Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms

Autores
Fañani, Agustina Belen; Arcos Álvarez, Belén; Banegas, Bárbara Pamela; Rocha, Luciana; Monge Corredor, Julia; Rubio, Ramón G.; Guzmán, Eduardo; Lucia, Alejandro
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The ternary system water/eugenol/poloxamer 407 can form a variety of phases that are strongly influenced by the mixture composition and the thermal history of the system. In this study, we investigated the stabilization of emulsion and gel-like systems in which eugenol is encapsulated in a poloxamer 407 matrix. Our results reveal the complex interplay between poloxamer 407 and eugenol compositions in the stabilization single-phase systems at 25ºC. Increasing concentrations of poloxamer were found to incorporate higher amounts of eugenol into emulsion-like dispersions, effectively preventing coalescence and Ostwald ripening. However, high concentrations of poloxamer 407 induced gelation of these dispersions, resulting in eugenol-loaded poloxamer 407 gels. The thermal annealing of the emulsions at 65◦C for 1 h followed by equilibration at room temperature allows the extension of the compositional range for the formation of homogeneous single-phase systems providing a strategy to modulate the phase diagram of the ternary system. Additionally, the encapsulation of hydrophobic pesticides in gel-like matrices was investigated, showing uniform distribution and consistent loading capacity (approximately 0.70 % w/w) across different pesticides which may contribute to facilitate the environmental distribution and efficacy of the encapsulated molecules. This research highlights the potential of eugenol/ poloxamer 407-based systems as an environmentally friendly platform for the encapsulation and delivery of hydrophobic active molecules, offering a versatile solution for various applications.
Fil: Fañani, Agustina Belen. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; Argentina
Fil: Arcos Álvarez, Belén. Universidad Complutense de Madrid; España
Fil: Banegas, Bárbara Pamela. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; Argentina
Fil: Rocha, Luciana. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; Argentina
Fil: Monge Corredor, Julia. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; España
Fil: Rubio, Ramón G.. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; España
Fil: Guzmán, Eduardo. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; España
Fil: Lucia, Alejandro. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina
Materia
DISPERSIONS
INSECTICIDE
NANOCARRIERS
PEST CONTROL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/265964
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platformsFañani, Agustina BelenArcos Álvarez, BelénBanegas, Bárbara PamelaRocha, LucianaMonge Corredor, JuliaRubio, Ramón G.Guzmán, EduardoLucia, AlejandroDISPERSIONSINSECTICIDENANOCARRIERSPEST CONTROLhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The ternary system water/eugenol/poloxamer 407 can form a variety of phases that are strongly influenced by the mixture composition and the thermal history of the system. In this study, we investigated the stabilization of emulsion and gel-like systems in which eugenol is encapsulated in a poloxamer 407 matrix. Our results reveal the complex interplay between poloxamer 407 and eugenol compositions in the stabilization single-phase systems at 25ºC. Increasing concentrations of poloxamer were found to incorporate higher amounts of eugenol into emulsion-like dispersions, effectively preventing coalescence and Ostwald ripening. However, high concentrations of poloxamer 407 induced gelation of these dispersions, resulting in eugenol-loaded poloxamer 407 gels. The thermal annealing of the emulsions at 65◦C for 1 h followed by equilibration at room temperature allows the extension of the compositional range for the formation of homogeneous single-phase systems providing a strategy to modulate the phase diagram of the ternary system. Additionally, the encapsulation of hydrophobic pesticides in gel-like matrices was investigated, showing uniform distribution and consistent loading capacity (approximately 0.70 % w/w) across different pesticides which may contribute to facilitate the environmental distribution and efficacy of the encapsulated molecules. This research highlights the potential of eugenol/ poloxamer 407-based systems as an environmentally friendly platform for the encapsulation and delivery of hydrophobic active molecules, offering a versatile solution for various applications.Fil: Fañani, Agustina Belen. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; ArgentinaFil: Arcos Álvarez, Belén. Universidad Complutense de Madrid; EspañaFil: Banegas, Bárbara Pamela. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; ArgentinaFil: Rocha, Luciana. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; ArgentinaFil: Monge Corredor, Julia. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; EspañaFil: Rubio, Ramón G.. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; EspañaFil: Guzmán, Eduardo. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; EspañaFil: Lucia, Alejandro. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; ArgentinaElsevier Science2024-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/265964Fañani, Agustina Belen; Arcos Álvarez, Belén; Banegas, Bárbara Pamela; Rocha, Luciana; Monge Corredor, Julia; et al.; Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms; Elsevier Science; Colloids and Surfaces A: Physicochemical and Engineering Aspects; 704; 10-2024; 1-130927-7757CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0927775724023380info:eu-repo/semantics/altIdentifier/doi/10.1016/j.colsurfa.2024.135474info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:48:54Zoai:ri.conicet.gov.ar:11336/265964instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:48:54.96CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms
title Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms
spellingShingle Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms
Fañani, Agustina Belen
DISPERSIONS
INSECTICIDE
NANOCARRIERS
PEST CONTROL
title_short Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms
title_full Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms
title_fullStr Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms
title_full_unstemmed Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms
title_sort Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms
dc.creator.none.fl_str_mv Fañani, Agustina Belen
Arcos Álvarez, Belén
Banegas, Bárbara Pamela
Rocha, Luciana
Monge Corredor, Julia
Rubio, Ramón G.
