Ether-linked triglycerides of rat epididymis

Autores
Luquez, Jessica Mariela; Oresti, Gerardo Martin; Aveldaño, Marta Isabel; Furland, Natalia Edith
Año de publicación
2011
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Long-chain n-9 polyunsaturated fatty acids (PUFA), particularly 22:4n-9, are normal components of the plasmenylcholines of rat epididymal spermatozoa. Since these uncommon PUFA are absent from lipids of testicular cells, their accretion is expected to occur during the passage of the gametes through the epididymis. In this work we focused on the neutral lipids that are present in the epididymal caput, corpus, and cauda regions. In addition to cholesteryl esters, the three areas contained ether-linked triglycerides (1-O-alkyl-, and 1-alk-1´enyl- diacylglycerols, ADG). Interestingly, the latter were characterized by high proportions of n9 PUFA. The amounts of these ADG gradually increased during development: they were detected in rat epididymis on day 14 after birth (P14), their amounts increased markedly at P49, in association with the complete differentiation of all epididymal cells, while reaching maximum levels at P55, the time at which the first spermatozoa appeared in the epididymal lumen. In adult rats, the smallest but metabolically most active portion of the epididymis, the corpus, had relatively more 22:4n-9-rich ADG than the other two regions. Our data suggest that epididymal ADG may be involved as lipid intermediates during the active membrane remodeling that spermatozoa are known to undergo during their extra-testicular maturation.
Fil: Luquez, Jessica Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Oresti, Gerardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Aveldaño, Marta Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Furland, Natalia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
XLVII Reunión Nacional de la Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Potrero de los Funes
Argentina
Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Materia
TRIGLYCERIDES
RAT EPIDIDYMIS
N-9/N-6 FATTY ACIDS
PLASMALOGENS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/242440
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/242440
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Ether-linked triglycerides of rat epididymisLuquez, Jessica MarielaOresti, Gerardo MartinAveldaño, Marta IsabelFurland, Natalia EdithTRIGLYCERIDESRAT EPIDIDYMISN-9/N-6 FATTY ACIDSPLASMALOGENShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Long-chain n-9 polyunsaturated fatty acids (PUFA), particularly 22:4n-9, are normal components of the plasmenylcholines of rat epididymal spermatozoa. Since these uncommon PUFA are absent from lipids of testicular cells, their accretion is expected to occur during the passage of the gametes through the epididymis. In this work we focused on the neutral lipids that are present in the epididymal caput, corpus, and cauda regions. In addition to cholesteryl esters, the three areas contained ether-linked triglycerides (1-O-alkyl-, and 1-alk-1´enyl- diacylglycerols, ADG). Interestingly, the latter were characterized by high proportions of n9 PUFA. The amounts of these ADG gradually increased during development: they were detected in rat epididymis on day 14 after birth (P14), their amounts increased markedly at P49, in association with the complete differentiation of all epididymal cells, while reaching maximum levels at P55, the time at which the first spermatozoa appeared in the epididymal lumen. In adult rats, the smallest but metabolically most active portion of the epididymis, the corpus, had relatively more 22:4n-9-rich ADG than the other two regions. Our data suggest that epididymal ADG may be involved as lipid intermediates during the active membrane remodeling that spermatozoa are known to undergo during their extra-testicular maturation.Fil: Luquez, Jessica Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaFil: Oresti, Gerardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaFil: Aveldaño, Marta Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaFil: Furland, Natalia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaXLVII Reunión Nacional de la Sociedad Argentina de Investigación en Bioquímica y Biología MolecularPotrero de los FunesArgentinaSociedad Argentina de Investigación en Bioquímica y Biología MolecularBiocell2011info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoJournalhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/242440Ether-linked triglycerides of rat epididymis; XLVII Reunión Nacional de la Sociedad Argentina de Investigación en Bioquímica y Biología Molecular; Potrero de los Funes; Argentina; 2011; 100-1000327-95451667-5746CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://newsite.saib.org.ar/publicaciones/Nacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:49:01Zoai:ri.conicet.gov.ar:11336/242440instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:49:01.711CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Ether-linked triglycerides of rat epididymis
title Ether-linked triglycerides of rat epididymis
spellingShingle Ether-linked triglycerides of rat epididymis
