The Simons Genome Diversity Project : 300 genomes from 142 diverse populations.
- Autores
- Bravi, Claudio Marcelo
- Año de publicación
- 2016
- Idioma
- español castellano
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergence. We show that the ancestors of some pairs of present-day human populations were substantially separated by 100,000 years ago, well before the archaeologically attested onset of behavioural modernity. We also demonstrate that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans.
Facultad de Ciencias Naturales y Museo - Materia
-
Ciencias Médicas
Simons Genome Diversity Project
Human genome variation
Divergence - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by-nc-sa/4.0/
- Repositorio
.jpg)
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/107824
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The Simons Genome Diversity Project : 300 genomes from 142 diverse populations.Bravi, Claudio MarceloCiencias MédicasSimons Genome Diversity ProjectHuman genome variationDivergenceHere we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergence. We show that the ancestors of some pairs of present-day human populations were substantially separated by 100,000 years ago, well before the archaeologically attested onset of behavioural modernity. We also demonstrate that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans.Facultad de Ciencias Naturales y Museo2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/107824spainfo:eu-repo/semantics/altIdentifier/url/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5161557&blobtype=pdfinfo:eu-repo/semantics/altIdentifier/issn/1476-4687info:eu-repo/semantics/altIdentifier/pmid/27654912info:eu-repo/semantics/altIdentifier/doi/10.1038/nature18964info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:23:56Zoai:sedici.unlp.edu.ar:10915/107824Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:23:56.968SEDICI (UNLP) - Universidad Nacional de La Platafalse |
| dc.title.none.fl_str_mv |
The Simons Genome Diversity Project : 300 genomes from 142 diverse populations. |
| title |
The Simons Genome Diversity Project : 300 genomes from 142 diverse populations. |
| spellingShingle |
The Simons Genome Diversity Project : 300 genomes from 142 diverse populations. Bravi, Claudio Marcelo Ciencias Médicas Simons Genome Diversity Project Human genome variation Divergence |
| title_short |
The Simons Genome Diversity Project : 300 genomes from 142 diverse populations. |
| title_full |
The Simons Genome Diversity Project : 300 genomes from 142 diverse populations. |
| title_fullStr |
The Simons Genome Diversity Project : 300 genomes from 142 diverse populations. |
| title_full_unstemmed |
The Simons Genome Diversity Project : 300 genomes from 142 diverse populations. |
| title_sort |
The Simons Genome Diversity Project : 300 genomes from 142 diverse populations. |
| dc.creator.none.fl_str_mv |
Bravi, Claudio Marcelo |
| author |
Bravi, Claudio Marcelo |
| author_facet |
Bravi, Claudio Marcelo |
| author_role |
author |
| dc.subject.none.fl_str_mv |
Ciencias Médicas Simons Genome Diversity Project Human genome variation Divergence |
| topic |
Ciencias Médicas Simons Genome Diversity Project Human genome variation Divergence |
| dc.description.none.fl_txt_mv |
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergence. We show that the ancestors of some pairs of present-day human populations were substantially separated by 100,000 years ago, well before the archaeologically attested onset of behavioural modernity. We also demonstrate that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans. Facultad de Ciencias Naturales y Museo |
| description |
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergence. We show that the ancestors of some pairs of present-day human populations were substantially separated by 100,000 years ago, well before the archaeologically attested onset of behavioural modernity. We also demonstrate that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans. |
| publishDate |
2016 |
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2016 |
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