Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity

Autores
Layana, Carla; Ferrero, Paola Viviana; Rivera Pomar, Rolando
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They are collections of ribonucleoprotein complexes that, in most cases, remain still uncharacterized, except the processing bodies (PBs) and stress granules (SGs), which have been studied (and reviewed) in detail. A challenging prospective is to know how many different classes of foci exist, which functions they support, how are they formed, and how do they relate one to each other. Here, we present an update of the component of the different granules, a possible function, and hypothesis on their in vivo dynamics related to translational control.
Fil: Layana, Carla. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Ferrero, Paola Viviana. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Rivera Pomar, Rolando. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Materia
eIF4E
processing bodies
stress granules
Drosophila
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/196183
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversityLayana, CarlaFerrero, Paola VivianaRivera Pomar, RolandoeIF4Eprocessing bodiesstress granulesDrosophilahttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They are collections of ribonucleoprotein complexes that, in most cases, remain still uncharacterized, except the processing bodies (PBs) and stress granules (SGs), which have been studied (and reviewed) in detail. A challenging prospective is to know how many different classes of foci exist, which functions they support, how are they formed, and how do they relate one to each other. Here, we present an update of the component of the different granules, a possible function, and hypothesis on their in vivo dynamics related to translational control.Fil: Layana, Carla. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Ferrero, Paola Viviana. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Rivera Pomar, Rolando. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaHindawi Publishing Corporation2011-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/196183Layana, Carla; Ferrero, Paola Viviana; Rivera Pomar, Rolando; Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity; Hindawi Publishing Corporation; Comparative And Functional Genomics; 12-2011; 1-121531-69121532-6268CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/ijg/2012/504292/info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/504292info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:59:00Zoai:ri.conicet.gov.ar:11336/196183instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:59:00.558CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity
title Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity
spellingShingle Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity
Layana, Carla
eIF4E
processing bodies
stress granules
Drosophila
title_short Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity
title_full Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity
title_fullStr Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity
title_full_unstemmed Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity
title_sort Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity
dc.creator.none.fl_str_mv Layana, Carla
Ferrero, Paola Viviana
Rivera Pomar, Rolando
author Layana, Carla
author_facet Layana, Carla
Ferrero, Paola Viviana
Rivera Pomar, Rolando
author_role author
author2 Ferrero, Paola Viviana
Rivera Pomar, Rolando
author2_role author
author
dc.subject.none.fl_str_mv eIF4E
processing bodies
stress granules
Drosophila
topic eIF4E
processing bodies
stress granules
Drosophila
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They are collections of ribonucleoprotein complexes that, in most cases, remain still uncharacterized, except the processing bodies (PBs) and stress granules (SGs), which have been studied (and reviewed) in detail. A challenging prospective is to know how many different classes of foci exist, which functions they support, how are they formed, and how do they relate one to each other. Here, we present an update of the component of the different granules, a possible function, and hypothesis on their in vivo dynamics related to translational control.
Fil: Layana, Carla. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Ferrero, Paola Viviana. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Rivera Pomar, Rolando. Universidad Nacional de La Plata. Centro Regional de Estudios Genómicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
description The life of an mRNA from transcription to degradation offers multiple control check points that regulate gene expression. Transcription, splicing, and translation have been widely studied for many years; however, in recent years, new layers of posttranscriptional and posttranslational control have been uncovered. They involve the regulation of the metabolism of mRNA in cytoplasmic foci. They are collections of ribonucleoprotein complexes that, in most cases, remain still uncharacterized, except the processing bodies (PBs) and stress granules (SGs), which have been studied (and reviewed) in detail. A challenging prospective is to know how many different classes of foci exist, which functions they support, how are they formed, and how do they relate one to each other. Here, we present an update of the component of the different granules, a possible function, and hypothesis on their in vivo dynamics related to translational control.
publishDate 2011
dc.date.none.fl_str_mv 2011-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/196183
Layana, Carla; Ferrero, Paola Viviana; Rivera Pomar, Rolando; Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity; Hindawi Publishing Corporation; Comparative And Functional Genomics; 12-2011; 1-12
1531-6912
1532-6268
CONICET Digital
CONICET
url http://hdl.handle.net/11336/196183
identifier_str_mv Layana, Carla; Ferrero, Paola Viviana; Rivera Pomar, Rolando; Cytoplasmic ribonucleoprotein foci in eukaryotes: Hotspots of bio(chemical)diversity; Hindawi Publishing Corporation; Comparative And Functional Genomics; 12-2011; 1-12
1531-6912
1532-6268
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/ijg/2012/504292/
info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/504292
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269555434455040
score 13.13397

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