Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity

Autores
Layana, Carla; Ferrero, Paola Viviana; Rivera Pomar, Rolando Víctor
Año de publicación
2012
Idioma
español castellano
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They are collections of ribonucleoprotein complexes that, in most cases, remain still uncharacterized, except the processing bodies (PBs) and stress granules (SGs), which have been studied (and reviewed) in detail. A challenging prospective is to know how many different classes of foci exist, which functions they support, how are they formed, and how do they relate one to each other. Here, we present an update of the component of the different granules, a possible function, and hypothesis on their in vivo dynamics related to translational control.
Facultad de Ciencias Exactas
Materia
Ciencias Exactas
biochemistry
biodiversity
cell cycle
eukaryote
polysome
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/3.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/38256
Acceder
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network_acronym_str SEDICI
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network_name_str SEDICI (UNLP)
spelling Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversityLayana, CarlaFerrero, Paola VivianaRivera Pomar, Rolando VíctorCiencias Exactasbiochemistrybiodiversitycell cycleeukaryotepolysomeThe life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They are collections of ribonucleoprotein complexes that, in most cases, remain still uncharacterized, except the processing bodies (PBs) and stress granules (SGs), which have been studied (and reviewed) in detail. A challenging prospective is to know how many different classes of foci exist, which functions they support, how are they formed, and how do they relate one to each other. Here, we present an update of the component of the different granules, a possible function, and hypothesis on their <i>in vivo</i> dynamics related to translational control.Facultad de Ciencias Exactas2012info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/38256spainfo:eu-repo/semantics/altIdentifier/url/http://www.hindawi.com/journals/ijg/2012/504292/info:eu-repo/semantics/altIdentifier/issn/1531-6912info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/504292info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/Creative Commons Attribution 3.0 Unported (CC BY 3.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-10-22T16:38:40Zoai:sedici.unlp.edu.ar:10915/38256Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-10-22 16:38:40.9SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity
title Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity
spellingShingle Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity
Layana, Carla
Ciencias Exactas
biochemistry
biodiversity
cell cycle
eukaryote
polysome
title_short Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity
title_full Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity
title_fullStr Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity
title_full_unstemmed Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity
title_sort Cytoplasmic ribonucleoprotein foci in eukaryotes: hotspots of bio(chemical)diversity
dc.creator.none.fl_str_mv Layana, Carla
Ferrero, Paola Viviana
Rivera Pomar, Rolando Víctor
author Layana, Carla
author_facet Layana, Carla
Ferrero, Paola Viviana
Rivera Pomar, Rolando Víctor
author_role author
author2 Ferrero, Paola Viviana
Rivera Pomar, Rolando Víctor
author2_role author
author
dc.subject.none.fl_str_mv Ciencias Exactas
biochemistry
biodiversity
cell cycle
eukaryote
polysome
topic Ciencias Exactas
biochemistry
biodiversity
cell cycle
eukaryote
polysome
dc.description.none.fl_txt_mv The life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They are collections of ribonucleoprotein complexes that, in most cases, remain still uncharacterized, except the processing bodies (PBs) and stress granules (SGs), which have been studied (and reviewed) in detail. A challenging prospective is to know how many different classes of foci exist, which functions they support, how are they formed, and how do they relate one to each other. Here, we present an update of the component of the different granules, a possible function, and hypothesis on their <i>in vivo</i> dynamics related to translational control.
Facultad de Ciencias Exactas
description The life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They are collections of ribonucleoprotein complexes that, in most cases, remain still uncharacterized, except the processing bodies (PBs) and stress granules (SGs), which have been studied (and reviewed) in detail. A challenging prospective is to know how many different classes of foci exist, which functions they support, how are they formed, and how do they relate one to each other. Here, we present an update of the component of the different granules, a possible function, and hypothesis on their <i>in vivo</i> dynamics related to translational control.
publishDate 2012
dc.date.none.fl_str_mv 2012
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/38256
url http://sedici.unlp.edu.ar/handle/10915/38256
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.hindawi.com/journals/ijg/2012/504292/
info:eu-repo/semantics/altIdentifier/issn/1531-6912
info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/504292
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/3.0/
Creative Commons Attribution 3.0 Unported (CC BY 3.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/3.0/
Creative Commons Attribution 3.0 Unported (CC BY 3.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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