Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices

Autores
Tarzi, Olga Inés; Di Stéfano, Luciano; Argüello, Juan Elias; Oksdath Mansilla, Gabriela; Erra Balsells, Rosa
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
2,4-, 2,5-, 2,6- and 3,5-dihydroxyacetophenone (DHA) used as matrices in matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) were studied by steady-state and transient absorption spectroscopy, together with DFT calculations at the B3LYP level of theory. All compounds have low fluorescence quantum yields, possibly due to an efficient excited-state intramolecular proton transfer (ESIPT). Laser flash photolysis (LFP) results showed that, only for 2,4-DHA, a phototautomer could be detected at k = 400 nm. Their photochemical stability in solution at different wavelengths and conditions was analyzed by UV–Vis and 1 H nuclear magnetic resonance spectroscopy (1 H-NMR), together with thin layer chromatography and ultraviolet laser desorption/ionization mass spectrometry (UV-LDI-MS). Only 3,5-DHA showed decomposition when irradiated, probably because phototautomerization is not possible. Thermal stability studies of these compounds in solid state were also conducted.
Fil: Tarzi, Olga Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; Argentina
Fil: Di Stéfano, Luciano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; Argentina
Fil: Argüello, Juan Elias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Córdoba. Instituto de Investigaciones en Físicoquímica de Córdoba; Argentina
Fil: Oksdath Mansilla, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Córdoba. Instituto de Investigaciones en Físicoquímica de Córdoba; Argentina
Fil: Erra Balsells, Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; Argentina
Materia
Uv-Maldi-Ms
Fenilketone Matrix
Photochemistry
2-Hidroxy-Ketophenones
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/2103
Acceder
id CONICETDig_58416a8119355af225235356c5f44950
oai_identifier_str oai:ri.conicet.gov.ar:11336/2103
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS MatricesTarzi, Olga InésDi Stéfano, LucianoArgüello, Juan EliasOksdath Mansilla, GabrielaErra Balsells, RosaUv-Maldi-MsFenilketone MatrixPhotochemistry2-Hidroxy-Ketophenoneshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/12,4-, 2,5-, 2,6- and 3,5-dihydroxyacetophenone (DHA) used as matrices in matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) were studied by steady-state and transient absorption spectroscopy, together with DFT calculations at the B3LYP level of theory. All compounds have low fluorescence quantum yields, possibly due to an efficient excited-state intramolecular proton transfer (ESIPT). Laser flash photolysis (LFP) results showed that, only for 2,4-DHA, a phototautomer could be detected at k = 400 nm. Their photochemical stability in solution at different wavelengths and conditions was analyzed by UV–Vis and 1 H nuclear magnetic resonance spectroscopy (1 H-NMR), together with thin layer chromatography and ultraviolet laser desorption/ionization mass spectrometry (UV-LDI-MS). Only 3,5-DHA showed decomposition when irradiated, probably because phototautomerization is not possible. Thermal stability studies of these compounds in solid state were also conducted.Fil: Tarzi, Olga Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Di Stéfano, Luciano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Argüello, Juan Elias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Córdoba. Instituto de Investigaciones en Físicoquímica de Córdoba; ArgentinaFil: Oksdath Mansilla, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Córdoba. Instituto de Investigaciones en Físicoquímica de Córdoba; ArgentinaFil: Erra Balsells, Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; ArgentinaWiley2013-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/2103Tarzi, Olga Inés; Di Stéfano, Luciano; Argüello, Juan Elias; Oksdath Mansilla, Gabriela; Erra Balsells, Rosa; Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices; Wiley; Photochemistry and Photobiology; 89; 6; 11-2013; 1368-13740031-8655enginfo:eu-repo/semantics/altIdentifier/doi/10.1111/php.12130info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/php.12130/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:49:02Zoai:ri.conicet.gov.ar:11336/2103instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:49:02.63CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices
title Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices
spellingShingle Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices
