Research gaps and new insights in the evolution of Drosophila seminal fluid proteins

Autores
Hurtado, Juan; Almeida, Francisca Cunha; Belliard, Silvina Ahnahi; Revale, Santiago; Hasson, Esteban
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión aceptada
Descripción
While the striking effects of seminal fluid proteins (SFPs) on females are fairly conserved among Diptera, most SFPs lack detectable homologues among the SFP repertoires of phylogenetically distant species. How such a rapidly changing proteome conserves functions across taxa is a fascinating question. However, this and other pivotal aspects of SFPs' evolution remain elusive because discoveries on these proteins have been mainly restricted to the model Drosophila melanogaster. Here, we provide an overview of the current knowledge on the inter-specific divergence of the SFP repertoire in Drosophila and compile the increasing amount of relevant genomic information from multiple species. Capitalizing on the accumulated knowledge in D. melanogaster, we present novel sets of high-confidence SFP candidates and transcription factors presumptively involved in regulating the expression of SFPs. We also address open questions by performing comparative genomic analyses that failed to support the existence of many conserved SFPs shared by most dipterans and indicated that gene co-option is the most frequent mechanism accounting for the origin of Drosophila SFP-coding genes. We hope our update establishes a starting point to integrate further data and thus widen the understanding of the intricate evolution of these proteins.
Instituto de Genética
Fil: Hurtado, Juan. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina
Fil: Hurtado, Juan. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Almeida, Francisca Cunha. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina
Fil: Almeida, Francisca Cunha. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Belliard, Silvina A. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética. Laboratorio de Genética de Insectos de Importancia Económica; Argentina
Fil: Belliard, Silvina A. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Belliard, Silvina A. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Revale, Santiago. University of Oxford. Wellcome Trust Centre for Human Genetics; Reino Unido
Fil: Hasson, Esteban. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina
Fil: Hasson, Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fuente
Insect Molecular Biology (First published: 07 November 2021)
Materia
Drosophila
Drosophila melanogaster
Genética
Proteínas
Genetics
Proteins
Genes
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/10875
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spelling Research gaps and new insights in the evolution of Drosophila seminal fluid proteinsHurtado, JuanAlmeida, Francisca CunhaBelliard, Silvina AhnahiRevale, SantiagoHasson, EstebanDrosophilaDrosophila melanogasterGenéticaProteínasGeneticsProteinsGenesWhile the striking effects of seminal fluid proteins (SFPs) on females are fairly conserved among Diptera, most SFPs lack detectable homologues among the SFP repertoires of phylogenetically distant species. How such a rapidly changing proteome conserves functions across taxa is a fascinating question. However, this and other pivotal aspects of SFPs' evolution remain elusive because discoveries on these proteins have been mainly restricted to the model Drosophila melanogaster. Here, we provide an overview of the current knowledge on the inter-specific divergence of the SFP repertoire in Drosophila and compile the increasing amount of relevant genomic information from multiple species. Capitalizing on the accumulated knowledge in D. melanogaster, we present novel sets of high-confidence SFP candidates and transcription factors presumptively involved in regulating the expression of SFPs. We also address open questions by performing comparative genomic analyses that failed to support the existence of many conserved SFPs shared by most dipterans and indicated that gene co-option is the most frequent mechanism accounting for the origin of Drosophila SFP-coding genes. We hope our update establishes a starting point to integrate further data and thus widen the understanding of the intricate evolution of these proteins.Instituto de GenéticaFil: Hurtado, Juan. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; ArgentinaFil: Hurtado, Juan. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Almeida, Francisca Cunha. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; ArgentinaFil: Almeida, Francisca Cunha. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Belliard, Silvina A. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética. Laboratorio de Genética de Insectos de Importancia Económica; ArgentinaFil: Belliard, Silvina A. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Belliard, Silvina A. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Revale, Santiago. University of Oxford. Wellcome Trust Centre for Human Genetics; Reino UnidoFil: Hasson, Esteban. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; ArgentinaFil: Hasson, Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaWileyinfo:eu-repo/date/embargoEnd/2022-12-092021-12-09T16:42:11Z2021-12-09T16:42:11Z2021-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/10875https://onlinelibrary.wiley.com/doi/abs/10.1111/imb.127460962-10751365-2583https://doi.org/10.1111/imb.12746Insect Molecular Biology (First published: 07 November 2021)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-09-29T13:45:25Zoai:localhost:20.500.12123/10875instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:45:26.071INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Research gaps and new insights in the evolution of Drosophila seminal fluid proteins
