Ancient human genomes suggest three ancestral populations for present-day Europeans

Autores
Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; Bailliet, Graciela; Bravi, Claudio Marcelo; Corach, Daniel; Thomas, Mark G.; Ruiz Linares, Andres; Tishkoff, Sarah A.; Singh, Lalji; Thangaraj, Kumarasamy; Villems, Richard; Comas, David; Rem Sukernik; Metspalu, Mait; Meyer, Matthias; Eichler, Evan E.; Burger, Joachim; Slatkin, Montgomery; Pääbo, Svante; Kelso, Janet; Reich, David; Krause, Johannes
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes1,2,3,4 with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians3, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations’ deep relationships and show that early European farmers had ∼44% ancestry from a ‘basal Eurasian’ population that split before the diversification of other non-African lineages.
Fil: Lazaridis, Iosif. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados Unidos
Fil: Patterson, Nick. Massachusetts Institute of Technology; Estados Unidos
Fil: Mittnik, Alissa. University of Tübingen; Alemania
Fil: Renaud, Gabriel. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Mallick, Swapan. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados Unidos
Fil: Bailliet, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Thomas, Mark G.. University College London; Estados Unidos
Fil: Ruiz Linares, Andres. University College London; Estados Unidos
Fil: Tishkoff, Sarah A.. University of Pennsylvania; Estados Unidos
Fil: Singh, Lalji. Council of Scientific & Industrial Research. Centre for Cellular and Molecular Biology; India
Fil: Thangaraj, Kumarasamy. Council of Scientific & Industrial Research. Centre for Cellular and Molecular Biology; India
Fil: Villems, Richard. Evolutionary Biology group. Estonian Biocentre; Estonia. University Of Tartu.; Estonia. Estonian Academy of Sciences; Estonia
Fil: Comas, David. Consejo Superior de Investigaciones Científicas; España. Universitat Pompeu Fabra; España
Fil: Rem Sukernik. Russian Academy of Science. Institute of Molecular and Cellular Biology. Laboratory of Human Molecular Genetics; Rusia
Fil: Metspalu, Mait. Evolutionary Biology group. Estonian Biocentre; Estonia
Fil: Meyer, Matthias. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Eichler, Evan E.. University of Washington; Estados Unidos
Fil: Burger, Joachim. Johannes Gutenberg University Mainz. Institute of Anthropology; Alemania
Fil: Slatkin, Montgomery. University of California at Berkeley; Estados Unidos
Fil: Pääbo, Svante. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Kelso, Janet. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Reich, David. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados Unidos
Fil: Krause, Johannes. University of Tübingen; Alemania
Materia
Ancient Dna
Genomics
Human Origins
Europe
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/30563
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Ancient human genomes suggest three ancestral populations for present-day EuropeansLazaridis, IosifPatterson, NickMittnik, AlissaRenaud, GabrielMallick, SwapanBailliet, GracielaBravi, Claudio MarceloCorach, DanielThomas, Mark G.Ruiz Linares, AndresTishkoff, Sarah A.Singh, LaljiThangaraj, KumarasamyVillems, RichardComas, DavidRem SukernikMetspalu, MaitMeyer, MatthiasEichler, Evan E.Burger, JoachimSlatkin, MontgomeryPääbo, SvanteKelso, JanetReich, DavidKrause, JohannesAncient DnaGenomicsHuman OriginsEuropehttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes1,2,3,4 with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians3, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations’ deep relationships and show that early European farmers had ∼44% ancestry from a ‘basal Eurasian’ population that split before the diversification of other non-African lineages.Fil: Lazaridis, Iosif. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados UnidosFil: Patterson, Nick. Massachusetts Institute of Technology; Estados UnidosFil: Mittnik, Alissa. University of Tübingen; AlemaniaFil: Renaud, Gabriel. Institut Max Planck for Evolutionary Anthropology; AlemaniaFil: Mallick, Swapan. