Understanding and exploiting late blight resistance in the age of effectors

Autores
Vleeshouwers, Vivianne G. A. A.; Raffaele, Sylvain; Vossen, Jack H.; Champouret, Nicolas; Oliva, Ricardo; Segretin, Maria Eugenia; Rietman, Hendrik; Cano, Liliana M.; Lokossou, Anoma; Kessel, Geert; Pel, Mathieu A.; Kamoun, Sophien
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Potato (Solanum tuberosum) is the world's third-largest food crop. It severely suffers from late blight, a devastating disease caused by Phytophthora infestans. This oomycete pathogen secretes host-translocated RXLR effectors that include avirulence (AVR) proteins, which are targeted by resistance (R) proteins from wild Solanum species. Most Solanum R genes appear to have coevolved with P. infestans at its center of origin in central Mexico. Various R and Avr genes were recently cloned, and here we catalog characterized R-AVR pairs. We describe the mechanisms that P. infestans employs for evading R protein recognition and discuss partial resistance and partial virulence phenotypes in the context of our knowledge of effector diversity and activity. Genome-wide catalogs of P. infestans effectors are available, enabling effectoromics approaches that accelerate R gene cloning and specificity profiling. Engineering R genes with expanded pathogen recognition has also become possible. Importantly, monitoring effector allelic diversity in pathogen populations can assist in R gene deployment in agriculture.
Fil: Vleeshouwers, Vivianne G. A. A.. Wageningen UR Plant Breeding; Países Bajos
Fil: Raffaele, Sylvain. Norwich Research Park; Reino Unido
Fil: Vossen, Jack H.. Wageningen UR Plant Breeding; Países Bajos
Fil: Champouret, Nicolas. Wageningen UR Plant Breeding; Países Bajos
Fil: Oliva, Ricardo. Norwich Research Park; Reino Unido
Fil: Segretin, Maria Eugenia. Norwich Research Park; Reino Unido. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina
Fil: Rietman, Hendrik. Wageningen UR Plant Breeding; Países Bajos
Fil: Cano, Liliana M.. Norwich Research Park; Reino Unido
Fil: Lokossou, Anoma. Wageningen UR Plant Breeding; Países Bajos
Fil: Kessel, Geert. Plant Research International; Reino Unido
Fil: Pel, Mathieu A.. Wageningen UR Plant Breeding; Países Bajos
Fil: Kamoun, Sophien. Norwich Research Park; Reino Unido
Materia
Avirulence
Disease Resistance Genes
Effectors
Oomycetes
Phytophthora Infestans
Potato
Solanum
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/79598
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/79598
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Understanding and exploiting late blight resistance in the age of effectorsVleeshouwers, Vivianne G. A. A.Raffaele, SylvainVossen, Jack H.Champouret, NicolasOliva, RicardoSegretin, Maria EugeniaRietman, HendrikCano, Liliana M.Lokossou, AnomaKessel, GeertPel, Mathieu A.Kamoun, SophienAvirulenceDisease Resistance GenesEffectorsOomycetesPhytophthora InfestansPotatoSolanumhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Potato (Solanum tuberosum) is the world's third-largest food crop. It severely suffers from late blight, a devastating disease caused by Phytophthora infestans. This oomycete pathogen secretes host-translocated RXLR effectors that include avirulence (AVR) proteins, which are targeted by resistance (R) proteins from wild Solanum species. Most Solanum R genes appear to have coevolved with P. infestans at its center of origin in central Mexico. Various R and Avr genes were recently cloned, and here we catalog characterized R-AVR pairs. We describe the mechanisms that P. infestans employs for evading R