Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome

Autores
Magaudda, Adriana; Dalla Bernardina, Bernardo; De Marco, Paolo; Sfaello, Zenon Milciades; Longo, Michele; Colamaria, V.; Daniele, O.; Tortorella, G.; Tata, M.A.; Di Pierri, R.; Meduri, M.
Año de publicación
1993
Idioma
español castellano
Tipo de recurso
artículo
Estado
versión aceptada
Descripción
Twenty patients affected by bilateral occipital cortical-subcortical calcification (BOC) are described, 19 (95%) had epilepsy. In 8 of 16 cases studied, intestinal biopsy revealed coeliac disease. Fourteen patients had occipital partial epilepsy with a relatively benign outcome, while 4 patients were affected by a severe form of epilepsy, with very frequent, drug-resistant, generalised and partial seizures with mental deterioration. One patient had a single episode of convulsive status epilepticus at four months of age. The neurological examination was normal in all patients. CT showed flocculo-nodular, cortico-subcortical BOC, without enhancement and without lobar or hemispheric atrophy. MRI was normal. The clinical and neuroimaging features of these patients are different therefore from those with the Sturge-Weber Syndrome. The study confirms a high prevalence of coliac disease in patients with BOC, but the relationship between these two pathologies still needs to be clarified.
Fil: Magaudda, Adriana. University of Messina; Italia
Fil: Dalla Bernardina, Bernardo. University of Verona; Italia
Fil: De Marco, Paolo. Centro Angeli Custodi. Istituti Ospedalieri; Italia
Fil: Sfaello, Zenon Milciades. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Longo, Michele. Università Cattolica del Sacro Cuore; Italia
Fil: Colamaria, V. University of Verona; Italia
Fil: Daniele, O. University of Palermo; Italia
Fil: Tortorella, G. University of Verona; Italia
Fil: Tata, M.A. University of Naples; Italia
Fil: Di Pierri, R. University of Messina; Italia
Fil: Meduri, M. University of Verona; Italia
Fuente
Magaudda, Adriana ORCID: https://orcid.org/0000-0001-9862-8493 , Dalla Bernardina, Bernardo ORCID: https://orcid.org/0000-0002-8740-4686 , De Marco, Paolo ORCID: https://orcid.org/0000-0002-9322-6986 , Sfaello, Zenon Milciades, Longo, Michele ORCID: https://orcid.org/0000-0002-9188-2680 , Colamaria, V., Daniele, O., Tortorella, G., Tata, M.A., Di Pierri, R. and Meduri, M. (1993) Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome. Journal of Neurology. Neurosurgery and Psychiatry, 56 (8). pp. 885-889. ISSN 0022-3050
Materia
R Medicina (General)
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
Repositorio
Producción Académica (UCC)
Institución
Universidad Católica de Córdoba
OAI Identificador
oai:pa.bibdigital.uccor.edu.ar:3711
Acceder
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oai_identifier_str oai:pa.bibdigital.uccor.edu.ar:3711
network_acronym_str PAUCC
repository_id_str 2718
network_name_str Producción Académica (UCC)
spelling Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndromeMagaudda, AdrianaDalla Bernardina, BernardoDe Marco, PaoloSfaello, Zenon MilciadesLongo, MicheleColamaria, V.Daniele, O.Tortorella, G.Tata, M.A.Di Pierri, R.Meduri, M.R Medicina (General)Twenty patients affected by bilateral occipital cortical-subcortical calcification (BOC) are described, 19 (95%) had epilepsy. In 8 of 16 cases studied, intestinal biopsy revealed coeliac disease. Fourteen patients had occipital partial epilepsy with a relatively benign outcome, while 4 patients were affected by a severe form of epilepsy, with very frequent, drug-resistant, generalised and partial seizures with mental deterioration. One patient had a single episode of convulsive status epilepticus