Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering
- Autores
- Massone, Agustina
- Año de publicación
- 2017
- Idioma
- inglés
- Tipo de recurso
- tesis de grado
- Estado
- versión borrador
- Colaborador/a o director/a de tesis
- Liverani, Liliana
- Descripción
- Nanofibers and nanomaterials are potentially recent additions to materials in relation to tissue engineering (TE). TE involves the regeneration of biological tissues, which are damaged, using cells with the aid of supporting structures and biomolecules. Mimicking the architecture and functions of extracellular matrix is one of the challenges for TE. Conventional treatments, such as transplantations and the use of mechanical assist devices, could be replaced with this approach. Electrospinning is a versatile and simple technique to produce polymer fibers with diameters varying from 5 nm to 5 μm, which can mimic the extracellular matrix. This characteristic stimulates the expression of specific signals and, in combination with growth factors and proteins, has an important influence in cellular activity. Blending synthetic with natural polymers, combine the advantages of both leading to good biodegradation and mechanical properties, and excellent cell adhesion and growth. In this work, it is presented the preparation and characterization of natural polymer (zein)-based nanofibrous scaffolds obtained through electrospinning technique. The processing parameters were adjusted to obtain randomly-oriented nanofibrous mats. Although the basic principles of the technique are simple, the many factors and parameters involved in it make the process complex. Through the analysis of testing results, it was found that the blend of zein with synthetic polymers improve in many folds its properties. The nanofibrous mats are of great interest for its applications in tissue engineering.
Fil: Massone, Agustina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería; Argentina - Materia
-
Nanofibras
Nanomateriales
Ingeniería de tejidos
Ingeniería de tejidos (TE)
Electrospinning
Polímeros naturales - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/4.0/
- Repositorio
- Institución
- Universidad Nacional de Mar del Plata. Facultad de Ingeniería
- OAI Identificador
- oai:rinfi.fi.mdp.edu.ar:123456789/311
Ver los metadatos del registro completo
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Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineeringMassone, AgustinaNanofibrasNanomaterialesIngeniería de tejidosIngeniería de tejidos (TE)ElectrospinningPolímeros naturalesNanofibers and nanomaterials are potentially recent additions to materials in relation to tissue engineering (TE). TE involves the regeneration of biological tissues, which are damaged, using cells with the aid of supporting structures and biomolecules. Mimicking the architecture and functions of extracellular matrix is one of the challenges for TE. Conventional treatments, such as transplantations and the use of mechanical assist devices, could be replaced with this approach. Electrospinning is a versatile and simple technique to produce polymer fibers with diameters varying from 5 nm to 5 μm, which can mimic the extracellular matrix. This characteristic stimulates the expression of specific signals and, in combination with growth factors and proteins, has an important influence in cellular activity. Blending synthetic with natural polymers, combine the advantages of both leading to good biodegradation and mechanical properties, and excellent cell adhesion and growth. In this work, it is presented the preparation and characterization of natural polymer (zein)-based nanofibrous scaffolds obtained through electrospinning technique. The processing parameters were adjusted to obtain randomly-oriented nanofibrous mats. Although the basic principles of the technique are simple, the many factors and parameters involved in it make the process complex. Through the analysis of testing results, it was found that the blend of zein with synthetic polymers improve in many folds its properties. The nanofibrous mats are of great interest for its applications in tissue engineering.Fil: Massone, Agustina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería; ArgentinaUniversidad Nacional de Mar del Plata. Facultad de Ingeniería. ArgentinaLiverani, Liliana2017-03-02Thesisinfo:eu-repo/semantics/draftinfo:eu-repo/semantics/bachelorThesishttp://purl.org/coar/resource_type/c_7a1finfo:ar-repo/semantics/tesisDeGradoapplication/pdfhttp://rinfi.fi.mdp.edu.ar/xmlui/handle/123456789/311enginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/reponame:Repositorio Institucional Facultad de Ingeniería - UNMDPinstname:Universidad Nacional de Mar del Plata. Facultad de Ingeniería2025-09-29T15:02:38Zoai:rinfi.fi.mdp.edu.ar:123456789/311instacron:FI-UNMDPInstitucionalhttps://rinfi.fi.mdp.edu.ar/Universidad públicahttps://www.fi.mdp.edu.ar/https://rinfi.fi.mdp.edu.ar/oai/snrdjosemrvs@fi.mdp.edu.arArgentinaopendoar:2025-09-29 15:02:38.857Repositorio Institucional Facultad de Ingeniería - UNMDP - Universidad Nacional de Mar del Plata. Facultad de Ingenieríafalse |
dc.title.none.fl_str_mv |
Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering |
title |
Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering |
spellingShingle |
Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering Massone, Agustina Nanofibras Nanomateriales Ingeniería de tejidos Ingeniería de tejidos (TE) Electrospinning Polímeros naturales |
title_short |
Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering |
title_full |
Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering |
title_fullStr |
Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering |
title_full_unstemmed |
Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering |
title_sort |
Fabrication and characterization of electrospun zein-based scaffolds for soft tissue engineering |
dc.creator.none.fl_str_mv |
Massone, Agustina |
author |
Massone, Agustina |
author_facet |
Massone, Agustina |
author_role |
author |
dc.contributor.none.fl_str_mv |
Liverani, Liliana |
dc.subject.none.fl_str_mv |
Nanofibras Nanomateriales Ingeniería de tejidos Ingeniería de tejidos (TE) Electrospinning Polímeros naturales |
topic |
Nanofibras Nanomateriales Ingeniería de tejidos Ingeniería de tejidos (TE) Electrospinning Polímeros naturales |
dc.description.none.fl_txt_mv |
Nanofibers and nanomaterials are potentially recent additions to materials in relation to tissue engineering (TE). TE involves the regeneration of biological tissues, which are damaged, using cells with the aid of supporting structures and biomolecules. Mimicking the architecture and functions of extracellular matrix is one of the challenges for TE. Conventional treatments, such as transplantations and the use of mechanical assist devices, could be replaced with this approach. Electrospinning is a versatile and simple technique to produce polymer fibers with diameters varying from 5 nm to 5 μm, which can mimic the extracellular matrix. This characteristic stimulates the expression of specific signals and, in combination with growth factors and proteins, has an important influence in cellular activity. Blending synthetic with natural polymers, combine the advantages of both leading to good biodegradation and mechanical properties, and excellent cell adhesion and growth. In this work, it is presented the preparation and characterization of natural polymer (zein)-based nanofibrous scaffolds obtained through electrospinning technique. The processing parameters were adjusted to obtain randomly-oriented nanofibrous mats. Although the basic principles of the technique are simple, the many factors and parameters involved in it make the process complex. Through the analysis of testing results, it was found that the blend of zein with synthetic polymers improve in many folds its properties. The nanofibrous mats are of great interest for its applications in tissue engineering. Fil: Massone, Agustina. Universidad Nacional de Mar del Plata. Facultad de Ingeniería; Argentina |
description |
Nanofibers and nanomaterials are potentially recent additions to materials in relation to tissue engineering (TE). TE involves the regeneration of biological tissues, which are damaged, using cells with the aid of supporting structures and biomolecules. Mimicking the architecture and functions of extracellular matrix is one of the challenges for TE. Conventional treatments, such as transplantations and the use of mechanical assist devices, could be replaced with this approach. Electrospinning is a versatile and simple technique to produce polymer fibers with diameters varying from 5 nm to 5 μm, which can mimic the extracellular matrix. This characteristic stimulates the expression of specific signals and, in combination with growth factors and proteins, has an important influence in cellular activity. Blending synthetic with natural polymers, combine the advantages of both leading to good biodegradation and mechanical properties, and excellent cell adhesion and growth. In this work, it is presented the preparation and characterization of natural polymer (zein)-based nanofibrous scaffolds obtained through electrospinning technique. The processing parameters were adjusted to obtain randomly-oriented nanofibrous mats. Although the basic principles of the technique are simple, the many factors and parameters involved in it make the process complex. Through the analysis of testing results, it was found that the blend of zein with synthetic polymers improve in many folds its properties. The nanofibrous mats are of great interest for its applications in tissue engineering. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-03-02 |
dc.type.none.fl_str_mv |
Thesis info:eu-repo/semantics/draft info:eu-repo/semantics/bachelorThesis http://purl.org/coar/resource_type/c_7a1f info:ar-repo/semantics/tesisDeGrado |
status_str |
draft |
format |
bachelorThesis |
dc.identifier.none.fl_str_mv |
http://rinfi.fi.mdp.edu.ar/xmlui/handle/123456789/311 |
url |
http://rinfi.fi.mdp.edu.ar/xmlui/handle/123456789/311 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0/ |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Argentina |
publisher.none.fl_str_mv |
Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Argentina |
dc.source.none.fl_str_mv |
reponame:Repositorio Institucional Facultad de Ingeniería - UNMDP instname:Universidad Nacional de Mar del Plata. Facultad de Ingeniería |
reponame_str |
Repositorio Institucional Facultad de Ingeniería - UNMDP |
collection |
Repositorio Institucional Facultad de Ingeniería - UNMDP |
instname_str |
Universidad Nacional de Mar del Plata. Facultad de Ingeniería |
repository.name.fl_str_mv |
Repositorio Institucional Facultad de Ingeniería - UNMDP - Universidad Nacional de Mar del Plata. Facultad de Ingeniería |
repository.mail.fl_str_mv |
josemrvs@fi.mdp.edu.ar |
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1844623360031457280 |
score |
12.559606 |