High-affinity binding of T3 to Epididymis Nuclei

Autores
Del Rio, A. G.; Blanco, A. M.; Pignataro, Omar Pedro; Niepomniszcze, H.; Juvenal, Guillermo Juan; Pisarev, Mario Alberto
Año de publicación
2000
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Thyroid hormones play an important role in epididymal function. Hypothyroid animals experience a significant decrease in the number and forward motility of sperm and a remarkable impairment of epididymal morphology. However, it is yet unknown if such activity is due to direct actions of iodothyronines on the target epididymis. The eventual identification of T3 receptors in the nucleous of epididymal cells becomes relevant. For this reason, the authors searched for specific high-affinity binding of T3 to these nuclei. Twenty prepuberal male Wistar rats were used. The testes and epididymis were approached as one unit through a scrotal incision. The fat-free epididymides were subjected to standard techniques to prepare the nuclei for incubations with 125I-T3
Fil: Del Rio, A. G.. Universidad de Buenos Aires; Argentina
Fil: Blanco, A. M.. Universidad de Buenos Aires; Argentina
Fil: Pignataro, Omar Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Niepomniszcze, H.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Fil: Juvenal, Guillermo Juan. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Hormonas Tiroideas
Epidídimo
Receptores Hormonas Tiroideas
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/72055
Acceder
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network_name_str CONICET Digital (CONICET)
spelling High-affinity binding of T3 to Epididymis NucleiDel Rio, A. G.Blanco, A. M.Pignataro, Omar PedroNiepomniszcze, H.Juvenal, Guillermo JuanPisarev, Mario AlbertoHormonas TiroideasEpidídimoReceptores Hormonas Tiroideashttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Thyroid hormones play an important role in epididymal function. Hypothyroid animals experience a significant decrease in the number and forward motility of sperm and a remarkable impairment of epididymal morphology. However, it is yet unknown if such activity is due to direct actions of iodothyronines on the target epididymis. The eventual identification of T3 receptors in the nucleous of epididymal cells becomes relevant. For this reason, the authors searched for specific high-affinity binding of T3 to these nuclei. Twenty prepuberal male Wistar rats were used. The testes and epididymis were approached as one unit through a scrotal incision. The fat-free epididymides were subjected to standard techniques to prepare the nuclei for incubations with 125I-T3Fil: Del Rio, A. G.. Universidad de Buenos Aires; ArgentinaFil: Blanco, A. M.. Universidad de Buenos Aires; ArgentinaFil: Pignataro, Omar Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Niepomniszcze, H.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Juvenal, Guillermo Juan. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaTaylor & Francis2000-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/mswordapplication/pdfhttp://hdl.handle.net/11336/72055Del Rio, A. G.; Blanco, A. M.; Pignataro, Omar Pedro; Niepomniszcze, H.; Juvenal, Guillermo Juan; et al.; High-affinity binding of T3 to Epididymis Nuclei; Taylor & Francis; Archives Of Andrology; 44; 3; 7-2000; 187-1910148-5016CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1080/014850100262155info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.1080/014850100262155info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:23:09Zoai:ri.conicet.gov.ar:11336/72055instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:23:09.392CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv High-affinity binding of T3 to Epididymis Nuclei
title High-affinity binding of T3 to Epididymis Nuclei
spellingShingle High-affinity binding of T3 to Epididymis Nuclei
Del Rio, A. G.
Hormonas Tiroideas
Epidídimo
Receptores Hormonas Tiroideas
title_short High-affinity binding of T3 to Epididymis Nuclei
title_full High-affinity binding of T3 to Epididymis Nuclei
title_fullStr High-affinity binding of T3 to Epididymis Nuclei
title_full_unstemmed High-affinity binding of T3 to Epididymis Nuclei
title_sort High-affinity binding of T3 to Epididymis Nuclei
dc.creator.none.fl_str_mv Del Rio, A. G.
Blanco, A. M.
Pignataro, Omar Pedro
Niepomniszcze, H.
Juvenal, Guillermo Juan
Pisarev, Mario Alberto
author Del Rio, A. G.
author_facet Del Rio, A. G.
Blanco, A. M.
Pignataro, Omar Pedro
Niepomniszcze, H.
Juvenal, Guillermo Juan
Pisarev, Mario Alberto
author_role author
author2 Blanco, A. M.
Pignataro, Omar Pedro
Niepomniszcze, H.
Juvenal, Guillermo Juan
Pisarev, Mario Alberto
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Hormonas Tiroideas
Epidídimo
Receptores Hormonas Tiroideas
topic Hormonas Tiroideas
Epidídimo
Receptores Hormonas Tiroideas
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Thyroid hormones play an important role in epididymal function. Hypothyroid animals experience a significant decrease in the number and forward motility of sperm and a remarkable impairment of epididymal morphology. However, it is yet unknown if such activity is due to direct actions of iodothyronines on the target epididymis. The eventual identification of T3 receptors in the nucleous of epididymal cells becomes relevant. For this reason, the authors searched for specific high-affinity binding of T3 to these nuclei. Twenty prepuberal male Wistar rats were used. The testes and epididymis were approached as one unit through a scrotal incision. The fat-free epididymides were subjected to standard techniques to prepare the nuclei for incubations with 125I-T3
Fil: Del Rio, A. G.. Universidad de Buenos Aires; Argentina
Fil: Blanco, A. M.. Universidad de Buenos Aires; Argentina
Fil: Pignataro, Omar Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Niepomniszcze, H.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Fil: Juvenal, Guillermo Juan. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pisarev, Mario Alberto. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Thyroid hormones play an important role in epididymal function. Hypothyroid animals experience a significant decrease in the number and forward motility of sperm and a remarkable impairment of epididymal morphology. However, it is yet unknown if such activity is due to direct actions of iodothyronines on the target epididymis. The eventual identification of T3 receptors in the nucleous of epididymal cells becomes relevant. For this reason, the authors searched for specific high-affinity binding of T3 to these nuclei. Twenty prepuberal male Wistar rats were used. The testes and epididymis were approached as one unit through a scrotal incision. The fat-free epididymides were subjected to standard techniques to prepare the nuclei for incubations with 125I-T3
publishDate 2000
dc.date.none.fl_str_mv 2000-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/72055
Del Rio, A. G.; Blanco, A. M.; Pignataro, Omar Pedro; Niepomniszcze, H.; Juvenal, Guillermo Juan; et al.; High-affinity binding of T3 to Epididymis Nuclei; Taylor & Francis; Archives Of Andrology; 44; 3; 7-2000; 187-191
0148-5016
CONICET Digital
CONICET
url http://hdl.handle.net/11336/72055
identifier_str_mv Del Rio, A. G.; Blanco, A. M.; Pignataro, Omar Pedro; Niepomniszcze, H.; Juvenal, Guillermo Juan; et al.; High-affinity binding of T3 to Epididymis Nuclei; Taylor & Francis; Archives Of Andrology; 44; 3; 7-2000; 187-191
0148-5016
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1080/014850100262155
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.1080/014850100262155
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/msword
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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