Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")

Autores
Soriano, M, D. P. C.; Quispe, C.; Jiménez Aspee, F.; Theoduloz, C.; Alberto, Maria Rosa; Costamagna, Milena Soledad; Isla, Maria Ines; Schmeda Hirschmann, Guillermo
Año de publicación
2014
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Geoffroea decorticans (Gill. ex Hook. et Arn.) is a native tree, popularly known as “Chañar” growing from I to IV regions of Chile. The distribution range of the species comprises the Chaco phytogeographic zone of South America, including Argentina, western Paraguay and Bolivia. The sweet and pleasant tasting fruits are much appreciated and are commonly used for both culinary and medicinal purposes. The fruits are consumed in different forms (chicha, arrope, hydroalcoholic beverage and jam). Arrope is very similar to honey or plant molasses and it is used instead.1,2 The aim of the current work was to assess the antioxidant and anti-inflammatory activities of chañar fruits and to compare the HPLC pattern of the Amberlite-retained methanolic extracts (ARME) from different Chilean collections of fruits. An arrope sample was included for comparison. The samples comprised different collection places from the Copiapo and Limari valleys associated with precolumbian cultures. Large differences were found in the HPLC patterns of phenolics, allowing a differentiation of fruit samples. The antioxidant activity was measured by scavenging of the DPPH free radical and by ferric reducing antioxidant power (FRAP). The anti-inflammatory activity was assessed by the inhibition of the proinflammatory enzymes lipoxigenase (LOX), ciclooxigenases 1 and 2 (COX-1 and COX-2). At 50 µg/mL, all ARME inhibited the LOX from the beginning of the incubation, with inhibition values between 17.3 and 82.6%. Large differences were found for the activity towards COX-1 and COX-2 with values of 0-80.8% for COX-2 and 0-93.3% for COX-1. The COX-1 was not inhibited by the fruits collected in Alto del Carmen and Camino a El Tránsito. This finding is relevant considering the side effects like gastrointestinal toxicity, derived from COX-1 inhibition.
Fil: Soriano, M, D. P. C.. Universidad de Talca; Chile
Fil: Quispe, C.. Universidad de Talca; Chile
Fil: Jiménez Aspee, F.. Universidad de Talca; Chile
Fil: Theoduloz, C.. Universidad de Talca; Chile
Fil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Costamagna, Milena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Schmeda Hirschmann, Guillermo. Universidad de Talca; Chile
14th International Congress of Ethnopharmacology; VIII Simposio Internacional de Química de Productos Naturales y sus Aplicaciones
Pucon
Chile
Universidad de Talca
Materia
Geoffroea decoticans Chile
Antioxidative
Antiinflammatory
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/235337
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/235337
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")Soriano, M, D. P. C.Quispe, C.Jiménez Aspee, F.Theoduloz, C.Alberto, Maria RosaCostamagna, Milena SoledadIsla, Maria InesSchmeda Hirschmann, GuillermoGeoffroea decoticans ChileAntioxidativeAntiinflammatoryhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Geoffroea decorticans (Gill. ex Hook. et Arn.) is a native tree, popularly known as “Chañar” growing from I to IV regions of Chile. The distribution range of the species comprises the Chaco phytogeographic zone of South America, including Argentina, western Paraguay and Bolivia. The sweet and pleasant tasting fruits are much appreciated and are commonly used for both culinary and medicinal purposes. The fruits are consumed in different forms (chicha, arrope, hydroalcoholic beverage and jam). Arrope is very similar to honey or plant molasses and it is used instead.1,2 The aim of the current work was to assess the antioxidant and anti-inflammatory activities of chañar fruits and to compare the HPLC pattern of the Amberlite-retained methanolic extracts (ARME) from different Chilean collections of fruits. An arrope sample was included for comparison. The samples comprised different collection places from the Copiapo and Limari valleys associated with precolumbian cultures. Large differences were found in the HPLC patterns of phenolics, allowing a differentiation of fruit samples. The antioxidant activity was measured by scavenging of the DPPH free radical and by ferric reducing antioxidant power (FRAP). The anti-inflammatory activity was assessed by the inhibition of the proinflammatory enzymes lipoxigenase (LOX), ciclooxigenases 1 and 2 (COX-1 and COX-2). At 50 µg/mL, all ARME inhibited the LOX from the beginning of the incubation, with inhibition values between 17.3 and 82.6%. Large differences were found for the