Ether-linked lipids of rat developing and adult epididymis

Autores
Luquez, Jessica Mariela; Santiago Valtierra, Florencia Ximena; Oresti, Gerardo Martin; Aveldaño, Marta Isabel; Furland, Natalia Edith
Año de publicación
2016
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
In mammalian tissues, glycerophospholipids (GPL) and tri-glycerides (TG) occur in three sublcasses, depending on wheth-er the chain at the sn-1 position of the glycerol backbone is a fatty acid, a fatty alcohol, or a fatty aldehyde. This study fo-cused on the ether-linked (EL) subclasses of GPL and TG, fol-lowing their changes during postnatal development in rat epidi-dymis and, in the adult, their distribution among epididymal caput, corpus and cauda regions. At postnatal day 30, in a still scarcely differentiated epithelium lacking spermatozoa, the epididymis already contained plasmanyl- and plasmenyl-ethanolamine (Pls-Et) with 22:4n-9 (DTA), the DTA-containing plasmenyl-choline (Pls-Cho) increasing with development and the presence of sperm. In the adult tissue, the DTAPls-Et con-centration per mg protein was highest in the corpus and higher than that of DTA-Pls-Cho in the three epididymal regions, sug-gesting a precursor-product relationship. The latter subclass is in turn the one to increase the most in rat spermatozoa as they mature. The epididymal EL-TG were even richer in DTA than the GPL, the 1-alkyl- predominating over the 1-alk-enyl- sub-class at all ages, their concentration being highest in the corpus. These results correlated well with the expression (mRNA) of a key peroxisomal enzyme involved in the biosyn-thesis of these lipids, alkylglycerone phosphate synthase.
Fil: Luquez, Jessica Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Santiago Valtierra, Florencia Ximena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Oresti, Gerardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Aveldaño, Marta Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Furland, Natalia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
52th Annual Meeting Argentine Society for Biochemistry and Molecular Biology; LII Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Córdoba
Argentina
Sociedad Argentina de Investigacion en Bioquimica y Biologia Molecular
Materia
LÍPIDOS CON UNIÓN ÉTER
EPIDÍDIMO
DESARROLLO POSTNATAL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/233187
Acceder
id CONICETDig_35f575dcac30944b5a38b28ac114337f
oai_identifier_str oai:ri.conicet.gov.ar:11336/233187
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Ether-linked lipids of rat developing and adult epididymisLuquez, Jessica MarielaSantiago Valtierra, Florencia XimenaOresti, Gerardo MartinAveldaño, Marta IsabelFurland, Natalia EdithLÍPIDOS CON UNIÓN ÉTEREPIDÍDIMODESARROLLO POSTNATALhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1In mammalian tissues, glycerophospholipids (GPL) and tri-glycerides (TG) occur in three sublcasses, depending on wheth-er the chain at the sn-1 position of the glycerol backbone is a fatty acid, a fatty alcohol, or a fatty aldehyde. This study fo-cused on the ether-linked (EL) subclasses of GPL and TG, fol-lowing their changes during postnatal development in rat epidi-dymis and, in the adult, their distribution among epididymal caput, corpus and cauda regions. At postnatal day 30, in a still scarcely differentiated epithelium lacking spermatozoa, the epididymis already contained plasmanyl- and plasmenyl-ethanolamine (Pls-Et) with 22:4n-9 (DTA), the DTA-containing plasmenyl-choline (Pls-Cho) increasing with development and the presence of sperm. In the adult tissue, the DTAPls-Et con-centration per mg protein was highest in the corpus and higher than that of DTA-Pls-Cho in the three epididymal regions, sug-gesting a precursor-product relationship. The latter subclass is in turn the one to increase the most in rat spermatozoa as they mature. The epididymal EL-TG were even richer in DTA than the GPL, the 1-alkyl- predominating over the 1-alk-enyl- sub-class at all ages, their concentration being highest in the corpus. These results correlated well with the expression (mRNA) of a key peroxisomal enzyme involved in the biosyn-thesis of these lipids, alkylglycerone phosphate synthase.Fil: Luquez, Jessica Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaFil: Santiago Valtierra, Florencia Ximena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaFil: Oresti, Gerardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaFil: Aveldaño, Marta Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaFil: Furland, Natalia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina52th Annual Meeting Argentine Society for Biochemistry and Molecular Biology; LII Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología MolecularCórdobaArgentinaSociedad Argentina de Investigacion en Bioquimica y Biologia MolecularTech Science Press2016info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoJournalhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/233187Ether-linked lipids of rat developing and adult epididymis; 52th Annual Meeting Argentine Society for Biochemistry and Molecular Biology; LII Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular; Córdoba; Argentina; 2016; 105-1050327-95451667-5746CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.techscience.com/biocell/v40nSuppl.S/34023/pdfNacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:25:02Zoai:ri.conicet.gov.ar:11336/233187instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:25:02.549CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Ether-linked lipids of rat developing and adult epididymis
title Ether-linked lipids of rat developing and adult epididymis
spellingShingle Ether-linked lipids of rat developing and adult epididymis
Luquez, Jessica Mariela