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados UnidosFil: Bailliet, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Thomas, Mark G.. University College London; Estados UnidosFil: Ruiz Linares, Andres. University College London; Estados UnidosFil: Tishkoff, Sarah A.. University of Pennsylvania; Estados UnidosFil: Singh, Lalji. Council of Scientific & Industrial Research. Centre for Cellular and Molecular Biology; IndiaFil: Thangaraj, Kumarasamy. Council of Scientific & Industrial Research. Centre for Cellular and Molecular Biology; IndiaFil: Villems, Richard. Evolutionary Biology group. Estonian Biocentre; Estonia. University Of Tartu.; Estonia. Estonian Academy of Sciences; EstoniaFil: Comas, David. Consejo Superior de Investigaciones Científicas; España. Universitat Pompeu Fabra; EspañaFil: Rem Sukernik. Russian Academy of Science. Institute of Molecular and Cellular Biology. Laboratory of Human Molecular Genetics; RusiaFil: Metspalu, Mait. Evolutionary Biology group. Estonian Biocentre; EstoniaFil: Meyer, Matthias. Institut Max Planck for Evolutionary Anthropology; AlemaniaFil: Eichler, Evan E.. University of Washington; Estados UnidosFil: Burger, Joachim. Johannes Gutenberg University Mainz. Institute of Anthropology; AlemaniaFil: Slatkin, Montgomery. University of California at Berkeley; Estados UnidosFil: Pääbo, Svante. Institut Max Planck for Evolutionary Anthropology; AlemaniaFil: Kelso, Janet. Institut Max Planck for Evolutionary Anthropology; AlemaniaFil: Reich, David. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados UnidosFil: Krause, Johannes. University of Tübingen; AlemaniaNature Publishing Group2014-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/30563Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; et al.; Ancient human genomes suggest three ancestral populations for present-day Europeans; Nature Publishing Group; Nature; 513; 9-2014; 409-4130028-08361476-4687CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/nature13673info:eu-repo/semantics/altIdentifier/doi/10.1038/nature13673info:eu-repo/semantics/altIdentifier/url/https://arxiv.org/abs/1312.6639info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:06:34Zoai:ri.conicet.gov.ar:11336/30563instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:06:34.529CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Ancient human genomes suggest three ancestral populations for present-day Europeans
title Ancient human genomes suggest three ancestral populations for present-day Europeans
spellingShingle Ancient human genomes suggest three ancestral populations for present-day Europeans
Lazaridis, Iosif
Ancient Dna
Genomics
Human Origins
Europe
title_short Ancient human genomes suggest three ancestral populations for present-day Europeans
title_full Ancient human genomes suggest three ancestral populations for present-day Europeans
title_fullStr Ancient human genomes suggest three ancestral populations for present-day Europeans
title_full_unstemmed Ancient human genomes suggest three ancestral populations for present-day Europeans
title_sort Ancient human genomes suggest three ancestral populations for present-day Europeans
dc.creator.none.fl_str_mv Lazaridis, Iosif
Patterson, Nick
Mittnik, Alissa
Renaud, Gabriel
Mallick, Swapan
Bailliet, Graciela
Bravi, Claudio Marcelo
Corach, Daniel
Thomas, Mark G.
Ruiz Linares, Andres
Tishkoff, Sarah A.
Singh, Lalji
Thangaraj, Kumarasamy
Villems, Richard
Comas, David
Rem Sukernik
Metspalu, Mait
Meyer, Matthias
Eichler, Evan E.
Burger, Joachim
Slatkin, Montgomery
Pääbo, Svante
Kelso, Janet
Reich, David
Krause, Johannes
author Lazaridis, Iosif
author_facet Lazaridis, Iosif
Patterson, Nick
Mittnik, Alissa
Renaud, Gabriel
Mallick, Swapan
Bailliet, Graciela
Bravi, Claudio Marcelo
Corach, Daniel
Thomas, Mark G.
Ruiz Linares, Andres
Tishkoff, Sarah A.