protein recognition and discuss partial resistance and partial virulence phenotypes in the context of our knowledge of effector diversity and activity. Genome-wide catalogs of P. infestans effectors are available, enabling effectoromics approaches that accelerate R gene cloning and specificity profiling. Engineering R genes with expanded pathogen recognition has also become possible. Importantly, monitoring effector allelic diversity in pathogen populations can assist in R gene deployment in agriculture.Fil: Vleeshouwers, Vivianne G. A. A.. Wageningen UR Plant Breeding; Países BajosFil: Raffaele, Sylvain. Norwich Research Park; Reino UnidoFil: Vossen, Jack H.. Wageningen UR Plant Breeding; Países BajosFil: Champouret, Nicolas. Wageningen UR Plant Breeding; Países BajosFil: Oliva, Ricardo. Norwich Research Park; Reino UnidoFil: Segretin, Maria Eugenia. Norwich Research Park; Reino Unido. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Rietman, Hendrik. Wageningen UR Plant Breeding; Países BajosFil: Cano, Liliana M.. Norwich Research Park; Reino UnidoFil: Lokossou, Anoma. Wageningen UR Plant Breeding; Países BajosFil: Kessel, Geert. Plant Research International; Reino UnidoFil: Pel, Mathieu A.. Wageningen UR Plant Breeding; Países BajosFil: Kamoun, Sophien. Norwich Research Park; Reino UnidoAnnual Reviews2011-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/79598Vleeshouwers, Vivianne G. A. A.; Raffaele, Sylvain; Vossen, Jack H.; Champouret, Nicolas; Oliva, Ricardo; et al.; Understanding and exploiting late blight resistance in the age of effectors; Annual Reviews; Annual Review Of Phytopathology; 49; 9-2011; 507-5310066-4286CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1146/annurev-phyto-072910-095326info:eu-repo/semantics/altIdentifier/url/https://www.annualreviews.org/doi/10.1146/annurev-phyto-072910-095326info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:59:06Zoai:ri.conicet.gov.ar:11336/79598instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:59:06.784CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Understanding and exploiting late blight resistance in the age of effectors
title Understanding and exploiting late blight resistance in the age of effectors
spellingShingle Understanding and exploiting late blight resistance in the age of effectors
Vleeshouwers, Vivianne G. A. A.
Avirulence
Disease Resistance Genes
Effectors
Oomycetes
Phytophthora Infestans
Potato
Solanum
title_short Understanding and exploiting late blight resistance in the age of effectors
title_full Understanding and exploiting late blight resistance in the age of effectors
title_fullStr Understanding and exploiting late blight resistance in the age of effectors
title_full_unstemmed Understanding and exploiting late blight resistance in the age of effectors
title_sort Understanding and exploiting late blight resistance in the age of effectors
dc.creator.none.fl_str_mv Vleeshouwers, Vivianne G. A. A.
Raffaele, Sylvain
Vossen, Jack H.
Champouret, Nicolas
Oliva, Ricardo
Segretin, Maria Eugenia
Rietman, Hendrik
Cano, Liliana M.
Lokossou, Anoma
Kessel, Geert
Pel, Mathieu A.
Kamoun, Sophien
author Vleeshouwers, Vivianne G. A. A.
author_facet Vleeshouwers, Vivianne G. A. A.
Raffaele, Sylvain
Vossen, Jack H.
Champouret, Nicolas
Oliva, Ricardo
Segretin, Maria Eugenia
Rietman, Hendrik
Cano, Liliana M.
Lokossou, Anoma
Kessel, Geert
Pel, Mathieu A.
Kamoun, Sophien
author_role author
author2 Raffaele, Sylvain
Vossen, Jack H.
Champouret, Nicolas
Oliva, Ricardo
Segretin, Maria Eugenia
Rietman, Hendrik
Cano, Liliana M.
Lokossou, Anoma
Kessel, Geert
Pel, Mathieu A.