at four months of age. The neurological examination was normal in all patients. CT showed flocculo-nodular, cortico-subcortical BOC, without enhancement and without lobar or hemispheric atrophy. MRI was normal. The clinical and neuroimaging features of these patients are different therefore from those with the Sturge-Weber Syndrome. The study confirms a high prevalence of coliac disease in patients with BOC, but the relationship between these two pathologies still needs to be clarified.Fil: Magaudda, Adriana. University of Messina; ItaliaFil: Dalla Bernardina, Bernardo. University of Verona; ItaliaFil: De Marco, Paolo. Centro Angeli Custodi. Istituti Ospedalieri; ItaliaFil: Sfaello, Zenon Milciades. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; ArgentinaFil: Longo, Michele. Università Cattolica del Sacro Cuore; ItaliaFil: Colamaria, V. University of Verona; ItaliaFil: Daniele, O. University of Palermo; ItaliaFil: Tortorella, G. University of Verona; ItaliaFil: Tata, M.A. University of Naples; ItaliaFil: Di Pierri, R. University of Messina; ItaliaFil: Meduri, M. University of Verona; Italia1993-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://pa.bibdigital.ucc.edu.ar/3711/1/A_Magaudda_DallaBernardina_DeMarco_Sfaello_Longo_Colamaria_Daniele_Tortorella_Tata_Pierri_Meduri.pdf Magaudda, Adriana ORCID: https://orcid.org/0000-0001-9862-8493 <https://orcid.org/0000-0001-9862-8493>, Dalla Bernardina, Bernardo ORCID: https://orcid.org/0000-0002-8740-4686 <https://orcid.org/0000-0002-8740-4686>, De Marco, Paolo ORCID: https://orcid.org/0000-0002-9322-6986 <https://orcid.org/0000-0002-9322-6986>, Sfaello, Zenon Milciades, Longo, Michele ORCID: https://orcid.org/0000-0002-9188-2680 <https://orcid.org/0000-0002-9188-2680>, Colamaria, V., Daniele, O., Tortorella, G., Tata, M.A., Di Pierri, R. and Meduri, M. (1993) Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome. Journal of Neurology. Neurosurgery and Psychiatry, 56 (8). pp. 885-889. ISSN 0022-3050 reponame:Producción Académica (UCC)instname:Universidad Católica de Córdobaspahttp://pa.bibdigital.ucc.edu.ar/3711/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es2025-10-23T11:17:56Zoai:pa.bibdigital.uccor.edu.ar:3711instacron:UCCInstitucionalhttp://pa.bibdigital.uccor.edu.ar/Universidad privadaNo correspondehttp://pa.bibdigital.uccor.edu.ar/cgi/oai2bibdir@uccor.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:27182025-10-23 11:17:57.039Producción Académica (UCC) - Universidad Católica de Córdobafalse
dc.title.none.fl_str_mv Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
title Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
spellingShingle Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
Magaudda, Adriana
R Medicina (General)
title_short Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
title_full Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
title_fullStr Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
title_full_unstemmed Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
title_sort Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome
dc.creator.none.fl_str_mv Magaudda, Adriana
Dalla Bernardina, Bernardo
De Marco, Paolo
Sfaello, Zenon Milciades
Longo, Michele
Colamaria, V.
Daniele, O.
Tortorella, G.
Tata, M.A.
Di Pierri, R.
Meduri, M.
author Magaudda, Adriana
author_facet Magaudda, Adriana
Dalla Bernardina, Bernardo
De Marco, Paolo
Sfaello, Zenon Milciades
Longo, Michele
Colamaria, V.
Daniele, O.
Tortorella, G.
Tata, M.A.
Di Pierri, R.
Meduri, M.
author_role author
author2 Dalla Bernardina, Bernardo
De Marco, Paolo
Sfaello, Zenon Milciades
Longo, Michele
Colamaria, V.
Daniele, O.
Tortorella, G.
Tata, M.A.
Di Pierri, R.
Meduri, M.
