Current strategies to prevent ishcemia reperfusion injury in organ transplantation
- Autores
- Stringa, Pablo Luis; Rumbo, Martín
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- reseña artículo
- Estado
- versión publicada
- Descripción
- Solid organ transplantation is inherently associated to ischemia reperfusion injury (IRI) since the operative procedure always impliesthe harvesting, preservation and implantation of the organ,whichresult in several hours of ischemia followed by reperfusion. Several strategies have been proposed to mitigate IRI in organ transplantation.However, most of them are in experimental phases and currently few are implemented in the clinical field. These strategies can be applied in 3 different stages of the transplantation procedure: on the organ donor, known as donor pre-treatment; during preservation, when ischemic organ is waiting to be implanted in the recipient or on the transplant recipient. In the present review, we will discuss the different approaches to control IRI damage in solid organ transplantation and the rationale behind them.
Facultad de Ciencias Exactas
Instituto de Estudios Inmunológicos y Fisiopatológicos - Materia
-
Medicina
Ciencias Exactas
Solid organ transplantation
Ischemia
Reperfusion
Prevention - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by-nc-sa/4.0/
- Repositorio
.jpg)
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/102619
Ver los metadatos del registro completo
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Current strategies to prevent ishcemia reperfusion injury in organ transplantationStringa, Pablo LuisRumbo, MartínMedicinaCiencias ExactasSolid organ transplantationIschemiaReperfusionPreventionSolid organ transplantation is inherently associated to ischemia reperfusion injury (IRI) since the operative procedure always impliesthe harvesting, preservation and implantation of the organ,whichresult in several hours of ischemia followed by reperfusion. Several strategies have been proposed to mitigate IRI in organ transplantation.However, most of them are in experimental phases and currently few are implemented in the clinical field. These strategies can be applied in 3 different stages of the transplantation procedure: on the organ donor, known as donor pre-treatment; during preservation, when ischemic organ is waiting to be implanted in the recipient or on the transplant recipient. In the present review, we will discuss the different approaches to control IRI damage in solid organ transplantation and the rationale behind them.Facultad de Ciencias ExactasInstituto de Estudios Inmunológicos y Fisiopatológicos2014-07info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionRevisionhttp://purl.org/coar/resource_type/c_dcae04bcinfo:ar-repo/semantics/resenaArticuloapplication/pdf44-59http://sedici.unlp.edu.ar/handle/10915/102619enginfo:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/33219info:eu-repo/semantics/altIdentifier/url/http://pmr.safisiol.org.ar/archive/id/65info:eu-repo/semantics/altIdentifier/issn/1669-5410info:eu-repo/semantics/altIdentifier/hdl/11336/33219info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T10:52:16Zoai:sedici.unlp.edu.ar:10915/102619Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 10:52:17.175SEDICI (UNLP) - Universidad Nacional de La Platafalse |
| dc.title.none.fl_str_mv |
Current strategies to prevent ishcemia reperfusion injury in organ transplantation |
| title |
Current strategies to prevent ishcemia reperfusion injury in organ transplantation |
| spellingShingle |
Current strategies to prevent ishcemia reperfusion injury in organ transplantation Stringa, Pablo Luis Medicina Ciencias Exactas Solid organ transplantation Ischemia Reperfusion Prevention |
| title_short |
Current strategies to prevent ishcemia reperfusion injury in organ transplantation |
| title_full |
Current strategies to prevent ishcemia reperfusion injury in organ transplantation |
| title_fullStr |
Current strategies to prevent ishcemia reperfusion injury in organ transplantation |
| title_full_unstemmed |
Current strategies to prevent ishcemia reperfusion injury in organ transplantation |
| title_sort |
Current strategies to prevent ishcemia reperfusion injury in organ transplantation |
| dc.creator.none.fl_str_mv |
Stringa, Pablo Luis Rumbo, Martín |
| author |
Stringa, Pablo Luis |
| author_facet |
Stringa, Pablo Luis Rumbo, Martín |
| author_role |
author |
| author2 |
Rumbo, Martín |
| author2_role |
author |
| dc.subject.none.fl_str_mv |
Medicina Ciencias Exactas Solid organ transplantation Ischemia Reperfusion Prevention |
| topic |
Medicina Ciencias Exactas Solid organ transplantation Ischemia Reperfusion Prevention |
| dc.description.none.fl_txt_mv |
Solid organ transplantation is inherently associated to ischemia reperfusion injury (IRI) since the operative procedure always impliesthe harvesting, preservation and implantation of the organ,whichresult in several hours of ischemia followed by reperfusion. Several strategies have been proposed to mitigate IRI in organ transplantation.However, most of them are in experimental phases and currently few are implemented in the clinical field. These strategies can be applied in 3 different stages of the transplantation procedure: on the organ donor, known as donor pre-treatment; during preservation, when ischemic organ is waiting to be implanted in the recipient or on the transplant recipient. In the present review, we will discuss the different approaches to control IRI damage in solid organ transplantation and the rationale behind them. Facultad de Ciencias Exactas Instituto de Estudios Inmunológicos y Fisiopatológicos |
| description |
Solid organ transplantation is inherently associated to ischemia reperfusion injury (IRI) since the operative procedure always impliesthe harvesting, preservation and implantation of the organ,whichresult in several hours of ischemia followed by reperfusion. Several strategies have been proposed to mitigate IRI in organ transplantation.However, most of them are in experimental phases and currently few are implemented in the clinical field. These strategies can be applied in 3 different stages of the transplantation procedure: on the organ donor, known as donor pre-treatment; during preservation, when ischemic organ is waiting to be implanted in the recipient or on the transplant recipient. In the present review, we will discuss the different approaches to control IRI damage in solid organ transplantation and the rationale behind them. |
| publishDate |
2014 |
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2014-07 |
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info:eu-repo/semantics/review info:eu-repo/semantics/publishedVersion Revision http://purl.org/coar/resource_type/c_dcae04bc info:ar-repo/semantics/resenaArticulo |
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review |
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publishedVersion |
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http://sedici.unlp.edu.ar/handle/10915/102619 |
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eng |
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