Kamoun, Sophien
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Avirulence
Disease Resistance Genes
Effectors
Oomycetes
Phytophthora Infestans
Potato
Solanum
topic Avirulence
Disease Resistance Genes
Effectors
Oomycetes
Phytophthora Infestans
Potato
Solanum
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Potato (Solanum tuberosum) is the world's third-largest food crop. It severely suffers from late blight, a devastating disease caused by Phytophthora infestans. This oomycete pathogen secretes host-translocated RXLR effectors that include avirulence (AVR) proteins, which are targeted by resistance (R) proteins from wild Solanum species. Most Solanum R genes appear to have coevolved with P. infestans at its center of origin in central Mexico. Various R and Avr genes were recently cloned, and here we catalog characterized R-AVR pairs. We describe the mechanisms that P. infestans employs for evading R protein recognition and discuss partial resistance and partial virulence phenotypes in the context of our knowledge of effector diversity and activity. Genome-wide catalogs of P. infestans effectors are available, enabling effectoromics approaches that accelerate R gene cloning and specificity profiling. Engineering R genes with expanded pathogen recognition has also become possible. Importantly, monitoring effector allelic diversity in pathogen populations can assist in R gene deployment in agriculture.
Fil: Vleeshouwers, Vivianne G. A. A.. Wageningen UR Plant Breeding; Países Bajos
Fil: Raffaele, Sylvain. Norwich Research Park; Reino Unido
Fil: Vossen, Jack H.. Wageningen UR Plant Breeding; Países Bajos
Fil: Champouret, Nicolas. Wageningen UR Plant Breeding; Países Bajos
Fil: Oliva, Ricardo. Norwich Research Park; Reino Unido
Fil: Segretin, Maria Eugenia. Norwich Research Park; Reino Unido. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina
Fil: Rietman, Hendrik. Wageningen UR Plant Breeding; Países Bajos
Fil: Cano, Liliana M.. Norwich Research Park; Reino Unido
Fil: Lokossou, Anoma. Wageningen UR Plant Breeding; Países Bajos
Fil: Kessel, Geert. Plant Research International; Reino Unido
Fil: Pel, Mathieu A.. Wageningen UR Plant Breeding; Países Bajos
Fil: Kamoun, Sophien. Norwich Research Park; Reino Unido
description Potato (Solanum tuberosum) is the world's third-largest food crop. It severely suffers from late blight, a devastating disease caused by Phytophthora infestans. This oomycete pathogen secretes host-translocated RXLR effectors that include avirulence (AVR) proteins, which are targeted by resistance (R) proteins from wild Solanum species. Most Solanum R genes appear to have coevolved with P. infestans at its center of origin in central Mexico. Various R and Avr genes were recently cloned, and here we catalog characterized R-AVR pairs. We describe the mechanisms that P. infestans employs for evading R protein recognition and discuss partial resistance and partial virulence phenotypes in the context of our knowledge of effector diversity and activity. Genome-wide catalogs of P. infestans effectors are available, enabling effectoromics approaches that accelerate R gene cloning and specificity profiling. Engineering R genes with expanded pathogen recognition has also become possible. Importantly, monitoring effector allelic diversity in pathogen populations can assist in R gene deployment in agriculture.
publishDate 2011
dc.date.none.fl_str_mv 2011-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/79598
Vleeshouwers, Vivianne G. A. A.; Raffaele, Sylvain; Vossen, Jack H.; Champouret, Nicolas; Oliva, Ricardo; et al.; Understanding and exploiting late blight resistance in the age of effectors; Annual Reviews; Annual Review Of Phytopathology; 49; 9-2011; 507-531
0066-4286
CONICET Digital
CONICET
url http://hdl.handle.net/11336/79598
identifier_str_mv Vleeshouwers, Vivianne G. A. A.; Raffaele, Sylvain; Vossen, Jack H.; Champouret, Nicolas; Oliva, Ricardo; et al.; Understanding and exploiting late blight resistance in the age of effectors; Annual Reviews; Annual Review Of Phytopathology; 49; 9-2011; 507-531
0066-4286
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1146/annurev-phyto-072910-095326
info:eu-repo/semantics/altIdentifier/url/https://www.annualreviews.org/doi/10.1146/annurev-phyto-072910-095326
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Annual Reviews
publisher.none.fl_str_mv Annual Reviews
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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