title Research gaps and new insights in the evolution of Drosophila seminal fluid proteins
spellingShingle Research gaps and new insights in the evolution of Drosophila seminal fluid proteins
Hurtado, Juan
Drosophila
Drosophila melanogaster
Genética
Proteínas
Genetics
Proteins
Genes
title_short Research gaps and new insights in the evolution of Drosophila seminal fluid proteins
title_full Research gaps and new insights in the evolution of Drosophila seminal fluid proteins
title_fullStr Research gaps and new insights in the evolution of Drosophila seminal fluid proteins
title_full_unstemmed Research gaps and new insights in the evolution of Drosophila seminal fluid proteins
title_sort Research gaps and new insights in the evolution of Drosophila seminal fluid proteins
dc.creator.none.fl_str_mv Hurtado, Juan
Almeida, Francisca Cunha
Belliard, Silvina Ahnahi
Revale, Santiago
Hasson, Esteban
author Hurtado, Juan
author_facet Hurtado, Juan
Almeida, Francisca Cunha
Belliard, Silvina Ahnahi
Revale, Santiago
Hasson, Esteban
author_role author
author2 Almeida, Francisca Cunha
Belliard, Silvina Ahnahi
Revale, Santiago
Hasson, Esteban
author2_role author
author
author
author
dc.subject.none.fl_str_mv Drosophila
Drosophila melanogaster
Genética
Proteínas
Genetics
Proteins
Genes
topic Drosophila
Drosophila melanogaster
Genética
Proteínas
Genetics
Proteins
Genes
dc.description.none.fl_txt_mv While the striking effects of seminal fluid proteins (SFPs) on females are fairly conserved among Diptera, most SFPs lack detectable homologues among the SFP repertoires of phylogenetically distant species. How such a rapidly changing proteome conserves functions across taxa is a fascinating question. However, this and other pivotal aspects of SFPs' evolution remain elusive because discoveries on these proteins have been mainly restricted to the model Drosophila melanogaster. Here, we provide an overview of the current knowledge on the inter-specific divergence of the SFP repertoire in Drosophila and compile the increasing amount of relevant genomic information from multiple species. Capitalizing on the accumulated knowledge in D. melanogaster, we present novel sets of high-confidence SFP candidates and transcription factors presumptively involved in regulating the expression of SFPs. We also address open questions by performing comparative genomic analyses that failed to support the existence of many conserved SFPs shared by most dipterans and indicated that gene co-option is the most frequent mechanism accounting for the origin of Drosophila SFP-coding genes. We hope our update establishes a starting point to integrate further data and thus widen the understanding of the intricate evolution of these proteins.
Instituto de Genética
Fil: Hurtado, Juan. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina
Fil: Hurtado, Juan. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Almeida, Francisca Cunha. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina
Fil: Almeida, Francisca Cunha. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Belliard, Silvina A. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética. Laboratorio de Genética de Insectos de Importancia Económica; Argentina
Fil: Belliard, Silvina A. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Belliard, Silvina A. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Revale, Santiago. University of Oxford. Wellcome Trust Centre for Human Genetics; Reino Unido
Fil: Hasson, Esteban. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina
Fil: Hasson, Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
description While the striking effects of seminal fluid proteins (SFPs) on females are fairly conserved among Diptera, most SFPs lack detectable homologues among the SFP repertoires of phylogenetically distant species. How such a rapidly changing proteome conserves functions across taxa is a fascinating question. However, this and other pivotal aspects of SFPs' evolution remain elusive because discoveries on these proteins have been mainly restricted to the model Drosophila melanogaster. Here, we provide an overview of the current knowledge on the inter-specific divergence of the SFP repertoire in Drosophila and compile the increasing amount of relevant genomic information from multiple species. Capitalizing on the accumulated knowledge in D. melanogaster, we present novel sets of high-confidence SFP candidates and transcription factors presumptively involved in regulating the expression of SFPs. We also address open questions by performing comparative genomic analyses that failed to support the existence of many conserved SFPs shared by most dipterans and indicated that gene co-option is the most frequent mechanism accounting for the origin of Drosophila SFP-coding genes. We hope our update establishes a starting point to integrate further data and thus widen the understanding of the intricate evolution of these proteins.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-09T16:42:11Z
2021-12-09T16:42:11Z
2021-11
info:eu-repo/date/embargoEnd/2022-12-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/10875
https://onlinelibrary.wiley.com/doi/abs/10.1111/imb.12746
0962-1075
1365-2583
https://doi.org/10.1111/imb.12746
url http://hdl.handle.net/20.500.12123/10875
https://onlinelibrary.wiley.com/doi/abs/10.1111/imb.12746
https://doi.org/10.1111/imb.12746
identifier_str_mv 0962-1075
1365-2583
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv Insect Molecular Biology (First published: 07 November 2021)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.559606

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