Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice

Autores
Del Coco, Valeria Fernanda; Sparo, Mónica Delfina; Sidoti, Alicia; Santin, Mónica; Basualdo Farjat, Juan Ángel; Córdoba, María Alejandra
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Cryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. However, there is a lack of completely efficient therapy available. Probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. This study investigated the effects of administration of probiotic Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in immunosuppressed mice. Effects on C. parvum infection at the intestinal mucosa were studied and scored at each portion of the gut. It was demonstrated that Ef CECT 7121 interfered with C. parvum infection when both probiotic and parasite were present in the same intestinal location suggesting that Ef CECT 7121 supplementation can alleviate the negative effects of C. parvum infection.
Facultad de Ciencias Médicas
Facultad de Ciencias Exactas
Comisión de Investigaciones Científicas de la provincia de Buenos Aires
Centro Universitario de Estudios Microbiológicos y Parasitológicos
Materia
Ciencias Médicas
Cryptosporidium
Probiotics
Immunosuppressed mice
Enterococcus faecalis CECT7121
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/102982
Acceder
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network_name_str SEDICI (UNLP)
spelling Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in miceDel Coco, Valeria FernandaSparo, Mónica DelfinaSidoti, AliciaSantin, MónicaBasualdo Farjat, Juan ÁngelCórdoba, María AlejandraCiencias MédicasCryptosporidiumProbioticsImmunosuppressed miceEnterococcus faecalis CECT7121Cryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. However, there is a lack of completely efficient therapy available. Probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. This study investigated the effects of administration of probiotic Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in immunosuppressed mice. Effects on C. parvum infection at the intestinal mucosa were studied and scored at each portion of the gut. It was demonstrated that Ef CECT 7121 interfered with C. parvum infection when both probiotic and parasite were present in the same intestinal location suggesting that Ef CECT 7121 supplementation can alleviate the negative effects of C. parvum infection.Facultad de Ciencias MédicasFacultad de Ciencias ExactasComisión de Investigaciones Científicas de la provincia de Buenos AiresCentro Universitario de Estudios Microbiológicos y Parasitológicos2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf3239-3244http://sedici.unlp.edu.ar/handle/10915/102982enginfo:eu-repo/semantics/altIdentifier/issn/1432-1955info:eu-repo/semantics/altIdentifier/doi/10.1007/s00436-016-5087-1info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-17T10:05:03Zoai:sedici.unlp.edu.ar:10915/102982Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-17 10:05:04.275SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
title Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
spellingShingle Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
Del Coco, Valeria Fernanda
Ciencias Médicas
Cryptosporidium
Probiotics
Immunosuppressed mice
Enterococcus faecalis CECT7121
title_short Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
title_full Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
title_fullStr Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
title_full_unstemmed Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
title_sort Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
dc.creator.none.fl_str_mv Del Coco, Valeria Fernanda
Sparo, Mónica Delfina
Sidoti, Alicia
Santin, Mónica
Basualdo Farjat, Juan Ángel
Córdoba, María Alejandra
author Del Coco, Valeria Fernanda
author_facet Del Coco, Valeria Fernanda
Sparo, Mónica Delfina
Sidoti, Alicia
Santin, Mónica
Basualdo Farjat, Juan Ángel
Córdoba, María Alejandra
author_role author
author2 Sparo, Mónica Delfina
Sidoti, Alicia
Santin, Mónica
Basualdo Farjat, Juan Ángel
Córdoba, María Alejandra
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Médicas
Cryptosporidium
Probiotics
Immunosuppressed mice
Enterococcus faecalis CECT7121
topic Ciencias Médicas
Cryptosporidium
Probiotics
Immunosuppressed mice
Enterococcus faecalis CECT7121
dc.description.none.fl_txt_mv Cryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. However, there is a lack of completely efficient therapy available. Probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. This study investigated the effects of administration of probiotic Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in immunosuppressed mice. Effects on C. parvum infection at the intestinal mucosa were studied and scored at each portion of the gut. It was demonstrated that Ef CECT 7121 interfered with C. parvum infection when both probiotic and parasite were present in the same intestinal location suggesting that Ef CECT 7121 supplementation can alleviate the negative effects of C. parvum infection.
Facultad de Ciencias Médicas
Facultad de Ciencias Exactas
Comisión de Investigaciones Científicas de la provincia de Buenos Aires
Centro Universitario de Estudios Microbiológicos y Parasitológicos
description Cryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. However, there is a lack of completely efficient therapy available. Probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. This study investigated the effects of administration of probiotic Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in immunosuppressed mice. Effects on C. parvum infection at the intestinal mucosa were studied and scored at each portion of the gut. It was demonstrated that Ef CECT 7121 interfered with C. parvum infection when both probiotic and parasite were present in the same intestinal location suggesting that Ef CECT 7121 supplementation can alleviate the negative effects of C. parvum infection.
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/102982
url http://sedici.unlp.edu.ar/handle/10915/102982
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1432-1955
info:eu-repo/semantics/altIdentifier/doi/10.1007/s00436-016-5087-1
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
3239-3244
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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