Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties

Autores
Juarez, Andrea Virginia; Yudi, Lidia Mabel; Alvarez Igarzabal, Cecilia Ines; Strumia, Miriam Cristina
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The transfers of tetraethylammonium (TEA+) and protonated triflupromazine (HTFP+) through a hydrogel/liquid interface (g/o) and a liquid/liquid interface (w/o) were compared using cyclic voltammetry. After the two phases were put in contact, the behavior of each molecule was analyzed at different pH values and at different time points. The gel induces hydrophobic and electrostatic interactions with TEA+ and HTFP+, shifting the peak potentials to more positive values. The diffusion coefficients, D, in both phases (g and w) at different pH values were calculated. In the case of TEA+, the D value remains constant in both systems. However, the D value of HTFP+ is lower in the gel phase than in the liquid phase. HTFP+ is transferred from the aqueous phase to the organic phase via a direct mechanism that involves coupled acid?base and partition processes. At the g/o interface, the coupled chemical reactions of HTFP+ were inhibited by the drug/gel interaction. The results demonstrate that the g/o system could be used as a model to study the controlled release of charged drugs. 
Fil: Juarez, Andrea Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; Argentina; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Yudi, Lidia Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; Argentina; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Alvarez Igarzabal, Cecilia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina; Argentina. Universidad Nacional de Córdoba; Argentina
Materia
Gel-Liquid Interface
Hydrogel
Ities
Ion Transfer
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/14733
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/14733
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base propertiesJuarez, Andrea VirginiaYudi, Lidia MabelAlvarez Igarzabal, Cecilia InesStrumia, Miriam CristinaGel-Liquid InterfaceHydrogelItiesIon Transferhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The transfers of tetraethylammonium (TEA+) and protonated triflupromazine (HTFP+) through a hydrogel/liquid interface (g/o) and a liquid/liquid interface (w/o) were compared using cyclic voltammetry. After the two phases were put in contact, the behavior of each molecule was analyzed at different pH values and at different time points. The gel induces hydrophobic and electrostatic interactions with TEA+ and HTFP+, shifting the peak potentials to more positive values. The diffusion coefficients, D, in both phases (g and w) at different pH values were calculated. In the case of TEA+, the D value remains constant in both systems. However, the D value of HTFP+ is lower in the gel phase than in the liquid phase. HTFP+ is transferred from the aqueous phase to the organic phase via a direct mechanism that involves coupled acid?base and partition processes. At the g/o interface, the coupled chemical reactions of HTFP+ were inhibited by the drug/gel interaction. The results demonstrate that the g/o system could be used as a model to study the controlled release of charged drugs. Fil: Juarez, Andrea Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; Argentina; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Yudi, Lidia Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; Argentina; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Alvarez Igarzabal, Cecilia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina; Argentina. Universidad Nacional de Córdoba; ArgentinaElsevier2010-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/14733Juarez, Andrea Virginia; Yudi, Lidia Mabel; Alvarez Igarzabal, Cecilia Ines; Strumia, Miriam Cristina; Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties; Elsevier; Electrochimica Acta; 55; 7; 2-2010; 2409-24130013-4686enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0013468609014571info:eu-repo/semantics/altIdentifier/doi/10.1016/j.electacta.2009.11.077info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:18:51Zoai:ri.conicet.gov.ar:11336/14733instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:18:51.654CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties
title Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties
spellingShingle Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties
Juarez, Andrea Virginia
Gel-Liquid Interface
Hydrogel
Ities
Ion Transfer
title_short Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties
title_full Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties
title_fullStr Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties
title_full_unstemmed Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties
title_sort Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties
dc.creator.none.fl_str_mv Juarez, Andrea Virginia
Yudi, Lidia Mabel
Alvarez Igarzabal, Cecilia Ines
Strumia, Miriam Cristina
author Juarez, Andrea Virginia
author_facet Juarez, Andrea Virginia
Yudi, Lidia Mabel
Alvarez Igarzabal, Cecilia Ines
Strumia, Miriam Cristina
author_role author
author2 Yudi, Lidia Mabel
Alvarez Igarzabal, Cecilia Ines
Strumia, Miriam Cristina
author2_role author
author
author
dc.subject.none.fl_str_mv Gel-Liquid Interface
Hydrogel
Ities
Ion Transfer
topic Gel-Liquid Interface
Hydrogel
Ities
Ion Transfer
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The transfers of tetraethylammonium (TEA+) and protonated triflupromazine (HTFP+) through a hydrogel/liquid interface (g/o) and a liquid/liquid interface (w/o) were compared using cyclic voltammetry. After the two phases were put in contact, the behavior of each molecule was analyzed at different pH values and at different time points. The gel induces hydrophobic and electrostatic interactions with TEA+ and HTFP+, shifting the peak potentials to more positive values. The diffusion coefficients, D, in both phases (g and w) at different pH values were calculated. In the case of TEA+, the D value remains constant in both systems. However, the D value of HTFP+ is lower in the gel phase than in the liquid phase. HTFP+ is transferred from the aqueous phase to the organic phase via a direct mechanism that involves coupled acid?base and partition processes. At the g/o interface, the coupled chemical reactions of HTFP+ were inhibited by the drug/gel interaction. The results demonstrate that the g/o system could be used as a model to study the controlled release of charged drugs. 
Fil: Juarez, Andrea Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; Argentina; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Yudi, Lidia Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Investigaciones En Físicoquímica de Córdoba; Argentina; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Alvarez Igarzabal, Cecilia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina; Argentina. Universidad Nacional de Córdoba; Argentina
description The transfers of tetraethylammonium (TEA+) and protonated triflupromazine (HTFP+) through a hydrogel/liquid interface (g/o) and a liquid/liquid interface (w/o) were compared using cyclic voltammetry. After the two phases were put in contact, the behavior of each molecule was analyzed at different pH values and at different time points. The gel induces hydrophobic and electrostatic interactions with TEA+ and HTFP+, shifting the peak potentials to more positive values. The diffusion coefficients, D, in both phases (g and w) at different pH values were calculated. In the case of TEA+, the D value remains constant in both systems. However, the D value of HTFP+ is lower in the gel phase than in the liquid phase. HTFP+ is transferred from the aqueous phase to the organic phase via a direct mechanism that involves coupled acid?base and partition processes. At the g/o interface, the coupled chemical reactions of HTFP+ were inhibited by the drug/gel interaction. The results demonstrate that the g/o system could be used as a model to study the controlled release of charged drugs. 
publishDate 2010
dc.date.none.fl_str_mv 2010-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/14733
Juarez, Andrea Virginia; Yudi, Lidia Mabel; Alvarez Igarzabal, Cecilia Ines; Strumia, Miriam Cristina; Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties; Elsevier; Electrochimica Acta; 55; 7; 2-2010; 2409-2413
0013-4686
url http://hdl.handle.net/11336/14733
identifier_str_mv Juarez, Andrea Virginia; Yudi, Lidia Mabel; Alvarez Igarzabal, Cecilia Ines; Strumia, Miriam Cristina; Cation transfer across a hydrogel/organic phase: Effect of cation size, hydrophobicity and acid–base properties; Elsevier; Electrochimica Acta; 55; 7; 2-2010; 2409-2413
0013-4686
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0013468609014571
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.electacta.2009.11.077
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614155032592384
score 13.070432

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