Tarzi, Olga Inés
Uv-Maldi-Ms
Fenilketone Matrix
Photochemistry
2-Hidroxy-Ketophenones
title_short Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices
title_full Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices
title_fullStr Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices
title_full_unstemmed Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices
title_sort Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices
dc.creator.none.fl_str_mv Tarzi, Olga Inés
Di Stéfano, Luciano
Argüello, Juan Elias
Oksdath Mansilla, Gabriela
Erra Balsells, Rosa
author Tarzi, Olga Inés
author_facet Tarzi, Olga Inés
Di Stéfano, Luciano
Argüello, Juan Elias
Oksdath Mansilla, Gabriela
Erra Balsells, Rosa
author_role author
author2 Di Stéfano, Luciano
Argüello, Juan Elias
Oksdath Mansilla, Gabriela
Erra Balsells, Rosa
author2_role author
author
author
author
dc.subject.none.fl_str_mv Uv-Maldi-Ms
Fenilketone Matrix
Photochemistry
2-Hidroxy-Ketophenones
topic Uv-Maldi-Ms
Fenilketone Matrix
Photochemistry
2-Hidroxy-Ketophenones
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv 2,4-, 2,5-, 2,6- and 3,5-dihydroxyacetophenone (DHA) used as matrices in matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) were studied by steady-state and transient absorption spectroscopy, together with DFT calculations at the B3LYP level of theory. All compounds have low fluorescence quantum yields, possibly due to an efficient excited-state intramolecular proton transfer (ESIPT). Laser flash photolysis (LFP) results showed that, only for 2,4-DHA, a phototautomer could be detected at k = 400 nm. Their photochemical stability in solution at different wavelengths and conditions was analyzed by UV–Vis and 1 H nuclear magnetic resonance spectroscopy (1 H-NMR), together with thin layer chromatography and ultraviolet laser desorption/ionization mass spectrometry (UV-LDI-MS). Only 3,5-DHA showed decomposition when irradiated, probably because phototautomerization is not possible. Thermal stability studies of these compounds in solid state were also conducted.
Fil: Tarzi, Olga Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; Argentina
Fil: Di Stéfano, Luciano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; Argentina
Fil: Argüello, Juan Elias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Córdoba. Instituto de Investigaciones en Físicoquímica de Córdoba; Argentina
Fil: Oksdath Mansilla, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Córdoba. Instituto de Investigaciones en Físicoquímica de Córdoba; Argentina
Fil: Erra Balsells, Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono; Argentina
description 2,4-, 2,5-, 2,6- and 3,5-dihydroxyacetophenone (DHA) used as matrices in matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) were studied by steady-state and transient absorption spectroscopy, together with DFT calculations at the B3LYP level of theory. All compounds have low fluorescence quantum yields, possibly due to an efficient excited-state intramolecular proton transfer (ESIPT). Laser flash photolysis (LFP) results showed that, only for 2,4-DHA, a phototautomer could be detected at k = 400 nm. Their photochemical stability in solution at different wavelengths and conditions was analyzed by UV–Vis and 1 H nuclear magnetic resonance spectroscopy (1 H-NMR), together with thin layer chromatography and ultraviolet laser desorption/ionization mass spectrometry (UV-LDI-MS). Only 3,5-DHA showed decomposition when irradiated, probably because phototautomerization is not possible. Thermal stability studies of these compounds in solid state were also conducted.
publishDate 2013
dc.date.none.fl_str_mv 2013-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/2103
Tarzi, Olga Inés; Di Stéfano, Luciano; Argüello, Juan Elias; Oksdath Mansilla, Gabriela; Erra Balsells, Rosa; Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices; Wiley; Photochemistry and Photobiology; 89; 6; 11-2013; 1368-1374
0031-8655
url http://hdl.handle.net/11336/2103
identifier_str_mv Tarzi, Olga Inés; Di Stéfano, Luciano; Argüello, Juan Elias; Oksdath Mansilla, Gabriela; Erra Balsells, Rosa; Photochemical and Thermal 1 Stability of some Dihydroxyacetophenones used as UV-MALDI-MS Matrices; Wiley; Photochemistry and Photobiology; 89; 6; 11-2013; 1368-1374
0031-8655
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/php.12130
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/php.12130/abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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