Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions

Autores
Consolini, Alicia Elvira; Bonazzola, Patricia
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Calorimetry has been applied to skeletal and cardiac muscle from many years ago, andthere were intents to calculate the heat fractions associated to basal metabolism (restingheat rate, Hr) and the active heat (Ha). This review explains the principles and evolution of cardiac energetic, measured by calorimetry and the advantages with respect to the measurement of oxygen consumption. Moreover, the methods to estimate separately the fractions of tension-dependent (TDH) and tension-independent heat (TIH) were described, as well as the characterization of each one. A method to determine 4 heat components in a single beat in the presence of contraction in perfused rat ventricles was revised, as well as the properties of the long-duration fourth fraction not previously seen with other methods.The advantages and limitations of each method were analyzed. Calorimetry allows toevaluate the occurrence degree of certain exothermic processes such as ionic fluxes can be studied by comparing the heat released with the energetic equivalent and the stoichiometry of the process with the ATP hydrolysis. Calorimetry is a sensitive and useful methodology to evaluate the "in situ" incidence of exothermic mechanisms in the heart.
Facultad de Ciencias Exactas
Materia
Ciencias Médicas
Calorimetry
Heart
Basal metabolism
Active heat
TDH and TIH
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/101276
Acceder
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repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditionsConsolini, Alicia ElviraBonazzola, PatriciaCiencias MédicasCalorimetryHeartBasal metabolismActive heatTDH and TIHCalorimetry has been applied to skeletal and cardiac muscle from many years ago, andthere were intents to calculate the heat fractions associated to basal metabolism (restingheat rate, Hr) and the active heat (Ha). This review explains the principles and evolution of cardiac energetic, measured by calorimetry and the advantages with respect to the measurement of oxygen consumption. Moreover, the methods to estimate separately the fractions of tension-dependent (TDH) and tension-independent heat (TIH) were described, as well as the characterization of each one. A method to determine 4 heat components in a single beat in the presence of contraction in perfused rat ventricles was revised, as well as the properties of the long-duration fourth fraction not previously seen with other methods.The advantages and limitations of each method were analyzed. Calorimetry allows toevaluate the occurrence degree of certain exothermic processes such as ionic fluxes can be studied by comparing the heat released with the energetic equivalent and the stoichiometry of the process with the ATP hydrolysis. Calorimetry is a sensitive and useful methodology to evaluate the "in situ" incidence of exothermic mechanisms in the heart.Facultad de Ciencias Exactas2017-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf12-22http://sedici.unlp.edu.ar/handle/10915/101276enginfo:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/41991info:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/uploadsarchivos/vol10_n2.pdfinfo:eu-repo/semantics/altIdentifier/issn/1669-5410info:eu-repo/semantics/altIdentifier/hdl/11336/41991info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T10:53:15Zoai:sedici.unlp.edu.ar:10915/101276Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 10:53:15.522SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions
title Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions
spellingShingle Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions
Consolini, Alicia Elvira
Ciencias Médicas
Calorimetry
Heart
Basal metabolism
Active heat
TDH and TIH
title_short Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions
title_full Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions
title_fullStr Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions
title_full_unstemmed Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions
title_sort Calorimetry of isolated hearts (I) a method to study the energetic of CA 2+ homeostasis during physiological and pathological conditions
dc.creator.none.fl_str_mv Consolini, Alicia Elvira
Bonazzola, Patricia
author Consolini, Alicia Elvira
author_facet Consolini, Alicia Elvira
Bonazzola, Patricia
author_role author
author2 Bonazzola, Patricia
author2_role author
dc.subject.none.fl_str_mv Ciencias Médicas
Calorimetry
Heart
Basal metabolism
Active heat
TDH and TIH
topic Ciencias Médicas
Calorimetry
Heart
Basal metabolism
Active heat
TDH and TIH
dc.description.none.fl_txt_mv Calorimetry has been applied to skeletal and cardiac muscle from many years ago, andthere were intents to calculate the heat fractions associated to basal metabolism (restingheat rate, Hr) and the active heat (Ha). This review explains the principles and evolution of cardiac energetic, measured by calorimetry and the advantages with respect to the measurement of oxygen consumption. Moreover, the methods to estimate separately the fractions of tension-dependent (TDH) and tension-independent heat (TIH) were described, as well as the characterization of each one. A method to determine 4 heat components in a single beat in the presence of contraction in perfused rat ventricles was revised, as well as the properties of the long-duration fourth fraction not previously seen with other methods.The advantages and limitations of each method were analyzed. Calorimetry allows toevaluate the occurrence degree of certain exothermic processes such as ionic fluxes can be studied by comparing the heat released with the energetic equivalent and the stoichiometry of the process with the ATP hydrolysis. Calorimetry is a sensitive and useful methodology to evaluate the "in situ" incidence of exothermic mechanisms in the heart.
Facultad de Ciencias Exactas
description Calorimetry has been applied to skeletal and cardiac muscle from many years ago, andthere were intents to calculate the heat fractions associated to basal metabolism (restingheat rate, Hr) and the active heat (Ha). This review explains the principles and evolution of cardiac energetic, measured by calorimetry and the advantages with respect to the measurement of oxygen consumption. Moreover, the methods to estimate separately the fractions of tension-dependent (TDH) and tension-independent heat (TIH) were described, as well as the characterization of each one. A method to determine 4 heat components in a single beat in the presence of contraction in perfused rat ventricles was revised, as well as the properties of the long-duration fourth fraction not previously seen with other methods.The advantages and limitations of each method were analyzed. Calorimetry allows toevaluate the occurrence degree of certain exothermic processes such as ionic fluxes can be studied by comparing the heat released with the energetic equivalent and the stoichiometry of the process with the ATP hydrolysis. Calorimetry is a sensitive and useful methodology to evaluate the "in situ" incidence of exothermic mechanisms in the heart.
publishDate 2017
dc.date.none.fl_str_mv 2017-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/101276
url http://sedici.unlp.edu.ar/handle/10915/101276
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/41991
info:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/uploadsarchivos/vol10_n2.pdf
info:eu-repo/semantics/altIdentifier/issn/1669-5410
info:eu-repo/semantics/altIdentifier/hdl/11336/41991
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
12-22
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.13397

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