activity towards COX-1 and COX-2 with values of 0-80.8% for COX-2 and 0-93.3% for COX-1. The COX-1 was not inhibited by the fruits collected in Alto del Carmen and Camino a El Tránsito. This finding is relevant considering the side effects like gastrointestinal toxicity, derived from COX-1 inhibition.Fil: Soriano, M, D. P. C.. Universidad de Talca; ChileFil: Quispe, C.. Universidad de Talca; ChileFil: Jiménez Aspee, F.. Universidad de Talca; ChileFil: Theoduloz, C.. Universidad de Talca; ChileFil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; ArgentinaFil: Costamagna, Milena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; ArgentinaFil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; ArgentinaFil: Schmeda Hirschmann, Guillermo. Universidad de Talca; Chile14th International Congress of Ethnopharmacology; VIII Simposio Internacional de Química de Productos Naturales y sus AplicacionesPuconChileUniversidad de TalcaUniversidad Talca2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/235337Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar"); 14th International Congress of Ethnopharmacology; VIII Simposio Internacional de Química de Productos Naturales y sus Aplicaciones; Pucon; Chile; 2014; 150-150CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://bib.irb.hr/datoteka/742320.Book_of_Abstracts.pdfInternacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:57:10Zoai:ri.conicet.gov.ar:11336/235337instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:57:10.65CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")
title Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")
spellingShingle Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")
Soriano, M, D. P. C.
Geoffroea decoticans Chile
Antioxidative
Antiinflammatory
title_short Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")
title_full Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")
title_fullStr Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")
title_full_unstemmed Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")
title_sort Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar")
dc.creator.none.fl_str_mv Soriano, M, D. P. C.
Quispe, C.
Jiménez Aspee, F.
Theoduloz, C.
Alberto, Maria Rosa
Costamagna, Milena Soledad
Isla, Maria Ines
Schmeda Hirschmann, Guillermo
author Soriano, M, D. P. C.
author_facet Soriano, M, D. P. C.
Quispe, C.
Jiménez Aspee, F.
Theoduloz, C.
Alberto, Maria Rosa
Costamagna, Milena Soledad
Isla, Maria Ines
Schmeda Hirschmann, Guillermo
author_role author
author2 Quispe, C.
Jiménez Aspee, F.
Theoduloz, C.
Alberto, Maria Rosa
Costamagna, Milena Soledad
Isla, Maria Ines
Schmeda Hirschmann, Guillermo
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Geoffroea decoticans Chile
Antioxidative
Antiinflammatory
topic Geoffroea decoticans Chile
Antioxidative
Antiinflammatory
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Geoffroea decorticans (Gill. ex Hook. et Arn.) is a native tree, popularly known as “Chañar” growing from I to IV regions of Chile. The distribution range of the species comprises the Chaco phytogeographic zone of South America, including Argentina, western Paraguay and Bolivia. The sweet and pleasant tasting fruits are much appreciated and are commonly used for both culinary and medicinal purposes. The fruits are consumed in different forms (chicha, arrope, hydroalcoholic beverage and jam). Arrope is very similar to honey or plant molasses and it is used instead.1,2 The aim of the current work was to assess the antioxidant and anti-inflammatory activities of chañar fruits and to compare the HPLC pattern of the Amberlite-retained methanolic extracts (ARME) from different Chilean collections of fruits. An arrope sample was included for comparison. The samples comprised different collection places from the Copiapo and Limari valleys associated with precolumbian cultures. Large differences were found in the HPLC patterns of phenolics, allowing a differentiation of fruit samples. The antioxidant activity was measured by scavenging of the DPPH free radical and by ferric reducing antioxidant power (FRAP). The anti-inflammatory activity was assessed by the inhibition of the proinflammatory enzymes lipoxigenase (LOX), ciclooxigenases 1 and 2 (COX-1 and COX-2). At 50 µg/mL, all ARME inhibited the LOX from the beginning of the incubation, with inhibition values between 17.3 and 82.6%. Large differences were found for the activity towards COX-1 and COX-2 with values of 0-80.8% for COX-2 and 0-93.3% for COX-1. The COX-1 was not inhibited by the fruits collected in Alto del Carmen and Camino a El Tránsito. This finding is relevant considering the side effects like gastrointestinal toxicity, derived from COX-1 inhibition.