LÍPIDOS CON UNIÓN ÉTER
EPIDÍDIMO
DESARROLLO POSTNATAL
title_short Ether-linked lipids of rat developing and adult epididymis
title_full Ether-linked lipids of rat developing and adult epididymis
title_fullStr Ether-linked lipids of rat developing and adult epididymis
title_full_unstemmed Ether-linked lipids of rat developing and adult epididymis
title_sort Ether-linked lipids of rat developing and adult epididymis
dc.creator.none.fl_str_mv Luquez, Jessica Mariela
Santiago Valtierra, Florencia Ximena
Oresti, Gerardo Martin
Aveldaño, Marta Isabel
Furland, Natalia Edith
author Luquez, Jessica Mariela
author_facet Luquez, Jessica Mariela
Santiago Valtierra, Florencia Ximena
Oresti, Gerardo Martin
Aveldaño, Marta Isabel
Furland, Natalia Edith
author_role author
author2 Santiago Valtierra, Florencia Ximena
Oresti, Gerardo Martin
Aveldaño, Marta Isabel
Furland, Natalia Edith
author2_role author
author
author
author
dc.subject.none.fl_str_mv LÍPIDOS CON UNIÓN ÉTER
EPIDÍDIMO
DESARROLLO POSTNATAL
topic LÍPIDOS CON UNIÓN ÉTER
EPIDÍDIMO
DESARROLLO POSTNATAL
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In mammalian tissues, glycerophospholipids (GPL) and tri-glycerides (TG) occur in three sublcasses, depending on wheth-er the chain at the sn-1 position of the glycerol backbone is a fatty acid, a fatty alcohol, or a fatty aldehyde. This study fo-cused on the ether-linked (EL) subclasses of GPL and TG, fol-lowing their changes during postnatal development in rat epidi-dymis and, in the adult, their distribution among epididymal caput, corpus and cauda regions. At postnatal day 30, in a still scarcely differentiated epithelium lacking spermatozoa, the epididymis already contained plasmanyl- and plasmenyl-ethanolamine (Pls-Et) with 22:4n-9 (DTA), the DTA-containing plasmenyl-choline (Pls-Cho) increasing with development and the presence of sperm. In the adult tissue, the DTAPls-Et con-centration per mg protein was highest in the corpus and higher than that of DTA-Pls-Cho in the three epididymal regions, sug-gesting a precursor-product relationship. The latter subclass is in turn the one to increase the most in rat spermatozoa as they mature. The epididymal EL-TG were even richer in DTA than the GPL, the 1-alkyl- predominating over the 1-alk-enyl- sub-class at all ages, their concentration being highest in the corpus. These results correlated well with the expression (mRNA) of a key peroxisomal enzyme involved in the biosyn-thesis of these lipids, alkylglycerone phosphate synthase.
Fil: Luquez, Jessica Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Santiago Valtierra, Florencia Ximena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Oresti, Gerardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Aveldaño, Marta Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Furland, Natalia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
52th Annual Meeting Argentine Society for Biochemistry and Molecular Biology; LII Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Córdoba
Argentina
Sociedad Argentina de Investigacion en Bioquimica y Biologia Molecular
description In mammalian tissues, glycerophospholipids (GPL) and tri-glycerides (TG) occur in three sublcasses, depending on wheth-er the chain at the sn-1 position of the glycerol backbone is a fatty acid, a fatty alcohol, or a fatty aldehyde. This study fo-cused on the ether-linked (EL) subclasses of GPL and TG, fol-lowing their changes during postnatal development in rat epidi-dymis and, in the adult, their distribution among epididymal caput, corpus and cauda regions. At postnatal day 30, in a still scarcely differentiated epithelium lacking spermatozoa, the epididymis already contained plasmanyl- and plasmenyl-ethanolamine (Pls-Et) with 22:4n-9 (DTA), the DTA-containing plasmenyl-choline (Pls-Cho) increasing with development and the presence of sperm. In the adult tissue, the DTAPls-Et con-centration per mg protein was highest in the corpus and higher than that of DTA-Pls-Cho in the three epididymal regions, sug-gesting a precursor-product relationship. The latter subclass is in turn the one to increase the most in rat spermatozoa as they mature. The epididymal EL-TG were even richer in DTA than the GPL, the 1-alkyl- predominating over the 1-alk-enyl- sub-class at all ages, their concentration being highest in the corpus. These results correlated well with the expression (mRNA) of a key peroxisomal enzyme involved in the biosyn-thesis of these lipids, alkylglycerone phosphate synthase.
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Congreso
Journal
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/233187
Ether-linked lipids of rat developing and adult epididymis; 52th Annual Meeting Argentine Society for Biochemistry and Molecular Biology; LII Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular; Córdoba; Argentina; 2016; 105-105
0327-9545
1667-5746
CONICET Digital
CONICET
url http://hdl.handle.net/11336/233187
identifier_str_mv Ether-linked lipids of rat developing and adult epididymis; 52th Annual Meeting Argentine Society for Biochemistry and Molecular Biology; LII Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular; Córdoba; Argentina; 2016; 105-105
0327-9545
1667-5746
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.techscience.com/biocell/v40nSuppl.S/34023/pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
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dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.coverage.none.fl_str_mv Nacional
dc.publisher.none.fl_str_mv Tech Science Press
publisher.none.fl_str_mv Tech Science Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
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repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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