Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overl...

Autores
Pagani, Ariana Paula; Ibañez, Gabriela Alejandra
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A new methodology involving four-way multivariate calibration with a balanced number of data points in all modes is presented. The method is based on fluorescence excitation-emission matrices modulated by a double pH gradient obtained in a flow injection system. This data array was employed for the quantitation of ciprofloxacin, ofloxacin and norfloxacin in unprocessed urine samples. Due to the presence of potential interfering compounds with overlapping profiles in the analyzed samples, it is required to achieve the second-order advantage. The four-way arrays obtained were processed by parallel factor analysis (PARAFAC), attaining satisfactory results with relative errors of prediction (REP%) between 3% and 7.5% in the analyzed samples for all analytes. The average limit of detection (mg L− 1) was 0.035 for norfloxacin and ofloxacin and 0.028 for ciprofloxacin.
Fil: Pagani, Ariana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
Fil: Ibañez, Gabriela Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
Materia
Excitation-Emission Fluorescence Matrices
Fluoroquinolones
Parafac
Ph-Gradient
Third-Order Multivariate Analysis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/63890
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlappingPagani, Ariana PaulaIbañez, Gabriela AlejandraExcitation-Emission Fluorescence MatricesFluoroquinolonesParafacPh-GradientThird-Order Multivariate Analysishttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A new methodology involving four-way multivariate calibration with a balanced number of data points in all modes is presented. The method is based on fluorescence excitation-emission matrices modulated by a double pH gradient obtained in a flow injection system. This data array was employed for the quantitation of ciprofloxacin, ofloxacin and norfloxacin in unprocessed urine samples. Due to the presence of potential interfering compounds with overlapping profiles in the analyzed samples, it is required to achieve the second-order advantage. The four-way arrays obtained were processed by parallel factor analysis (PARAFAC), attaining satisfactory results with relative errors of prediction (REP%) between 3% and 7.5% in the analyzed samples for all analytes. The average limit of detection (mg L− 1) was 0.035 for norfloxacin and ofloxacin and 0.028 for ciprofloxacin.Fil: Pagani, Ariana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaFil: Ibañez, Gabriela Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaElsevier Science2017-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/63890Pagani, Ariana Paula; Ibañez, Gabriela Alejandra; Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping; Elsevier Science; Microchemical Journal; 132; 5-2017; 211-2180026-265XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.microc.2017.01.028info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0026265X1630371Xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:37:04Zoai:ri.conicet.gov.ar:11336/63890instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:37:04.705CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping
title Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping
spellingShingle Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping
Pagani, Ariana Paula
Excitation-Emission Fluorescence Matrices
Fluoroquinolones
Parafac
Ph-Gradient
Third-Order Multivariate Analysis
title_short Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping
title_full Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping
title_fullStr Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping
title_full_unstemmed Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping
title_sort Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping
dc.creator.none.fl_str_mv Pagani, Ariana Paula
Ibañez, Gabriela Alejandra
author Pagani, Ariana Paula
author_facet Pagani, Ariana Paula
Ibañez, Gabriela Alejandra
author_role author
author2 Ibañez, Gabriela Alejandra
author2_role author
dc.subject.none.fl_str_mv Excitation-Emission Fluorescence Matrices
Fluoroquinolones
Parafac
Ph-Gradient
Third-Order Multivariate Analysis
topic Excitation-Emission Fluorescence Matrices
Fluoroquinolones
Parafac
Ph-Gradient
Third-Order Multivariate Analysis
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A new methodology involving four-way multivariate calibration with a balanced number of data points in all modes is presented. The method is based on fluorescence excitation-emission matrices modulated by a double pH gradient obtained in a flow injection system. This data array was employed for the quantitation of ciprofloxacin, ofloxacin and norfloxacin in unprocessed urine samples. Due to the presence of potential interfering compounds with overlapping profiles in the analyzed samples, it is required to achieve the second-order advantage. The four-way arrays obtained were processed by parallel factor analysis (PARAFAC), attaining satisfactory results with relative errors of prediction (REP%) between 3% and 7.5% in the analyzed samples for all analytes. The average limit of detection (mg L− 1) was 0.035 for norfloxacin and ofloxacin and 0.028 for ciprofloxacin.
Fil: Pagani, Ariana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
Fil: Ibañez, Gabriela Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
description A new methodology involving four-way multivariate calibration with a balanced number of data points in all modes is presented. The method is based on fluorescence excitation-emission matrices modulated by a double pH gradient obtained in a flow injection system. This data array was employed for the quantitation of ciprofloxacin, ofloxacin and norfloxacin in unprocessed urine samples. Due to the presence of potential interfering compounds with overlapping profiles in the analyzed samples, it is required to achieve the second-order advantage. The four-way arrays obtained were processed by parallel factor analysis (PARAFAC), attaining satisfactory results with relative errors of prediction (REP%) between 3% and 7.5% in the analyzed samples for all analytes. The average limit of detection (mg L− 1) was 0.035 for norfloxacin and ofloxacin and 0.028 for ciprofloxacin.
publishDate 2017
dc.date.none.fl_str_mv 2017-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/63890
Pagani, Ariana Paula; Ibañez, Gabriela Alejandra; Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping; Elsevier Science; Microchemical Journal; 132; 5-2017; 211-218
0026-265X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/63890
identifier_str_mv Pagani, Ariana Paula; Ibañez, Gabriela Alejandra; Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices. Analysis of fluoroquinolones in the presence of significant spectral overlapping; Elsevier Science; Microchemical Journal; 132; 5-2017; 211-218
0026-265X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microc.2017.01.028
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0026265X1630371X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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