Antifungal Activity of extracts from two Ouratea species on Candida albicans

Autores
de Araújo, Marcelo Francisco; Catunda, Francisco Eduardo Aragão; Alvarez, María Gabriela; Durantini, Edgardo Néstor; Carvalho, Mário Geraldo de
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Plants are invaluable sources of pharmaceutical products and Brazil, in particular, has yielded an incredible array of plant and animal products that have drawn the attention of ethnopharmacologists from around the world. Ouratea is a genus of tropical plants within the Ochnaceae. Ouratea is widespread throughtout the tropics, with species in Costa Rica, Brazil, Jamaica, and Kenya. The search for compounds with antimicrobial activity is urgent and indispensable for the treatment of infectious diseases caused by microorganisms resistant to traditional antimicrobial drugs. A screening was conducted with organic extracts from two species, from roots and leaves of Ouratea hexasperma var. planchonii Engl. and leaves and branches of Ouratea parviflora Engl., to identify plant extracts with antifungal properties against Candida albicans. Initially, minimal inhibitory concentrations (MICs) were determined in C. albicans cellular suspension in Sabouraud medium, in a range of 0.060-3.0 mg/ml. Fractions OHRMWE (Ethyl acetate fraction) and OHLMWB (Buthanol fraction) obtained by solvents partition of methanol:water extract from Ouratea hexasperma with ethyl acetate from the roots and n-butanol from the leaves, respectively, showed a higher antifungal activity. The antifungal activity of these extracts was also compared in growth delay of C. albicans cultures.
Fil: de Araújo, Marcelo Francisco. Universidade Federal Rural do Rio de Janeiro; Brasil
Fil: Catunda, Francisco Eduardo Aragão. Universidade Federal Rural do Rio de Janeiro; Brasil
Fil: Alvarez, María Gabriela. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Durantini, Edgardo Néstor. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Carvalho, Mário Geraldo de. Universidade Federal Rural do Rio de Janeiro; Brasil
Materia
ANTIFUNGAL
CANDIDA ALBICANS
YEAST
EXTRACT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/23392
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Antifungal Activity of extracts from two Ouratea species on Candida albicansde Araújo, Marcelo FranciscoCatunda, Francisco Eduardo AragãoAlvarez, María GabrielaDurantini, Edgardo NéstorCarvalho, Mário Geraldo deANTIFUNGALCANDIDA ALBICANSYEASTEXTRACThttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Plants are invaluable sources of pharmaceutical products and Brazil, in particular, has yielded an incredible array of plant and animal products that have drawn the attention of ethnopharmacologists from around the world. Ouratea is a genus of tropical plants within the Ochnaceae. Ouratea is widespread throughtout the tropics, with species in Costa Rica, Brazil, Jamaica, and Kenya. The search for compounds with antimicrobial activity is urgent and indispensable for the treatment of infectious diseases caused by microorganisms resistant to traditional antimicrobial drugs. A screening was conducted with organic extracts from two species, from roots and leaves of Ouratea hexasperma var. planchonii Engl. and leaves and branches of Ouratea parviflora Engl., to identify plant extracts with antifungal properties against Candida albicans. Initially, minimal inhibitory concentrations (MICs) were determined in C. albicans cellular suspension in Sabouraud medium, in a range of 0.060-3.0 mg/ml. Fractions OHRMWE (Ethyl acetate fraction) and OHLMWB (Buthanol fraction) obtained by solvents partition of methanol:water extract from Ouratea hexasperma with ethyl acetate from the roots and n-butanol from the leaves, respectively, showed a higher antifungal activity. The antifungal activity of these extracts was also compared in growth delay of C. albicans cultures.Fil: de Araújo, Marcelo Francisco. Universidade Federal Rural do Rio de Janeiro; BrasilFil: Catunda, Francisco Eduardo Aragão. Universidade Federal Rural do Rio de Janeiro; BrasilFil: Alvarez, María Gabriela. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Durantini, Edgardo Néstor. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Carvalho, Mário Geraldo de. Universidade Federal Rural do Rio de Janeiro; BrasilWorld association of Medical Editors2013-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/23392de Araújo, Marcelo Francisco; Catunda, Francisco Eduardo Aragão; Alvarez, María Gabriela; Durantini, Edgardo Néstor; Carvalho, Mário Geraldo de; Antifungal Activity of extracts from two Ouratea species on Candida albicans; World association of Medical Editors; Journal of Applied Pharmaceutical Science; 3; 6; 6-2013; 152-1552231-3354CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.7324/JAPS.2013.3625info:eu-repo/semantics/altIdentifier/url/http://www.japsonline.com/abstract.php?article_id=940info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:26:04Zoai:ri.conicet.gov.ar:11336/23392instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:26:04.347CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antifungal Activity of extracts from two Ouratea species on Candida albicans
title Antifungal Activity of extracts from two Ouratea species on Candida albicans
spellingShingle Antifungal Activity of extracts from two Ouratea species on Candida albicans
de Araújo, Marcelo Francisco
ANTIFUNGAL
CANDIDA ALBICANS
YEAST
EXTRACT
title_short Antifungal Activity of extracts from two Ouratea species on Candida albicans
