NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster

Autores
Sabio, Germán; Quesada Allue, Luis Alberto; Pérez, Martín Mariano
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Drosophila melanogaster genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.
Fil: Sabio, Germán. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
Fil: Quesada Allue, Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
Fil: Pérez, Martín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
Materia
Catecholamines
Neurotransmitters
Insect Brain
Insect Epidermis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/12695
Acceder
id CONICETDig_fa7e44fa8f1622fbb587d2dc83de5e1f
oai_identifier_str oai:ri.conicet.gov.ar:11336/12695
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling NBAD-hydrolase processing in brain and epidermis of Drosophila melanogasterSabio, GermánQuesada Allue, Luis AlbertoPérez, Martín MarianoCatecholaminesNeurotransmittersInsect BrainInsect Epidermishttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Drosophila melanogaster genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.Fil: Sabio, Germán. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; ArgentinaFil: Quesada Allue, Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; ArgentinaFil: Pérez, Martín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; ArgentinaUniversity of Oklahoma2011-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/12695Sabio, Germán; Quesada Allue, Luis Alberto; Pérez, Martín Mariano; NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster; University of Oklahoma; Drosophila Information Service; 94; 3-2011; 100-1040070-7333enginfo:eu-repo/semantics/altIdentifier/url/http://www.ou.edu/journals/dis/DIS94/Sabio%20100.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:34:27Zoai:ri.conicet.gov.ar:11336/12695instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:34:27.779CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
title NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
spellingShingle NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
Sabio, Germán
Catecholamines
Neurotransmitters
Insect Brain
Insect Epidermis
title_short NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
title_full NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
title_fullStr NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
title_full_unstemmed NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
title_sort NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster
dc.creator.none.fl_str_mv Sabio, Germán
Quesada Allue, Luis Alberto
Pérez, Martín Mariano
author Sabio, Germán
author_facet Sabio, Germán
Quesada Allue, Luis Alberto
Pérez, Martín Mariano
author_role author
author2 Quesada Allue, Luis Alberto
Pérez, Martín Mariano
author2_role author
author
dc.subject.none.fl_str_mv Catecholamines
Neurotransmitters
Insect Brain
Insect Epidermis
topic Catecholamines
Neurotransmitters
Insect Brain
Insect Epidermis
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Drosophila melanogaster genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.
Fil: Sabio, Germán. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
Fil: Quesada Allue, Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
Fil: Pérez, Martín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquimicas de Buenos Aires; Argentina. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
description Drosophila melanogaster genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.genes ebony and tan are responsible for the synthesis and hydrolysis of N-â-alanylderivatives of biogenic amines, such as N-â-alanyldopamine (NBAD) and N-â- alanylhistamine (carcinine). These are pleiotropic genes expressed in epidermis and nervous tissue. Neurotransmitter levels are altered in ebony and tan; both mutants have reduced levels of histamine. However, ebony shows an increased level of dopamine, whereas tan shows reduced levels of this catecholamine. Biogenic amines are important in reproduction. Mutants that have low levels of neurotransmitters show impaired reproduction or conditional viability. In the present report we analyzed the fertility and viability of e1 and t1 in order to elucidate if the altered levels of neurotransmitters have a consequence in the reproduction of these mutants.
publishDate 2011
dc.date.none.fl_str_mv 2011-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/12695
Sabio, Germán; Quesada Allue, Luis Alberto; Pérez, Martín Mariano; NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster; University of Oklahoma; Drosophila Information Service; 94; 3-2011; 100-104
0070-7333
url http://hdl.handle.net/11336/12695
identifier_str_mv Sabio, Germán; Quesada Allue, Luis Alberto; Pérez, Martín Mariano; NBAD-hydrolase processing in brain and epidermis of Drosophila melanogaster; University of Oklahoma; Drosophila Information Service; 94; 3-2011; 100-104
0070-7333
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ou.edu/journals/dis/DIS94/Sabio%20100.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv University of Oklahoma
publisher.none.fl_str_mv University of Oklahoma
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083473205362688
score 13.22299

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