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv R Medicina (General)
topic R Medicina (General)
dc.description.none.fl_txt_mv Twenty patients affected by bilateral occipital cortical-subcortical calcification (BOC) are described, 19 (95%) had epilepsy. In 8 of 16 cases studied, intestinal biopsy revealed coeliac disease. Fourteen patients had occipital partial epilepsy with a relatively benign outcome, while 4 patients were affected by a severe form of epilepsy, with very frequent, drug-resistant, generalised and partial seizures with mental deterioration. One patient had a single episode of convulsive status epilepticus at four months of age. The neurological examination was normal in all patients. CT showed flocculo-nodular, cortico-subcortical BOC, without enhancement and without lobar or hemispheric atrophy. MRI was normal. The clinical and neuroimaging features of these patients are different therefore from those with the Sturge-Weber Syndrome. The study confirms a high prevalence of coliac disease in patients with BOC, but the relationship between these two pathologies still needs to be clarified.
Fil: Magaudda, Adriana. University of Messina; Italia
Fil: Dalla Bernardina, Bernardo. University of Verona; Italia
Fil: De Marco, Paolo. Centro Angeli Custodi. Istituti Ospedalieri; Italia
Fil: Sfaello, Zenon Milciades. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Longo, Michele. Università Cattolica del Sacro Cuore; Italia
Fil: Colamaria, V. University of Verona; Italia
Fil: Daniele, O. University of Palermo; Italia
Fil: Tortorella, G. University of Verona; Italia
Fil: Tata, M.A. University of Naples; Italia
Fil: Di Pierri, R. University of Messina; Italia
Fil: Meduri, M. University of Verona; Italia
description Twenty patients affected by bilateral occipital cortical-subcortical calcification (BOC) are described, 19 (95%) had epilepsy. In 8 of 16 cases studied, intestinal biopsy revealed coeliac disease. Fourteen patients had occipital partial epilepsy with a relatively benign outcome, while 4 patients were affected by a severe form of epilepsy, with very frequent, drug-resistant, generalised and partial seizures with mental deterioration. One patient had a single episode of convulsive status epilepticus at four months of age. The neurological examination was normal in all patients. CT showed flocculo-nodular, cortico-subcortical BOC, without enhancement and without lobar or hemispheric atrophy. MRI was normal. The clinical and neuroimaging features of these patients are different therefore from those with the Sturge-Weber Syndrome. The study confirms a high prevalence of coliac disease in patients with BOC, but the relationship between these two pathologies still needs to be clarified.
publishDate 1993
dc.date.none.fl_str_mv 1993-12-31
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://pa.bibdigital.ucc.edu.ar/3711/1/A_Magaudda_DallaBernardina_DeMarco_Sfaello_Longo_Colamaria_Daniele_Tortorella_Tata_Pierri_Meduri.pdf
url http://pa.bibdigital.ucc.edu.ar/3711/1/A_Magaudda_DallaBernardina_DeMarco_Sfaello_Longo_Colamaria_Daniele_Tortorella_Tata_Pierri_Meduri.pdf
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv http://pa.bibdigital.ucc.edu.ar/3711/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Magaudda, Adriana ORCID: https://orcid.org/0000-0001-9862-8493 <https://orcid.org/0000-0001-9862-8493>, Dalla Bernardina, Bernardo ORCID: https://orcid.org/0000-0002-8740-4686 <https://orcid.org/0000-0002-8740-4686>, De Marco, Paolo ORCID: https://orcid.org/0000-0002-9322-6986 <https://orcid.org/0000-0002-9322-6986>, Sfaello, Zenon Milciades, Longo, Michele ORCID: https://orcid.org/0000-0002-9188-2680 <https://orcid.org/0000-0002-9188-2680>, Colamaria, V., Daniele, O., Tortorella, G., Tata, M.A., Di Pierri, R. and Meduri, M. (1993) Bilateral occipital calcification, epilepsy and coeliac disease: clinical and neuroimaging features of a new syndrome. Journal of Neurology. Neurosurgery and Psychiatry, 56 (8). pp. 885-889. ISSN 0022-3050
reponame:Producción Académica (UCC)
instname:Universidad Católica de Córdoba
reponame_str Producción Académica (UCC)
collection Producción Académica (UCC)
instname_str Universidad Católica de Córdoba
repository.name.fl_str_mv Producción Académica (UCC) - Universidad Católica de Córdoba
repository.mail.fl_str_mv bibdir@uccor.edu.ar
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score 12.982451

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