Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections

Autores
Adur, Javier Fernando; Bianchi, Mariana; Pelegati, Vitor B.; Viale, Silvia; Izaguirre, María Fernanda; Carvalho, Hernandes Faustino; Cesar, Carlos L.; Casco, Victor Hugo
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work provides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proliferation and collagen assembly.
Fil: Adur, Javier Fernando. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina
Fil: Bianchi, Mariana. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pelegati, Vitor B.. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil
Fil: Viale, Silvia. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Fil: Izaguirre, María Fernanda. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Fil: Carvalho, Hernandes Faustino. Universidade Estadual de Campinas; Brasil
Fil: Cesar, Carlos L.. Universidade Estadual de Campinas; Brasil
Fil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Materia
NONLINEAR MICROSCOPY
NONLINEAR MULTICONTRAST
HISTOLOGICAL SECTIONS
HUMAN COLON CANCER
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/44955
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sectionsAdur, Javier FernandoBianchi, MarianaPelegati, Vitor B.Viale, SilviaIzaguirre, María FernandaCarvalho, Hernandes FaustinoCesar, Carlos L.Casco, Victor HugoNONLINEAR MICROSCOPYNONLINEAR MULTICONTRASTHISTOLOGICAL SECTIONSHUMAN COLON CANCERhttps://purl.org/becyt/ford/2.6https://purl.org/becyt/ford/2Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work provides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proliferation and collagen assembly.Fil: Adur, Javier Fernando. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; ArgentinaFil: Bianchi, Mariana. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pelegati, Vitor B.. National Institute of Science and Technology on Photonics Applied to Cell Biology; BrasilFil: Viale, Silvia. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; ArgentinaFil: Izaguirre, María Fernanda. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; ArgentinaFil: Carvalho, Hernandes Faustino. Universidade Estadual de Campinas; BrasilFil: Cesar, Carlos L.. Universidade Estadual de Campinas; BrasilFil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; ArgentinaScientific Research Publishing2014-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/44955Adur, Javier Fernando; Bianchi, Mariana; Pelegati, Vitor B.; Viale, Silvia; Izaguirre, María Fernanda; et al.; Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections; Scientific Research Publishing; Journal of Cancer Therapy; 5; 13; 11-2014; 1259-12692151-1934CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://file.scirp.org/Html/10-8902050_51447.htminfo:eu-repo/semantics/altIdentifier/doi/10.4236/jct.2014.513127info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:15:03Zoai:ri.conicet.gov.ar:11336/44955instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:15:03.586CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
title Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
spellingShingle Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
Adur, Javier Fernando
NONLINEAR MICROSCOPY
NONLINEAR MULTICONTRAST
HISTOLOGICAL SECTIONS
HUMAN COLON CANCER
title_short Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
title_full Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
title_fullStr Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
title_full_unstemmed Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
title_sort Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
dc.creator.none.fl_str_mv Adur, Javier Fernando
Bianchi, Mariana
Pelegati, Vitor B.
Viale, Silvia
Izaguirre, María Fernanda
Carvalho, Hernandes Faustino
Cesar, Carlos L.
Casco, Victor Hugo
author Adur, Javier Fernando
author_facet Adur, Javier Fernando
Bianchi, Mariana
Pelegati, Vitor B.
Viale, Silvia
Izaguirre, María Fernanda
Carvalho, Hernandes Faustino
Cesar, Carlos L.
Casco, Victor Hugo
author_role author
author2 Bianchi, Mariana
Pelegati, Vitor B.
Viale, Silvia
Izaguirre, María Fernanda
Carvalho, Hernandes Faustino
Cesar, Carlos L.
Casco, Victor Hugo
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv NONLINEAR MICROSCOPY
NONLINEAR MULTICONTRAST
HISTOLOGICAL SECTIONS
HUMAN COLON CANCER
topic NONLINEAR MICROSCOPY
NONLINEAR MULTICONTRAST
HISTOLOGICAL SECTIONS
HUMAN COLON CANCER
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.6
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work provides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proliferation and collagen assembly.
Fil: Adur, Javier Fernando. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina
Fil: Bianchi, Mariana. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pelegati, Vitor B.. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil
Fil: Viale, Silvia. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Fil: Izaguirre, María Fernanda. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Fil: Carvalho, Hernandes Faustino. Universidade Estadual de Campinas; Brasil
Fil: Cesar, Carlos L.. Universidade Estadual de Campinas; Brasil
Fil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
description Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work provides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proliferation and collagen assembly.
publishDate 2014
dc.date.none.fl_str_mv 2014-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/44955
Adur, Javier Fernando; Bianchi, Mariana; Pelegati, Vitor B.; Viale, Silvia; Izaguirre, María Fernanda; et al.; Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections; Scientific Research Publishing; Journal of Cancer Therapy; 5; 13; 11-2014; 1259-1269
2151-1934
CONICET Digital
CONICET
url http://hdl.handle.net/11336/44955
identifier_str_mv Adur, Javier Fernando; Bianchi, Mariana; Pelegati, Vitor B.; Viale, Silvia; Izaguirre, María Fernanda; et al.; Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections; Scientific Research Publishing; Journal of Cancer Therapy; 5; 13; 11-2014; 1259-1269
2151-1934
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://file.scirp.org/Html/10-8902050_51447.htm
info:eu-repo/semantics/altIdentifier/doi/10.4236/jct.2014.513127
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Scientific Research Publishing
publisher.none.fl_str_mv Scientific Research Publishing
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781578505617408
score 12.982451

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