Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina

Autores
Marfil, Maria Jimena; Barandiaran, Soledad; Zumarraga, Martin Jose; Germani, Ludmila; Faccini, Tamara; Linares, Marcelo; Capra, Silvana; Gramajo, Laura; Martinez Vivot, Marcela; Falzoni, Elvira
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Mycobacterium bovis and Mycobacterium avium are the most important Mycobacteria isolated from diseased dogs, but Mycobacterium tuberculosis can be isolated as well, especially when close contact with humans exists. Free ranging street dogs may carry zoonotic diseases, being a potential health risk to new owners after adoption. In this study, the clinical case of a dog affected by Mycobacterium tuberculosis is described. A six-year-old bitch that had been living with a homeless man was rescued and put for adoption in dog shelter. After being adopted, her health declined, and abdominal ultrasound and exploratory laparoscopy were performed. A tuberculosis-like lesion in the liver was biopsied and histopathological, bacteriological, and molecular analyses were carried out. Then, the animal was euthanized and necropsied, and disseminated macroscopic tuberculosis-like lesions were observed in abdominal organs. Mycobacterium presence was confirmed by histopathological and bacteriological methods. Genotyping identified a SIT-1228 Mycobacterium tuberculosis strain. Notification to the sanitary authorities was performed and the couple that had contact with the dog were alerted and sent to the hospital for assessment, as Mycobacterium tuberculosis is a primary pathogenic agent for humans. The epidemiology in this clinical case is unclear, but the most likely source of infection might have been consumption of sputum contaminated food during the years that this bitch lived with the homeless man, because this person had died with chronic respiratory symptoms. Veterinarians must consider this disease and perform a complete diagnosis when dogs that used to live on the streets show nonspecific clinical signs.
Instituto de Biotecnología
Fil: Marfil, Maria Jimena. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Barandiaran, Soledad. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Barandiaran, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Zumarraga, Martin Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Germani, Ludmila. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Faccini, Tamara. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Linares, Marcelo. Linares Centro Veterinario; Argentina
Fil: Capra, Silvana. Instituto de Zoonosis Luis Pasteur; Argentina
Fil: Gramajo, Laura. Instituto de Zoonosis Luis Pasteur; Argentina
Fil: Martinez Vivot, Marcela. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Falzoni, Elvira. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fuente
Veterinary Research Communications (Published: 08 February 2022)
Materia
Mycobacterium tuberculosis Infections
Diagnostic Techniques
Genotypes
Dogs
Infeccion mycobacterium tuberculosis
Mycobacterium tuberculosis
Técnicas de Diagnosis
Genotipos
Perro
Argentina
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
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oai_identifier_str oai:localhost:20.500.12123/12514
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network_name_str INTA Digital (INTA)
spelling Mycobacterium tuberculosis infection in a free‑ranging urban dog from ArgentinaMarfil, Maria JimenaBarandiaran, SoledadZumarraga, Martin JoseGermani, LudmilaFaccini, TamaraLinares, MarceloCapra, SilvanaGramajo, LauraMartinez Vivot, MarcelaFalzoni, ElviraMycobacterium tuberculosis InfectionsDiagnostic TechniquesGenotypesDogsInfeccion mycobacterium tuberculosisMycobacterium tuberculosisTécnicas de DiagnosisGenotiposPerroArgentinaMycobacterium bovis and Mycobacterium avium are the most important Mycobacteria isolated from diseased dogs, but Mycobacterium tuberculosis can be isolated as well, especially when close contact with humans exists. Free ranging street dogs may carry zoonotic diseases, being a potential health risk to new owners after adoption. In this study, the clinical case of a dog affected by Mycobacterium tuberculosis is described. A six-year-old bitch that had been living with a homeless man was rescued and put for adoption in dog shelter. After being adopted, her health declined, and abdominal ultrasound and exploratory laparoscopy were performed. A tuberculosis-like lesion in the liver was biopsied and histopathological, bacteriological, and molecular analyses were carried out. Then, the animal was euthanized and necropsied, and disseminated macroscopic tuberculosis-like lesions were observed in abdominal