Potential medicinal effects and applications of stevia constituents

Autores
Talevi, Alan
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The application of stevia glycosides in the food industry has grown steadily in the last two decades. Besides the use of its constituents as natural sweeteners, increasing attention has been given to their potential health benefits and therapeutic applications. Whereas in some cases clinical studies have been realized (prominently, to investigate its hypoglycemic and antihypertensive activity) many of them have failed to cover the expectations from preclinical investigations. Here, we review current knowledge on stevia constituents’ pharmacokinetics (both in rodents and in humans) and some of the most profusely investigated potential medical/health-related applications: i.e. diabetes and metabolic syndrome, hypertension, antimicrobial and anticancer activity. The outcome of available clinical studies and the perspectives of Stevia therapeutic uses are discussed in connection with pharmacokinetics knowledge.
Laboratorio de Investigación y Desarrollo de Bioactivos
Materia
Ciencias Médicas
Stevia
Stevia rebaudiana
Steviosides Pharmacology
Medical uses
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/134981
Acceder
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network_name_str SEDICI (UNLP)
spelling Potential medicinal effects and applications of stevia constituentsTalevi, AlanCiencias MédicasSteviaStevia rebaudianaSteviosides PharmacologyMedical usesThe application of stevia glycosides in the food industry has grown steadily in the last two decades. Besides the use of its constituents as natural sweeteners, increasing attention has been given to their potential health benefits and therapeutic applications. Whereas in some cases clinical studies have been realized (prominently, to investigate its hypoglycemic and antihypertensive activity) many of them have failed to cover the expectations from preclinical investigations. Here, we review current knowledge on stevia constituents’ pharmacokinetics (both in rodents and in humans) and some of the most profusely investigated potential medical/health-related applications: i.e. diabetes and metabolic syndrome, hypertension, antimicrobial and anticancer activity. The outcome of available clinical studies and the perspectives of Stevia therapeutic uses are discussed in connection with pharmacokinetics knowledge.Laboratorio de Investigación y Desarrollo de Bioactivos2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf161-178http://sedici.unlp.edu.ar/handle/10915/134981enginfo:eu-repo/semantics/altIdentifier/issn/1568-7767info:eu-repo/semantics/altIdentifier/issn/1572-980Xinfo:eu-repo/semantics/altIdentifier/doi/10.1007/s11101-021-09753-5info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:04:23Zoai:sedici.unlp.edu.ar:10915/134981Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:04:23.329SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Potential medicinal effects and applications of stevia constituents
title Potential medicinal effects and applications of stevia constituents
spellingShingle Potential medicinal effects and applications of stevia constituents
Talevi, Alan
Ciencias Médicas
Stevia
Stevia rebaudiana
Steviosides Pharmacology
Medical uses
title_short Potential medicinal effects and applications of stevia constituents
title_full Potential medicinal effects and applications of stevia constituents
title_fullStr Potential medicinal effects and applications of stevia constituents
title_full_unstemmed Potential medicinal effects and applications of stevia constituents
title_sort Potential medicinal effects and applications of stevia constituents
dc.creator.none.fl_str_mv Talevi, Alan
author Talevi, Alan
author_facet Talevi, Alan
author_role author
dc.subject.none.fl_str_mv Ciencias Médicas
Stevia
Stevia rebaudiana
Steviosides Pharmacology
Medical uses
topic Ciencias Médicas
Stevia
Stevia rebaudiana
Steviosides Pharmacology
Medical uses
dc.description.none.fl_txt_mv The application of stevia glycosides in the food industry has grown steadily in the last two decades. Besides the use of its constituents as natural sweeteners, increasing attention has been given to their potential health benefits and therapeutic applications. Whereas in some cases clinical studies have been realized (prominently, to investigate its hypoglycemic and antihypertensive activity) many of them have failed to cover the expectations from preclinical investigations. Here, we review current knowledge on stevia constituents’ pharmacokinetics (both in rodents and in humans) and some of the most profusely investigated potential medical/health-related applications: i.e. diabetes and metabolic syndrome, hypertension, antimicrobial and anticancer activity. The outcome of available clinical studies and the perspectives of Stevia therapeutic uses are discussed in connection with pharmacokinetics knowledge.
Laboratorio de Investigación y Desarrollo de Bioactivos
description The application of stevia glycosides in the food industry has grown steadily in the last two decades. Besides the use of its constituents as natural sweeteners, increasing attention has been given to their potential health benefits and therapeutic applications. Whereas in some cases clinical studies have been realized (prominently, to investigate its hypoglycemic and antihypertensive activity) many of them have failed to cover the expectations from preclinical investigations. Here, we review current knowledge on stevia constituents’ pharmacokinetics (both in rodents and in humans) and some of the most profusely investigated potential medical/health-related applications: i.e. diabetes and metabolic syndrome, hypertension, antimicrobial and anticancer activity. The outcome of available clinical studies and the perspectives of Stevia therapeutic uses are discussed in connection with pharmacokinetics knowledge.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/134981
url http://sedici.unlp.edu.ar/handle/10915/134981
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/issn/1572-980X
info:eu-repo/semantics/altIdentifier/doi/10.1007/s11101-021-09753-5
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
161-178
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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