title_full Antifungal Activity of extracts from two Ouratea species on Candida albicans
title_fullStr Antifungal Activity of extracts from two Ouratea species on Candida albicans
title_full_unstemmed Antifungal Activity of extracts from two Ouratea species on Candida albicans
title_sort Antifungal Activity of extracts from two Ouratea species on Candida albicans
dc.creator.none.fl_str_mv de Araújo, Marcelo Francisco
Catunda, Francisco Eduardo Aragão
Alvarez, María Gabriela
Durantini, Edgardo Néstor
Carvalho, Mário Geraldo de
author de Araújo, Marcelo Francisco
author_facet de Araújo, Marcelo Francisco
Catunda, Francisco Eduardo Aragão
Alvarez, María Gabriela
Durantini, Edgardo Néstor
Carvalho, Mário Geraldo de
author_role author
author2 Catunda, Francisco Eduardo Aragão
Alvarez, María Gabriela
Durantini, Edgardo Néstor
Carvalho, Mário Geraldo de
author2_role author
author
author
author
dc.subject.none.fl_str_mv ANTIFUNGAL
CANDIDA ALBICANS
YEAST
EXTRACT
topic ANTIFUNGAL
CANDIDA ALBICANS
YEAST
EXTRACT
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Plants are invaluable sources of pharmaceutical products and Brazil, in particular, has yielded an incredible array of plant and animal products that have drawn the attention of ethnopharmacologists from around the world. Ouratea is a genus of tropical plants within the Ochnaceae. Ouratea is widespread throughtout the tropics, with species in Costa Rica, Brazil, Jamaica, and Kenya. The search for compounds with antimicrobial activity is urgent and indispensable for the treatment of infectious diseases caused by microorganisms resistant to traditional antimicrobial drugs. A screening was conducted with organic extracts from two species, from roots and leaves of Ouratea hexasperma var. planchonii Engl. and leaves and branches of Ouratea parviflora Engl., to identify plant extracts with antifungal properties against Candida albicans. Initially, minimal inhibitory concentrations (MICs) were determined in C. albicans cellular suspension in Sabouraud medium, in a range of 0.060-3.0 mg/ml. Fractions OHRMWE (Ethyl acetate fraction) and OHLMWB (Buthanol fraction) obtained by solvents partition of methanol:water extract from Ouratea hexasperma with ethyl acetate from the roots and n-butanol from the leaves, respectively, showed a higher antifungal activity. The antifungal activity of these extracts was also compared in growth delay of C. albicans cultures.
Fil: de Araújo, Marcelo Francisco. Universidade Federal Rural do Rio de Janeiro; Brasil
Fil: Catunda, Francisco Eduardo Aragão. Universidade Federal Rural do Rio de Janeiro; Brasil
Fil: Alvarez, María Gabriela. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Durantini, Edgardo Néstor. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Carvalho, Mário Geraldo de. Universidade Federal Rural do Rio de Janeiro; Brasil
description Plants are invaluable sources of pharmaceutical products and Brazil, in particular, has yielded an incredible array of plant and animal products that have drawn the attention of ethnopharmacologists from around the world. Ouratea is a genus of tropical plants within the Ochnaceae. Ouratea is widespread throughtout the tropics, with species in Costa Rica, Brazil, Jamaica, and Kenya. The search for compounds with antimicrobial activity is urgent and indispensable for the treatment of infectious diseases caused by microorganisms resistant to traditional antimicrobial drugs. A screening was conducted with organic extracts from two species, from roots and leaves of Ouratea hexasperma var. planchonii Engl. and leaves and branches of Ouratea parviflora Engl., to identify plant extracts with antifungal properties against Candida albicans. Initially, minimal inhibitory concentrations (MICs) were determined in C. albicans cellular suspension in Sabouraud medium, in a range of 0.060-3.0 mg/ml. Fractions OHRMWE (Ethyl acetate fraction) and OHLMWB (Buthanol fraction) obtained by solvents partition of methanol:water extract from Ouratea hexasperma with ethyl acetate from the roots and n-butanol from the leaves, respectively, showed a higher antifungal activity. The antifungal activity of these extracts was also compared in growth delay of C. albicans cultures.
publishDate 2013
dc.date.none.fl_str_mv 2013-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/23392
de Araújo, Marcelo Francisco; Catunda, Francisco Eduardo Aragão; Alvarez, María Gabriela; Durantini, Edgardo Néstor; Carvalho, Mário Geraldo de; Antifungal Activity of extracts from two Ouratea species on Candida albicans; World association of Medical Editors; Journal of Applied Pharmaceutical Science; 3; 6; 6-2013; 152-155
2231-3354
CONICET Digital
CONICET
url http://hdl.handle.net/11336/23392
identifier_str_mv de Araújo, Marcelo Francisco; Catunda, Francisco Eduardo Aragão; Alvarez, María Gabriela; Durantini, Edgardo Néstor; Carvalho, Mário Geraldo de; Antifungal Activity of extracts from two Ouratea species on Candida albicans; World association of Medical Editors; Journal of Applied Pharmaceutical Science; 3; 6; 6-2013; 152-155
2231-3354
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.7324/JAPS.2013.3625
info:eu-repo/semantics/altIdentifier/url/http://www.japsonline.com/abstract.php?article_id=940
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv World association of Medical Editors
publisher.none.fl_str_mv World association of Medical Editors
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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