Guzmán, Eduardo
Lucia, Alejandro
author Fañani, Agustina Belen
author_facet Fañani, Agustina Belen
Arcos Álvarez, Belén
Banegas, Bárbara Pamela
Rocha, Luciana
Monge Corredor, Julia
Rubio, Ramón G.
Guzmán, Eduardo
Lucia, Alejandro
author_role author
author2 Arcos Álvarez, Belén
Banegas, Bárbara Pamela
Rocha, Luciana
Monge Corredor, Julia
Rubio, Ramón G.
Guzmán, Eduardo
Lucia, Alejandro
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv DISPERSIONS
INSECTICIDE
NANOCARRIERS
PEST CONTROL
topic DISPERSIONS
INSECTICIDE
NANOCARRIERS
PEST CONTROL
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The ternary system water/eugenol/poloxamer 407 can form a variety of phases that are strongly influenced by the mixture composition and the thermal history of the system. In this study, we investigated the stabilization of emulsion and gel-like systems in which eugenol is encapsulated in a poloxamer 407 matrix. Our results reveal the complex interplay between poloxamer 407 and eugenol compositions in the stabilization single-phase systems at 25ºC. Increasing concentrations of poloxamer were found to incorporate higher amounts of eugenol into emulsion-like dispersions, effectively preventing coalescence and Ostwald ripening. However, high concentrations of poloxamer 407 induced gelation of these dispersions, resulting in eugenol-loaded poloxamer 407 gels. The thermal annealing of the emulsions at 65◦C for 1 h followed by equilibration at room temperature allows the extension of the compositional range for the formation of homogeneous single-phase systems providing a strategy to modulate the phase diagram of the ternary system. Additionally, the encapsulation of hydrophobic pesticides in gel-like matrices was investigated, showing uniform distribution and consistent loading capacity (approximately 0.70 % w/w) across different pesticides which may contribute to facilitate the environmental distribution and efficacy of the encapsulated molecules. This research highlights the potential of eugenol/ poloxamer 407-based systems as an environmentally friendly platform for the encapsulation and delivery of hydrophobic active molecules, offering a versatile solution for various applications.
Fil: Fañani, Agustina Belen. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; Argentina
Fil: Arcos Álvarez, Belén. Universidad Complutense de Madrid; España
Fil: Banegas, Bárbara Pamela. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; Argentina
Fil: Rocha, Luciana. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; Argentina
Fil: Monge Corredor, Julia. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; España
Fil: Rubio, Ramón G.. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; España
Fil: Guzmán, Eduardo. Universidad Complutense de Madrid. Facultad de Ciencias Químicas; España
Fil: Lucia, Alejandro. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina
description The ternary system water/eugenol/poloxamer 407 can form a variety of phases that are strongly influenced by the mixture composition and the thermal history of the system. In this study, we investigated the stabilization of emulsion and gel-like systems in which eugenol is encapsulated in a poloxamer 407 matrix. Our results reveal the complex interplay between poloxamer 407 and eugenol compositions in the stabilization single-phase systems at 25ºC. Increasing concentrations of poloxamer were found to incorporate higher amounts of eugenol into emulsion-like dispersions, effectively preventing coalescence and Ostwald ripening. However, high concentrations of poloxamer 407 induced gelation of these dispersions, resulting in eugenol-loaded poloxamer 407 gels. The thermal annealing of the emulsions at 65◦C for 1 h followed by equilibration at room temperature allows the extension of the compositional range for the formation of homogeneous single-phase systems providing a strategy to modulate the phase diagram of the ternary system. Additionally, the encapsulation of hydrophobic pesticides in gel-like matrices was investigated, showing uniform distribution and consistent loading capacity (approximately 0.70 % w/w) across different pesticides which may contribute to facilitate the environmental distribution and efficacy of the encapsulated molecules. This research highlights the potential of eugenol/ poloxamer 407-based systems as an environmentally friendly platform for the encapsulation and delivery of hydrophobic active molecules, offering a versatile solution for various applications.
publishDate 2024
dc.date.none.fl_str_mv 2024-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/265964
Fañani, Agustina Belen; Arcos Álvarez, Belén; Banegas, Bárbara Pamela; Rocha, Luciana; Monge Corredor, Julia; et al.; Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms; Elsevier Science; Colloids and Surfaces A: Physicochemical and Engineering Aspects; 704; 10-2024; 1-13
0927-7757
CONICET Digital
CONICET
url http://hdl.handle.net/11336/265964
identifier_str_mv Fañani, Agustina Belen; Arcos Álvarez, Belén; Banegas, Bárbara Pamela; Rocha, Luciana; Monge Corredor, Julia; et al.; Stabilization of gels and emulsions in the ternary water/eugenol/poloxamer 407-system: Physicochemical characterization and potential application as encapsulation platforms; Elsevier Science; Colloids and Surfaces A: Physicochemical and Engineering Aspects; 704; 10-2024; 1-13
0927-7757
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0927775724023380
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.colsurfa.2024.135474
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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