Recent Advances in Chitosan Films for Controlled Release of Drugs

Autores
Mengatto, Luciano Nicolas; Helbling, Ignacio Marcelo; Luna, Julio Alberto
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Chitosan is a versatile carrier for biologically active agent from a small molecule such as an antibiotic to macromolecules such as proteins and nucleic acids. In addition, drug delivery devices based on chitosan can be available in a variety of morphologies including films, fibers, nanoparticles and microspheres. Otherwise the inherent advantages of this polymer such as biocompatibility, tissue adhesions and hydrophilic nature, chitosan can be modified to accomplish a specific purpose for example improves release kinetics. In this review are presented and discussed recent patents including three types of chitosan-based film systems for drug delivery: matrix type systems, membrane coated systems and film forming solution. For each one of these systems several examples of manufacture processes, bioactive agents to be delivered and specifics applications were considered. This review highlights the possibilities of use chitosan in an unmodified state and examples of modifications of the polymer backbone.
Fil: Mengatto, Luciano Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Helbling, Ignacio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Luna, Julio Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Materia
CHITOSAN FILM
CHITOSAN MODIFICATION
DRUG DELIVERY
FILM FORMING SOLUTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/273348

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spelling Recent Advances in Chitosan Films for Controlled Release of DrugsMengatto, Luciano NicolasHelbling, Ignacio MarceloLuna, Julio AlbertoCHITOSAN FILMCHITOSAN MODIFICATIONDRUG DELIVERYFILM FORMING SOLUTIONhttps://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/2Chitosan is a versatile carrier for biologically active agent from a small molecule such as an antibiotic to macromolecules such as proteins and nucleic acids. In addition, drug delivery devices based on chitosan can be available in a variety of morphologies including films, fibers, nanoparticles and microspheres. Otherwise the inherent advantages of this polymer such as biocompatibility, tissue adhesions and hydrophilic nature, chitosan can be modified to accomplish a specific purpose for example improves release kinetics. In this review are presented and discussed recent patents including three types of chitosan-based film systems for drug delivery: matrix type systems, membrane coated systems and film forming solution. For each one of these systems several examples of manufacture processes, bioactive agents to be delivered and specifics applications were considered. This review highlights the possibilities of use chitosan in an unmodified state and examples of modifications of the polymer backbone.Fil: Mengatto, Luciano Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Helbling, Ignacio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Luna, Julio Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaBentham Science Publishers2012-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/273348Mengatto, Luciano Nicolas; Helbling, Ignacio Marcelo; Luna, Julio Alberto; Recent Advances in Chitosan Films for Controlled Release of Drugs; Bentham Science Publishers; Recent Patents on Drug Delivery & Formulation; 6; 2; 5-2012; 156-1701872-2113CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.eurekaselect.com/article/42928info:eu-repo/semantics/altIdentifier/doi/10.2174/187221112800672967info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:04:21Zoai:ri.conicet.gov.ar:11336/273348instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:04:21.682CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Recent Advances in Chitosan Films for Controlled Release of Drugs
title Recent Advances in Chitosan Films for Controlled Release of Drugs
spellingShingle Recent Advances in Chitosan Films for Controlled Release of Drugs
Mengatto, Luciano Nicolas
CHITOSAN FILM
CHITOSAN MODIFICATION
DRUG DELIVERY
FILM FORMING SOLUTION
title_short Recent Advances in Chitosan Films for Controlled Release of Drugs
title_full Recent Advances in Chitosan Films for Controlled Release of Drugs
title_fullStr Recent Advances in Chitosan Films for Controlled Release of Drugs
title_full_unstemmed Recent Advances in Chitosan Films for Controlled Release of Drugs
title_sort Recent Advances in Chitosan Films for Controlled Release of Drugs
dc.creator.none.fl_str_mv Mengatto, Luciano Nicolas
Helbling, Ignacio Marcelo
Luna, Julio Alberto
author Mengatto, Luciano Nicolas
author_facet Mengatto, Luciano Nicolas
Helbling, Ignacio Marcelo
Luna, Julio Alberto
author_role author
author2 Helbling, Ignacio Marcelo
Luna, Julio Alberto
author2_role author
author
dc.subject.none.fl_str_mv CHITOSAN FILM
CHITOSAN MODIFICATION
DRUG DELIVERY
FILM FORMING SOLUTION
topic CHITOSAN FILM
CHITOSAN MODIFICATION
DRUG DELIVERY
FILM FORMING SOLUTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Chitosan is a versatile carrier for biologically active agent from a small molecule such as an antibiotic to macromolecules such as proteins and nucleic acids. In addition, drug delivery devices based on chitosan can be available in a variety of morphologies including films, fibers, nanoparticles and microspheres. Otherwise the inherent advantages of this polymer such as biocompatibility, tissue adhesions and hydrophilic nature, chitosan can be modified to accomplish a specific purpose for example improves release kinetics. In this review are presented and discussed recent patents including three types of chitosan-based film systems for drug delivery: matrix type systems, membrane coated systems and film forming solution. For each one of these systems several examples of manufacture processes, bioactive agents to be delivered and specifics applications were considered. This review highlights the possibilities of use chitosan in an unmodified state and examples of modifications of the polymer backbone.
Fil: Mengatto, Luciano Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Helbling, Ignacio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Luna, Julio Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
description Chitosan is a versatile carrier for biologically active agent from a small molecule such as an antibiotic to macromolecules such as proteins and nucleic acids. In addition, drug delivery devices based on chitosan can be available in a variety of morphologies including films, fibers, nanoparticles and microspheres. Otherwise the inherent advantages of this polymer such as biocompatibility, tissue adhesions and hydrophilic nature, chitosan can be modified to accomplish a specific purpose for example improves release kinetics. In this review are presented and discussed recent patents including three types of chitosan-based film systems for drug delivery: matrix type systems, membrane coated systems and film forming solution. For each one of these systems several examples of manufacture processes, bioactive agents to be delivered and specifics applications were considered. This review highlights the possibilities of use chitosan in an unmodified state and examples of modifications of the polymer backbone.
publishDate 2012
dc.date.none.fl_str_mv 2012-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/273348
Mengatto, Luciano Nicolas; Helbling, Ignacio Marcelo; Luna, Julio Alberto; Recent Advances in Chitosan Films for Controlled Release of Drugs; Bentham Science Publishers; Recent Patents on Drug Delivery & Formulation; 6; 2; 5-2012; 156-170
1872-2113
CONICET Digital
CONICET
url http://hdl.handle.net/11336/273348
identifier_str_mv Mengatto, Luciano Nicolas; Helbling, Ignacio Marcelo; Luna, Julio Alberto; Recent Advances in Chitosan Films for Controlled Release of Drugs; Bentham Science Publishers; Recent Patents on Drug Delivery & Formulation; 6; 2; 5-2012; 156-170
1872-2113
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.eurekaselect.com/article/42928
info:eu-repo/semantics/altIdentifier/doi/10.2174/187221112800672967
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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