Fil: Soriano, M, D. P. C.. Universidad de Talca; Chile
Fil: Quispe, C.. Universidad de Talca; Chile
Fil: Jiménez Aspee, F.. Universidad de Talca; Chile
Fil: Theoduloz, C.. Universidad de Talca; Chile
Fil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Costamagna, Milena Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Schmeda Hirschmann, Guillermo. Universidad de Talca; Chile
14th International Congress of Ethnopharmacology; VIII Simposio Internacional de Química de Productos Naturales y sus Aplicaciones
Pucon
Chile
Universidad de Talca
description Geoffroea decorticans (Gill. ex Hook. et Arn.) is a native tree, popularly known as “Chañar” growing from I to IV regions of Chile. The distribution range of the species comprises the Chaco phytogeographic zone of South America, including Argentina, western Paraguay and Bolivia. The sweet and pleasant tasting fruits are much appreciated and are commonly used for both culinary and medicinal purposes. The fruits are consumed in different forms (chicha, arrope, hydroalcoholic beverage and jam). Arrope is very similar to honey or plant molasses and it is used instead.1,2 The aim of the current work was to assess the antioxidant and anti-inflammatory activities of chañar fruits and to compare the HPLC pattern of the Amberlite-retained methanolic extracts (ARME) from different Chilean collections of fruits. An arrope sample was included for comparison. The samples comprised different collection places from the Copiapo and Limari valleys associated with precolumbian cultures. Large differences were found in the HPLC patterns of phenolics, allowing a differentiation of fruit samples. The antioxidant activity was measured by scavenging of the DPPH free radical and by ferric reducing antioxidant power (FRAP). The anti-inflammatory activity was assessed by the inhibition of the proinflammatory enzymes lipoxigenase (LOX), ciclooxigenases 1 and 2 (COX-1 and COX-2). At 50 µg/mL, all ARME inhibited the LOX from the beginning of the incubation, with inhibition values between 17.3 and 82.6%. Large differences were found for the activity towards COX-1 and COX-2 with values of 0-80.8% for COX-2 and 0-93.3% for COX-1. The COX-1 was not inhibited by the fruits collected in Alto del Carmen and Camino a El Tránsito. This finding is relevant considering the side effects like gastrointestinal toxicity, derived from COX-1 inhibition.
publishDate 2014
dc.date.none.fl_str_mv 2014
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Congreso
Book
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/235337
Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar"); 14th International Congress of Ethnopharmacology; VIII Simposio Internacional de Química de Productos Naturales y sus Aplicaciones; Pucon; Chile; 2014; 150-150
CONICET Digital
CONICET
url http://hdl.handle.net/11336/235337
identifier_str_mv Antioxidant and anti-inflammatory activity of Chilean Geoffroea decorticans fruits ("Chañar"); 14th International Congress of Ethnopharmacology; VIII Simposio Internacional de Química de Productos Naturales y sus Aplicaciones; Pucon; Chile; 2014; 150-150
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://bib.irb.hr/datoteka/742320.Book_of_Abstracts.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv Universidad Talca
publisher.none.fl_str_mv Universidad Talca
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
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instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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