Luquez, Jessica Mariela
TRIGLYCERIDES
RAT EPIDIDYMIS
N-9/N-6 FATTY ACIDS
PLASMALOGENS
title_short Ether-linked triglycerides of rat epididymis
title_full Ether-linked triglycerides of rat epididymis
title_fullStr Ether-linked triglycerides of rat epididymis
title_full_unstemmed Ether-linked triglycerides of rat epididymis
title_sort Ether-linked triglycerides of rat epididymis
dc.creator.none.fl_str_mv Luquez, Jessica Mariela
Oresti, Gerardo Martin
Aveldaño, Marta Isabel
Furland, Natalia Edith
author Luquez, Jessica Mariela
author_facet Luquez, Jessica Mariela
Oresti, Gerardo Martin
Aveldaño, Marta Isabel
Furland, Natalia Edith
author_role author
author2 Oresti, Gerardo Martin
Aveldaño, Marta Isabel
Furland, Natalia Edith
author2_role author
author
author
dc.subject.none.fl_str_mv TRIGLYCERIDES
RAT EPIDIDYMIS
N-9/N-6 FATTY ACIDS
PLASMALOGENS
topic TRIGLYCERIDES
RAT EPIDIDYMIS
N-9/N-6 FATTY ACIDS
PLASMALOGENS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Long-chain n-9 polyunsaturated fatty acids (PUFA), particularly 22:4n-9, are normal components of the plasmenylcholines of rat epididymal spermatozoa. Since these uncommon PUFA are absent from lipids of testicular cells, their accretion is expected to occur during the passage of the gametes through the epididymis. In this work we focused on the neutral lipids that are present in the epididymal caput, corpus, and cauda regions. In addition to cholesteryl esters, the three areas contained ether-linked triglycerides (1-O-alkyl-, and 1-alk-1´enyl- diacylglycerols, ADG). Interestingly, the latter were characterized by high proportions of n9 PUFA. The amounts of these ADG gradually increased during development: they were detected in rat epididymis on day 14 after birth (P14), their amounts increased markedly at P49, in association with the complete differentiation of all epididymal cells, while reaching maximum levels at P55, the time at which the first spermatozoa appeared in the epididymal lumen. In adult rats, the smallest but metabolically most active portion of the epididymis, the corpus, had relatively more 22:4n-9-rich ADG than the other two regions. Our data suggest that epididymal ADG may be involved as lipid intermediates during the active membrane remodeling that spermatozoa are known to undergo during their extra-testicular maturation.
Fil: Luquez, Jessica Mariela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Oresti, Gerardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Aveldaño, Marta Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
Fil: Furland, Natalia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina
XLVII Reunión Nacional de la Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Potrero de los Funes
Argentina
Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
description Long-chain n-9 polyunsaturated fatty acids (PUFA), particularly 22:4n-9, are normal components of the plasmenylcholines of rat epididymal spermatozoa. Since these uncommon PUFA are absent from lipids of testicular cells, their accretion is expected to occur during the passage of the gametes through the epididymis. In this work we focused on the neutral lipids that are present in the epididymal caput, corpus, and cauda regions. In addition to cholesteryl esters, the three areas contained ether-linked triglycerides (1-O-alkyl-, and 1-alk-1´enyl- diacylglycerols, ADG). Interestingly, the latter were characterized by high proportions of n9 PUFA. The amounts of these ADG gradually increased during development: they were detected in rat epididymis on day 14 after birth (P14), their amounts increased markedly at P49, in association with the complete differentiation of all epididymal cells, while reaching maximum levels at P55, the time at which the first spermatozoa appeared in the epididymal lumen. In adult rats, the smallest but metabolically most active portion of the epididymis, the corpus, had relatively more 22:4n-9-rich ADG than the other two regions. Our data suggest that epididymal ADG may be involved as lipid intermediates during the active membrane remodeling that spermatozoa are known to undergo during their extra-testicular maturation.
publishDate 2011
dc.date.none.fl_str_mv 2011
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Congreso
Journal
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/242440
Ether-linked triglycerides of rat epididymis; XLVII Reunión Nacional de la Sociedad Argentina de Investigación en Bioquímica y Biología Molecular; Potrero de los Funes; Argentina; 2011; 100-100
0327-9545
1667-5746
CONICET Digital
CONICET
url http://hdl.handle.net/11336/242440
identifier_str_mv Ether-linked triglycerides of rat epididymis; XLVII Reunión Nacional de la Sociedad Argentina de Investigación en Bioquímica y Biología Molecular; Potrero de los Funes; Argentina; 2011; 100-100
0327-9545
1667-5746
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://newsite.saib.org.ar/publicaciones/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.coverage.none.fl_str_mv Nacional
dc.publisher.none.fl_str_mv Biocell
publisher.none.fl_str_mv Biocell
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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