Singh, Lalji
Thangaraj, Kumarasamy
Villems, Richard
Comas, David
Rem Sukernik
Metspalu, Mait
Meyer, Matthias
Eichler, Evan E.
Burger, Joachim
Slatkin, Montgomery
Pääbo, Svante
Kelso, Janet
Reich, David
Krause, Johannes
author_role author
author2 Patterson, Nick
Mittnik, Alissa
Renaud, Gabriel
Mallick, Swapan
Bailliet, Graciela
Bravi, Claudio Marcelo
Corach, Daniel
Thomas, Mark G.
Ruiz Linares, Andres
Tishkoff, Sarah A.
Singh, Lalji
Thangaraj, Kumarasamy
Villems, Richard
Comas, David
Rem Sukernik
Metspalu, Mait
Meyer, Matthias
Eichler, Evan E.
Burger, Joachim
Slatkin, Montgomery
Pääbo, Svante
Kelso, Janet
Reich, David
Krause, Johannes
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Ancient Dna
Genomics
Human Origins
Europe
topic Ancient Dna
Genomics
Human Origins
Europe
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes1,2,3,4 with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians3, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations’ deep relationships and show that early European farmers had ∼44% ancestry from a ‘basal Eurasian’ population that split before the diversification of other non-African lineages.
Fil: Lazaridis, Iosif. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados Unidos
Fil: Patterson, Nick. Massachusetts Institute of Technology; Estados Unidos
Fil: Mittnik, Alissa. University of Tübingen; Alemania
Fil: Renaud, Gabriel. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Mallick, Swapan. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados Unidos
Fil: Bailliet, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Thomas, Mark G.. University College London; Estados Unidos
Fil: Ruiz Linares, Andres. University College London; Estados Unidos
Fil: Tishkoff, Sarah A.. University of Pennsylvania; Estados Unidos
Fil: Singh, Lalji. Council of Scientific & Industrial Research. Centre for Cellular and Molecular Biology; India
Fil: Thangaraj, Kumarasamy. Council of Scientific & Industrial Research. Centre for Cellular and Molecular Biology; India
Fil: Villems, Richard. Evolutionary Biology group. Estonian Biocentre; Estonia. University Of Tartu.; Estonia. Estonian Academy of Sciences; Estonia
Fil: Comas, David. Consejo Superior de Investigaciones Científicas; España. Universitat Pompeu Fabra; España
Fil: Rem Sukernik. Russian Academy of Science. Institute of Molecular and Cellular Biology. Laboratory of Human Molecular Genetics; Rusia
Fil: Metspalu, Mait. Evolutionary Biology group. Estonian Biocentre; Estonia
Fil: Meyer, Matthias. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Eichler, Evan E.. University of Washington; Estados Unidos
Fil: Burger, Joachim. Johannes Gutenberg University Mainz. Institute of Anthropology; Alemania
Fil: Slatkin, Montgomery. University of California at Berkeley; Estados Unidos
Fil: Pääbo, Svante. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Kelso, Janet. Institut Max Planck for Evolutionary Anthropology; Alemania
Fil: Reich, David. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados Unidos
Fil: Krause, Johannes. University of Tübingen; Alemania
description We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes1,2,3,4 with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians3, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations’ deep relationships and show that early European farmers had ∼44% ancestry from a ‘basal Eurasian’ population that split before the diversification of other non-African lineages.
publishDate 2014
dc.date.none.fl_str_mv 2014-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/30563
Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; et al.; Ancient human genomes suggest three ancestral populations for present-day Europeans; Nature Publishing Group; Nature; 513; 9-2014; 409-413
0028-0836
1476-4687
CONICET Digital
CONICET
url http://hdl.handle.net/11336/30563
identifier_str_mv Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; et al.; Ancient human genomes suggest three ancestral populations for present-day Europeans; Nature Publishing Group; Nature; 513; 9-2014; 409-413
0028-0836
1476-4687
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/doi/10.1038/nature13673
info:eu-repo/semantics/altIdentifier/url/https://arxiv.org/abs/1312.6639
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
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dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
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reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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