organs. Mycobacterium presence was confirmed by histopathological and bacteriological methods. Genotyping identified a SIT-1228 Mycobacterium tuberculosis strain. Notification to the sanitary authorities was performed and the couple that had contact with the dog were alerted and sent to the hospital for assessment, as Mycobacterium tuberculosis is a primary pathogenic agent for humans. The epidemiology in this clinical case is unclear, but the most likely source of infection might have been consumption of sputum contaminated food during the years that this bitch lived with the homeless man, because this person had died with chronic respiratory symptoms. Veterinarians must consider this disease and perform a complete diagnosis when dogs that used to live on the streets show nonspecific clinical signs.Instituto de BiotecnologíaFil: Marfil, Maria Jimena. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; ArgentinaFil: Barandiaran, Soledad. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; ArgentinaFil: Barandiaran, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Zumarraga, Martin Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Germani, Ludmila. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; ArgentinaFil: Faccini, Tamara. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; ArgentinaFil: Linares, Marcelo. Linares Centro Veterinario; ArgentinaFil: Capra, Silvana. Instituto de Zoonosis Luis Pasteur; ArgentinaFil: Gramajo, Laura. Instituto de Zoonosis Luis Pasteur; ArgentinaFil: Martinez Vivot, Marcela. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; ArgentinaFil: Falzoni, Elvira. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; ArgentinaSpringer2022-08-08T10:11:01Z2022-08-08T10:11:01Z2022-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/12514https://link.springer.com/article/10.1007/s11259-022-09898-41573-7446https://doi.org/10.1007/s11259-022-09898-4Veterinary Research Communications (Published: 08 February 2022)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/2019-PD-E5-I103-001/2019-PD-E5-I103-001/AR./Desarrollo de tecnologías diagnósticas y estudios epidemiológicos para el control de enfermedades que afectan la producción animal y la salud públicainfo:eu-repo/semantics/restrictedAccess2025-09-04T09:49:30Zoai:localhost:20.500.12123/12514instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:49:31.116INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina
title Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina
spellingShingle Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina
Marfil, Maria Jimena
Mycobacterium tuberculosis Infections
Diagnostic Techniques
Genotypes
Dogs
Infeccion mycobacterium tuberculosis
Mycobacterium tuberculosis
Técnicas de Diagnosis
Genotipos
Perro
Argentina
title_short Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina
title_full Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina
title_fullStr Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina
title_full_unstemmed Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina
title_sort Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina
dc.creator.none.fl_str_mv Marfil, Maria Jimena
Barandiaran, Soledad
Zumarraga, Martin Jose
Germani, Ludmila
Faccini, Tamara
Linares, Marcelo
Capra, Silvana
Gramajo, Laura
Martinez Vivot, Marcela
Falzoni, Elvira
author Marfil, Maria Jimena
author_facet Marfil, Maria Jimena
Barandiaran, Soledad
Zumarraga, Martin Jose
Germani, Ludmila
Faccini, Tamara
Linares, Marcelo
Capra, Silvana
Gramajo, Laura
Martinez Vivot, Marcela
Falzoni, Elvira
author_role author
author2 Barandiaran, Soledad
Zumarraga, Martin Jose
Germani, Ludmila
Faccini, Tamara
Linares, Marcelo
Capra, Silvana
Gramajo, Laura
Martinez Vivot, Marcela
Falzoni, Elvira
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Mycobacterium tuberculosis Infections
Diagnostic Techniques
Genotypes
Dogs
Infeccion mycobacterium tuberculosis
Mycobacterium tuberculosis
Técnicas de Diagnosis
Genotipos
Perro
Argentina
topic Mycobacterium tuberculosis Infections
Diagnostic Techniques
Genotypes
Dogs
Infeccion mycobacterium tuberculosis
Mycobacterium tuberculosis
Técnicas de Diagnosis
Genotipos
Perro
Argentina
