Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?

Autores
Dadam, Florencia; Rivarola, María Angélica; Vivas, Laura; Caeiro, Ximena E.
Año de publicación
2020
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Fil: Dadam, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Fil: Rivarola, María Angélica. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Fil: Vivas, L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.
Fil: Caeiro, Ximena E. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Evidence demonstrate that the pressor response to AngII infusion is sexually dimorphic under physiological and pathophysiological circumstances. But why do male and female show differences in rennin angiotensin system (RAS) activation and inhibition? Sex steroids can induce organizational (long-lasting or permanent) effect during critical periods of development but can also impart (temporary or reversible) activational effects. Furthermore, males and females also carry different sex chromosome complements (SCC:XY/XX) and thus are influenced throughout life by different genomes. Previous evidence demonstrates a modulatory effect of SCC in RAS receptor expression (brain/renal), as well as in the AngII sexually dimorphic bradycardic barroreflex and hypertensive responses. In the present study we evaluated the involvement of SCC, organizational and activational hormone effect on changes in mean arterial pressure (MAP) in a 10 min AngII infusion protocol.
Fil: Dadam, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Fil: Rivarola, María Angélica. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Fil: Vivas, L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.
Fil: Caeiro, Ximena E. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Otras Ciencias Biológicas
Materia
Presión arterial
Renin angiotensin system
Sex chromosome complement
Sex hormones
Four core genotypes mouse model
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Repositorio
Repositorio Digital Universitario (UNC)
Institución
Universidad Nacional de Córdoba
OAI Identificador
oai:rdu.unc.edu.ar:11086/560965
Acceder
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oai_identifier_str oai:rdu.unc.edu.ar:11086/560965
network_acronym_str RDUUNC
repository_id_str 2572
network_name_str Repositorio Digital Universitario (UNC)
spelling Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?Dadam, FlorenciaRivarola, María AngélicaVivas, LauraCaeiro, Ximena E.Presión arterialRenin angiotensin systemSex chromosome complementSex hormonesFour core genotypes mouse modelFil: Dadam, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.Fil: Rivarola, María Angélica. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.Fil: Vivas, L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Caeiro, Ximena E. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.Evidence demonstrate that the pressor response to AngII infusion is sexually dimorphic under physiological and pathophysiological circumstances. But why do male and female show differences in rennin angiotensin system (RAS) activation and inhibition? Sex steroids can induce organizational (long-lasting or permanent) effect during critical periods of development but can also impart (temporary or reversible) activational effects. Furthermore, males and females also carry different sex chromosome complements (SCC:XY/XX) and thus are influenced throughout life by different genomes. Previous evidence demonstrates a modulatory effect of SCC in RAS receptor expression (brain/renal), as well as in the AngII sexually dimorphic bradycardic barroreflex and hypertensive responses. In the present study we evaluated the involvement of SCC, organizational and activational hormone effect on changes in mean arterial pressure (MAP) in a 10 min AngII infusion protocol.Fil: Dadam, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.Fil: Rivarola, María Angélica. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.Fil: Vivas, L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Caeiro, Ximena E. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.Otras Ciencias Biológicas2020info:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfhttp://hdl.handle.net/11086/560965enginfo:eu-repo/semantics/openAccessreponame:Repositorio Digital Universitario (UNC)instname:Universidad Nacional de Córdobainstacron:UNC2026-04-23T10:35:35Zoai:rdu.unc.edu.ar:11086/560965Institucionalhttps://rdu.unc.edu.ar/Universidad públicaNo correspondehttp://rdu.unc.edu.ar/oai/snrdoca.unc@gmail.comArgentinaNo correspondeNo correspondeNo correspondeopendoar:25722026-04-23 10:35:35.993Repositorio Digital Universitario (UNC) - Universidad Nacional de Córdobafalse
dc.title.none.fl_str_mv Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?
title Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?
spellingShingle Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?
Dadam, Florencia
Presión arterial
Renin angiotensin system
Sex chromosome complement
Sex hormones
Four core genotypes mouse model
title_short Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?
title_full Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?
title_fullStr Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?
title_full_unstemmed Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?
title_sort Sex differences in blood pressure response to continuous ang ii infusion: are sex hormones the only ones to blame for such differences?
dc.creator.none.fl_str_mv Dadam, Florencia
Rivarola, María Angélica
Vivas, Laura
Caeiro, Ximena E.
author Dadam, Florencia
author_facet Dadam, Florencia
Rivarola, María Angélica
Vivas, Laura
Caeiro, Ximena E.
author_role author
author2 Rivarola, María Angélica
Vivas, Laura
Caeiro, Ximena E.
author2_role author
author
author
dc.subject.none.fl_str_mv Presión arterial
Renin angiotensin system
Sex chromosome complement
Sex hormones
Four core genotypes mouse model
topic Presión arterial
Renin angiotensin system
Sex chromosome complement
Sex hormones
Four core genotypes mouse model
dc.description.none.fl_txt_mv Fil: Dadam, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Fil: Rivarola, María Angélica. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Fil: Vivas, L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.
Fil: Caeiro, Ximena E. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Evidence demonstrate that the pressor response to AngII infusion is sexually dimorphic under physiological and pathophysiological circumstances. But why do male and female show differences in rennin angiotensin system (RAS) activation and inhibition? Sex steroids can induce organizational (long-lasting or permanent) effect during critical periods of development but can also impart (temporary or reversible) activational effects. Furthermore, males and females also carry different sex chromosome complements (SCC:XY/XX) and thus are influenced throughout life by different genomes. Previous evidence demonstrates a modulatory effect of SCC in RAS receptor expression (brain/renal), as well as in the AngII sexually dimorphic bradycardic barroreflex and hypertensive responses. In the present study we evaluated the involvement of SCC, organizational and activational hormone effect on changes in mean arterial pressure (MAP) in a 10 min AngII infusion protocol.
Fil: Dadam, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Fil: Rivarola, María Angélica. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Fil: Vivas, L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.
Fil: Caeiro, Ximena E. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
Otras Ciencias Biológicas
description Fil: Dadam, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/conferenceObject
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
format conferenceObject
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11086/560965
url http://hdl.handle.net/11086/560965
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositorio Digital Universitario (UNC)
instname:Universidad Nacional de Córdoba
instacron:UNC
reponame_str Repositorio Digital Universitario (UNC)
collection Repositorio Digital Universitario (UNC)
instname_str Universidad Nacional de Córdoba
instacron_str UNC
institution UNC
repository.name.fl_str_mv Repositorio Digital Universitario (UNC) - Universidad Nacional de Córdoba
repository.mail.fl_str_mv oca.unc@gmail.com
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score 13.05261

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