many years ago, andthere were intents to calculate the heat fractions associated to basal metabolism (restingheat rate, Hr) and the active heat (Ha). This review explains the principles and evolution of cardiac energetic, measured by calorimetry and the advantages with respect to the measurement of oxygen consumption. Moreover, the methods to estimate separately the fractions of tension-dependent (TDH) and tension-independent heat (TIH) were described, as well as the characterization of each one. A method to determine 4 heat components in a single beat in the presence of contraction in perfused rat ventricles was revised, as well as the properties of the long-duration fourth fraction not previously seen with other methods.The advantages and limitations of each method were analyzed. Calorimetry allows toevaluate the occurrence degree of certain exothermic processes such as ionic fluxes can be studied by comparing the heat released with the energetic equivalent and the stoichiometry of the process with the ATP hydrolysis. Calorimetry is a sensitive and useful methodology to evaluate the ?in situ? incidence of exothermic mechanisms in the heart.
Fil: Consolini, Alicia Elvira. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biológicas; Argentina
Fil: Bonazzola, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Materia
CALORIMETRY
HEART
BASAL METABOLISM
ACTIVE HEAT
TDH AND TDI
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/41991
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/41991
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network_name_str CONICET Digital (CONICET)
spelling Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusionConsolini, Alicia ElviraBonazzola, PatriciaCALORIMETRYHEARTBASAL METABOLISMACTIVE HEATTDH AND TDIhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Calorimetry has been applied to skeletal and cardiac muscle from many years ago, andthere were intents to calculate the heat fractions associated to basal metabolism (restingheat rate, Hr) and the active heat (Ha). This review explains the principles and evolution of cardiac energetic, measured by calorimetry and the advantages with respect to the measurement of oxygen consumption. Moreover, the methods to estimate separately the fractions of tension-dependent (TDH) and tension-independent heat (TIH) were described, as well as the characterization of each one. A method to determine 4 heat components in a single beat in the presence of contraction in perfused rat ventricles was revised, as well as the properties of the long-duration fourth fraction not previously seen with other methods.The advantages and limitations of each method were analyzed. Calorimetry allows toevaluate the occurrence degree of certain exothermic processes such as ionic fluxes can be studied by comparing the heat released with the energetic equivalent and the stoichiometry of the process with the ATP hydrolysis. Calorimetry is a sensitive and useful methodology to evaluate the ?in situ? incidence of exothermic mechanisms in the heart.Fil: Consolini, Alicia Elvira. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biológicas; ArgentinaFil: Bonazzola, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaSociedad Argentina de Fisiología2017-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/41991Consolini, Alicia Elvira; Bonazzola, Patricia; Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion; Sociedad Argentina de Fisiología; Physiological Mini Review; 10; 2; 8-2017; 12-221669-5410CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://pmr.safisiol.org.ar/uploadsarchivos/vol10_n3.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:21Zoai:ri.conicet.gov.ar:11336/41991instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:22.114CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion
title Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion
spellingShingle Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion
Consolini, Alicia Elvira
CALORIMETRY
HEART
BASAL METABOLISM
ACTIVE HEAT
TDH AND TDI
title_short Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion
title_full Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion
title_fullStr Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion
title_full_unstemmed Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion
title_sort Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion
dc.creator.none.fl_str_mv Consolini, Alicia Elvira
Bonazzola, Patricia
author Consolini, Alicia Elvira
author_facet Consolini, Alicia Elvira
Bonazzola, Patricia
author_role author
author2 Bonazzola, Patricia
author2_role author
dc.subject.none.fl_str_mv CALORIMETRY
HEART
BASAL METABOLISM
ACTIVE HEAT
TDH AND TDI
topic CALORIMETRY
HEART
BASAL METABOLISM
ACTIVE HEAT
TDH AND TDI
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Calorimetry has been applied to skeletal and cardiac muscle from many years ago, andthere were intents to calculate the heat fractions associated to basal metabolism (restingheat rate, Hr) and the active heat (Ha). This review explains the principles and evolution of cardiac energetic, measured by calorimetry and the advantages with respect to the measurement of oxygen consumption. Moreover, the methods to estimate separately the fractions of tension-dependent (TDH) and tension-independent heat (TIH) were described, as well as the characterization of each one. A method to determine 4 heat components in a single beat in the presence of contraction in perfused rat ventricles was revised, as well as the properties of the long-duration fourth fraction not previously seen with other methods.The advantages and limitations of each method were analyzed. Calorimetry allows toevaluate the occurrence degree of certain exothermic processes such as ionic fluxes can be studied by comparing the heat released with the energetic equivalent and the stoichiometry of the process with the ATP hydrolysis. Calorimetry is a sensitive and useful methodology to evaluate the ?in situ? incidence of exothermic mechanisms in the heart.
Fil: Consolini, Alicia Elvira. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biológicas; Argentina
Fil: Bonazzola, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
description Calorimetry has been applied to skeletal and cardiac muscle from many years ago, andthere were intents to calculate the heat fractions associated to basal metabolism (restingheat rate, Hr) and the active heat (Ha). This review explains the principles and evolution of cardiac energetic, measured by calorimetry and the advantages with respect to the measurement of oxygen consumption. Moreover, the methods to estimate separately the fractions of tension-dependent (TDH) and tension-independent heat (TIH) were described, as well as the characterization of each one. A method to determine 4 heat components in a single beat in the presence of contraction in perfused rat ventricles was revised, as well as the properties of the long-duration fourth fraction not previously seen with other methods.The advantages and limitations of each method were analyzed. Calorimetry allows toevaluate the occurrence degree of certain exothermic processes such as ionic fluxes can be studied by comparing the heat released with the energetic equivalent and the stoichiometry of the process with the ATP hydrolysis. Calorimetry is a sensitive and useful methodology to evaluate the ?in situ? incidence of exothermic mechanisms in the heart.
publishDate 2017
dc.date.none.fl_str_mv 2017-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/41991
Consolini, Alicia Elvira; Bonazzola, Patricia; Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion; Sociedad Argentina de Fisiología; Physiological Mini Review; 10; 2; 8-2017; 12-22
1669-5410
CONICET Digital
CONICET
url http://hdl.handle.net/11336/41991
identifier_str_mv Consolini, Alicia Elvira; Bonazzola, Patricia; Calorimetry of isolated hearts (ii) energetic of ca 2+ homeostasis in different animal models and during ischemia – reperfusion; Sociedad Argentina de Fisiología; Physiological Mini Review; 10; 2; 8-2017; 12-22
1669-5410
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pmr.safisiol.org.ar/uploadsarchivos/vol10_n3.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedad Argentina de Fisiología
publisher.none.fl_str_mv Sociedad Argentina de Fisiología
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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