Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features
- Autores
- Seifer, Gustavo; Blenkmann, Alejandro; Princich, Juan Pablo; Consalvo, Damián; Papayannis, Cristina; Muravchik, Carlos Horacio; Kochen, Silvia
- Año de publicación
- 2012
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Purpose. The main purpose is to define more accurately the epileptogenic zone (EZ) with noninvasive methods in those patients with MRI diagnosis of focal cortical dysplasia (FCD) and epilepsy who are candidates of epilepsy surgery. Methods. Twenty patients were evaluated prospectively between 2007 and 2010 with comprehensive clinical evaluation, video-electroencephalography, diffusion tensor imaging (DTI), and high-resolution EEG to localize the equivalent current dipole (ECD). Key Findings. In 11 cases with white matter asymmetries in DTI the ECDs were located next to lesion on MRI with mean distance of 14.63 millimeters with topographical correlation with the EZ. Significance. We could establish a hypothesis of EZ based on Video-EEG, high-resolution EEG, ECD method, MRI, and DTI. These results are consistent with the hypothesis that the EZ in the FCD is complex and is often larger than visible lesion in MRI.
Instituto de Investigaciones en Electrónica, Control y Procesamiento de Señales
Comisión de Investigaciones Científicas de la provincia de Buenos Aires - Materia
-
Ingeniería Electrónica
Epilepsia
Neuroimágenes
Imagen por Resonancia Magnética - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by/4.0/
- Repositorio
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/123678
Ver los metadatos del registro completo
id |
SEDICI_aab5b6e82cc9a6bc26476038bdd7f892 |
---|---|
oai_identifier_str |
oai:sedici.unlp.edu.ar:10915/123678 |
network_acronym_str |
SEDICI |
repository_id_str |
1329 |
network_name_str |
SEDICI (UNLP) |
spelling |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging FeaturesSeifer, GustavoBlenkmann, AlejandroPrincich, Juan PabloConsalvo, DamiánPapayannis, CristinaMuravchik, Carlos HoracioKochen, SilviaIngeniería ElectrónicaEpilepsiaNeuroimágenesImagen por Resonancia MagnéticaPurpose. The main purpose is to define more accurately the epileptogenic zone (EZ) with noninvasive methods in those patients with MRI diagnosis of focal cortical dysplasia (FCD) and epilepsy who are candidates of epilepsy surgery. Methods. Twenty patients were evaluated prospectively between 2007 and 2010 with comprehensive clinical evaluation, video-electroencephalography, diffusion tensor imaging (DTI), and high-resolution EEG to localize the equivalent current dipole (ECD). Key Findings. In 11 cases with white matter asymmetries in DTI the ECDs were located next to lesion on MRI with mean distance of 14.63 millimeters with topographical correlation with the EZ. Significance. We could establish a hypothesis of EZ based on Video-EEG, high-resolution EEG, ECD method, MRI, and DTI. These results are consistent with the hypothesis that the EZ in the FCD is complex and is often larger than visible lesion in MRI.Instituto de Investigaciones en Electrónica, Control y Procesamiento de SeñalesComisión de Investigaciones Científicas de la provincia de Buenos Aires2012-03-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/123678enginfo:eu-repo/semantics/altIdentifier/issn/2090-1356info:eu-repo/semantics/altIdentifier/issn/2090-1348info:eu-repo/semantics/altIdentifier/pmid/22957239info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/736784info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:29:33Zoai:sedici.unlp.edu.ar:10915/123678Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:29:33.599SEDICI (UNLP) - Universidad Nacional de La Platafalse |
dc.title.none.fl_str_mv |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features |
title |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features |
spellingShingle |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features Seifer, Gustavo Ingeniería Electrónica Epilepsia Neuroimágenes Imagen por Resonancia Magnética |
title_short |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features |
title_full |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features |
title_fullStr |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features |
title_full_unstemmed |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features |
title_sort |
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features |
dc.creator.none.fl_str_mv |
Seifer, Gustavo Blenkmann, Alejandro Princich, Juan Pablo Consalvo, Damián Papayannis, Cristina Muravchik, Carlos Horacio Kochen, Silvia |
author |
Seifer, Gustavo |
author_facet |
Seifer, Gustavo Blenkmann, Alejandro Princich, Juan Pablo Consalvo, Damián Papayannis, Cristina Muravchik, Carlos Horacio Kochen, Silvia |
author_role |
author |
author2 |
Blenkmann, Alejandro Princich, Juan Pablo Consalvo, Damián Papayannis, Cristina Muravchik, Carlos Horacio Kochen, Silvia |
author2_role |
author author author author author author |
dc.subject.none.fl_str_mv |
Ingeniería Electrónica Epilepsia Neuroimágenes Imagen por Resonancia Magnética |
topic |
Ingeniería Electrónica Epilepsia Neuroimágenes Imagen por Resonancia Magnética |
dc.description.none.fl_txt_mv |
Purpose. The main purpose is to define more accurately the epileptogenic zone (EZ) with noninvasive methods in those patients with MRI diagnosis of focal cortical dysplasia (FCD) and epilepsy who are candidates of epilepsy surgery. Methods. Twenty patients were evaluated prospectively between 2007 and 2010 with comprehensive clinical evaluation, video-electroencephalography, diffusion tensor imaging (DTI), and high-resolution EEG to localize the equivalent current dipole (ECD). Key Findings. In 11 cases with white matter asymmetries in DTI the ECDs were located next to lesion on MRI with mean distance of 14.63 millimeters with topographical correlation with the EZ. Significance. We could establish a hypothesis of EZ based on Video-EEG, high-resolution EEG, ECD method, MRI, and DTI. These results are consistent with the hypothesis that the EZ in the FCD is complex and is often larger than visible lesion in MRI. Instituto de Investigaciones en Electrónica, Control y Procesamiento de Señales Comisión de Investigaciones Científicas de la provincia de Buenos Aires |
description |
Purpose. The main purpose is to define more accurately the epileptogenic zone (EZ) with noninvasive methods in those patients with MRI diagnosis of focal cortical dysplasia (FCD) and epilepsy who are candidates of epilepsy surgery. Methods. Twenty patients were evaluated prospectively between 2007 and 2010 with comprehensive clinical evaluation, video-electroencephalography, diffusion tensor imaging (DTI), and high-resolution EEG to localize the equivalent current dipole (ECD). Key Findings. In 11 cases with white matter asymmetries in DTI the ECDs were located next to lesion on MRI with mean distance of 14.63 millimeters with topographical correlation with the EZ. Significance. We could establish a hypothesis of EZ based on Video-EEG, high-resolution EEG, ECD method, MRI, and DTI. These results are consistent with the hypothesis that the EZ in the FCD is complex and is often larger than visible lesion in MRI. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-03-05 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Articulo http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://sedici.unlp.edu.ar/handle/10915/123678 |
url |
http://sedici.unlp.edu.ar/handle/10915/123678 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/issn/2090-1356 info:eu-repo/semantics/altIdentifier/issn/2090-1348 info:eu-repo/semantics/altIdentifier/pmid/22957239 info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/736784 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:SEDICI (UNLP) instname:Universidad Nacional de La Plata instacron:UNLP |
reponame_str |
SEDICI (UNLP) |
collection |
SEDICI (UNLP) |
instname_str |
Universidad Nacional de La Plata |
instacron_str |
UNLP |
institution |
UNLP |
repository.name.fl_str_mv |
SEDICI (UNLP) - Universidad Nacional de La Plata |
repository.mail.fl_str_mv |
alira@sedici.unlp.edu.ar |
_version_ |
1844616174233452544 |
score |
13.070432 |