Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery

Autores
Andrade, Fernanda; Goycoolea, Francisco; Chiappetta, Diego Andrés; Das Neves, José; Sosnik, Alejandro Dario; Sarmento, Bruno
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Recently, much attention has been given to pulmonary drug delivery by means of nanosized systems to treat both local and systemic diseases. Among the differentmaterials used for the production of nanocarriers, chitosan enjoys high popularity due to its inherent characteristics such as biocompatibility, biodegradability, and mucoadhesion, among others. Through the modification of chitosan chemical structure, either by the addition of new chemical groups or by the functionalization with ligands, it is possible to obtain derivatives with advantageous and specific characteristics for pulmonary administration. In this paper, we discuss the advantages of using chitosan for nanotechnology-based pulmonary delivery of drugs and summarize the most recent and promising modifications performed to the chitosan molecule in order to improve its characteristics.
Fil: Andrade, Fernanda. Universidad de Porto; Portugal
Fil: Goycoolea, Francisco. Westfalische Wilhelms Universitat; Alemania
Fil: Chiappetta, Diego Andrés. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Das Neves, José. Universidad de Porto; Portugal
Fil: Sosnik, Alejandro Dario. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Sarmento, Bruno. Universidad de Porto; Portugal. Instituto Superior de Ciências da Saúde-Norte; Portugal
Materia
CHITOSAN
PULMONARY DRUG DELIVERY
CHITOSAN-GRAFTED COPOLYMERS
NANOPARTICLES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/12914
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/12914
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug DeliveryAndrade, FernandaGoycoolea, FranciscoChiappetta, Diego AndrésDas Neves, JoséSosnik, Alejandro DarioSarmento, BrunoCHITOSANPULMONARY DRUG DELIVERYCHITOSAN-GRAFTED COPOLYMERSNANOPARTICLEShttps://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2https://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2Recently, much attention has been given to pulmonary drug delivery by means of nanosized systems to treat both local and systemic diseases. Among the differentmaterials used for the production of nanocarriers, chitosan enjoys high popularity due to its inherent characteristics such as biocompatibility, biodegradability, and mucoadhesion, among others. Through the modification of chitosan chemical structure, either by the addition of new chemical groups or by the functionalization with ligands, it is possible to obtain derivatives with advantageous and specific characteristics for pulmonary administration. In this paper, we discuss the advantages of using chitosan for nanotechnology-based pulmonary delivery of drugs and summarize the most recent and promising modifications performed to the chitosan molecule in order to improve its characteristics.Fil: Andrade, Fernanda. Universidad de Porto; PortugalFil: Goycoolea, Francisco. Westfalische Wilhelms Universitat; AlemaniaFil: Chiappetta, Diego Andrés. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Das Neves, José. Universidad de Porto; PortugalFil: Sosnik, Alejandro Dario. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Sarmento, Bruno. Universidad de Porto; Portugal. Instituto Superior de Ciências da Saúde-Norte; PortugalHindawi Publishing Corporation2011-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/12914Andrade, Fernanda; Goycoolea, Francisco; Chiappetta, Diego Andrés; Das Neves, José; Sosnik, Alejandro Dario; et al.; Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery; Hindawi Publishing Corporation; International Journal of Carbohydrate Chemistry; 2011; 865704; 10-2011; 1-141687-935Xenginfo:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/ijcc/2011/865704/info:eu-repo/semantics/altIdentifier/doi/10.1155/2011/865704info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:39:27Zoai:ri.conicet.gov.ar:11336/12914instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:39:27.503CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
title Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
spellingShingle Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
Andrade, Fernanda
CHITOSAN
PULMONARY DRUG DELIVERY
CHITOSAN-GRAFTED COPOLYMERS
NANOPARTICLES
title_short Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
title_full Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
title_fullStr Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
title_full_unstemmed Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
title_sort Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
dc.creator.none.fl_str_mv Andrade, Fernanda
Goycoolea, Francisco
Chiappetta, Diego Andrés
Das Neves, José
Sosnik, Alejandro Dario
Sarmento, Bruno
author Andrade, Fernanda
author_facet Andrade, Fernanda
Goycoolea, Francisco
Chiappetta, Diego Andrés
Das Neves, José
Sosnik, Alejandro Dario
Sarmento, Bruno
author_role author
author2 Goycoolea, Francisco
Chiappetta, Diego Andrés
Das Neves, José
Sosnik, Alejandro Dario
Sarmento, Bruno
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv CHITOSAN
PULMONARY DRUG DELIVERY
CHITOSAN-GRAFTED COPOLYMERS
NANOPARTICLES
topic CHITOSAN
PULMONARY DRUG DELIVERY
CHITOSAN-GRAFTED COPOLYMERS
NANOPARTICLES
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Recently, much attention has been given to pulmonary drug delivery by means of nanosized systems to treat both local and systemic diseases. Among the differentmaterials used for the production of nanocarriers, chitosan enjoys high popularity due to its inherent characteristics such as biocompatibility, biodegradability, and mucoadhesion, among others. Through the modification of chitosan chemical structure, either by the addition of new chemical groups or by the functionalization with ligands, it is possible to obtain derivatives with advantageous and specific characteristics for pulmonary administration. In this paper, we discuss the advantages of using chitosan for nanotechnology-based pulmonary delivery of drugs and summarize the most recent and promising modifications performed to the chitosan molecule in order to improve its characteristics.
Fil: Andrade, Fernanda. Universidad de Porto; Portugal
Fil: Goycoolea, Francisco. Westfalische Wilhelms Universitat; Alemania
Fil: Chiappetta, Diego Andrés. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Das Neves, José. Universidad de Porto; Portugal
Fil: Sosnik, Alejandro Dario. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Sarmento, Bruno. Universidad de Porto; Portugal. Instituto Superior de Ciências da Saúde-Norte; Portugal
description Recently, much attention has been given to pulmonary drug delivery by means of nanosized systems to treat both local and systemic diseases. Among the differentmaterials used for the production of nanocarriers, chitosan enjoys high popularity due to its inherent characteristics such as biocompatibility, biodegradability, and mucoadhesion, among others. Through the modification of chitosan chemical structure, either by the addition of new chemical groups or by the functionalization with ligands, it is possible to obtain derivatives with advantageous and specific characteristics for pulmonary administration. In this paper, we discuss the advantages of using chitosan for nanotechnology-based pulmonary delivery of drugs and summarize the most recent and promising modifications performed to the chitosan molecule in order to improve its characteristics.
publishDate 2011
dc.date.none.fl_str_mv 2011-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/12914
Andrade, Fernanda; Goycoolea, Francisco; Chiappetta, Diego Andrés; Das Neves, José; Sosnik, Alejandro Dario; et al.; Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery; Hindawi Publishing Corporation; International Journal of Carbohydrate Chemistry; 2011; 865704; 10-2011; 1-14
1687-935X
url http://hdl.handle.net/11336/12914
identifier_str_mv Andrade, Fernanda; Goycoolea, Francisco; Chiappetta, Diego Andrés; Das Neves, José; Sosnik, Alejandro Dario; et al.; Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery; Hindawi Publishing Corporation; International Journal of Carbohydrate Chemistry; 2011; 865704; 10-2011; 1-14
1687-935X
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/ijcc/2011/865704/
info:eu-repo/semantics/altIdentifier/doi/10.1155/2011/865704
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614419716243456
score 13.070432

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