dc.description.none.fl_txt_mv Mycobacterium bovis and Mycobacterium avium are the most important Mycobacteria isolated from diseased dogs, but Mycobacterium tuberculosis can be isolated as well, especially when close contact with humans exists. Free ranging street dogs may carry zoonotic diseases, being a potential health risk to new owners after adoption. In this study, the clinical case of a dog affected by Mycobacterium tuberculosis is described. A six-year-old bitch that had been living with a homeless man was rescued and put for adoption in dog shelter. After being adopted, her health declined, and abdominal ultrasound and exploratory laparoscopy were performed. A tuberculosis-like lesion in the liver was biopsied and histopathological, bacteriological, and molecular analyses were carried out. Then, the animal was euthanized and necropsied, and disseminated macroscopic tuberculosis-like lesions were observed in abdominal organs. Mycobacterium presence was confirmed by histopathological and bacteriological methods. Genotyping identified a SIT-1228 Mycobacterium tuberculosis strain. Notification to the sanitary authorities was performed and the couple that had contact with the dog were alerted and sent to the hospital for assessment, as Mycobacterium tuberculosis is a primary pathogenic agent for humans. The epidemiology in this clinical case is unclear, but the most likely source of infection might have been consumption of sputum contaminated food during the years that this bitch lived with the homeless man, because this person had died with chronic respiratory symptoms. Veterinarians must consider this disease and perform a complete diagnosis when dogs that used to live on the streets show nonspecific clinical signs.
Instituto de Biotecnología
Fil: Marfil, Maria Jimena. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Barandiaran, Soledad. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Barandiaran, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Zumarraga, Martin Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Germani, Ludmila. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Faccini, Tamara. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Linares, Marcelo. Linares Centro Veterinario; Argentina
Fil: Capra, Silvana. Instituto de Zoonosis Luis Pasteur; Argentina
Fil: Gramajo, Laura. Instituto de Zoonosis Luis Pasteur; Argentina
Fil: Martinez Vivot, Marcela. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
Fil: Falzoni, Elvira. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentina
description Mycobacterium bovis and Mycobacterium avium are the most important Mycobacteria isolated from diseased dogs, but Mycobacterium tuberculosis can be isolated as well, especially when close contact with humans exists. Free ranging street dogs may carry zoonotic diseases, being a potential health risk to new owners after adoption. In this study, the clinical case of a dog affected by Mycobacterium tuberculosis is described. A six-year-old bitch that had been living with a homeless man was rescued and put for adoption in dog shelter. After being adopted, her health declined, and abdominal ultrasound and exploratory laparoscopy were performed. A tuberculosis-like lesion in the liver was biopsied and histopathological, bacteriological, and molecular analyses were carried out. Then, the animal was euthanized and necropsied, and disseminated macroscopic tuberculosis-like lesions were observed in abdominal organs. Mycobacterium presence was confirmed by histopathological and bacteriological methods. Genotyping identified a SIT-1228 Mycobacterium tuberculosis strain. Notification to the sanitary authorities was performed and the couple that had contact with the dog were alerted and sent to the hospital for assessment, as Mycobacterium tuberculosis is a primary pathogenic agent for humans. The epidemiology in this clinical case is unclear, but the most likely source of infection might have been consumption of sputum contaminated food during the years that this bitch lived with the homeless man, because this person had died with chronic respiratory symptoms. Veterinarians must consider this disease and perform a complete diagnosis when dogs that used to live on the streets show nonspecific clinical signs.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-08T10:11:01Z
2022-08-08T10:11:01Z
2022-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/12514
https://link.springer.com/article/10.1007/s11259-022-09898-4
1573-7446
https://doi.org/10.1007/s11259-022-09898-4
url http://hdl.handle.net/20.500.12123/12514
https://link.springer.com/article/10.1007/s11259-022-09898-4
https://doi.org/10.1007/s11259-022-09898-4
identifier_str_mv 1573-7446
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/2019-PD-E5-I103-001/2019-PD-E5-I103-001/AR./Desarrollo de tecnologías diagnósticas y estudios epidemiológicos para el control de enfermedades que afectan la producción animal y la salud pública
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv Veterinary Research Communications (Published: 08 February 2022)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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