Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections
- Autores
- Adur, Javier Fernando; Bianchi, Mariana; Pelegati, Vitor B.; Viale, Silvia; Izaguirre, María Fernanda; Carvalho, Hernandes Faustino; Cesar, Carlos L.; Casco, Victor Hugo
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work provides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proliferation and collagen assembly.
Fil: Adur, Javier Fernando. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina
Fil: Bianchi, Mariana. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pelegati, Vitor B.. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil
Fil: Viale, Silvia. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Fil: Izaguirre, María Fernanda. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina
Fil: Carvalho, Hernandes Faustino. Universidade Estadual de Campinas; Brasil
Fil: Cesar, Carlos L.. Universidade Estadual de Campinas; Brasil
Fil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina - Materia
-
NONLINEAR MICROSCOPY
NONLINEAR MULTICONTRAST
HISTOLOGICAL SECTIONS
HUMAN COLON CANCER - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/44955
Ver los metadatos del registro completo
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Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sectionsAdur, Javier FernandoBianchi, MarianaPelegati, Vitor B.Viale, SilviaIzaguirre, María FernandaCarvalho, Hernandes FaustinoCesar, Carlos L.Casco, Victor HugoNONLINEAR MICROSCOPYNONLINEAR MULTICONTRASTHISTOLOGICAL SECTIONSHUMAN COLON CANCERhttps://purl.org/becyt/ford/2.6https://purl.org/becyt/ford/2Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work provides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proliferation and collagen assembly.Fil: Adur, Javier Fernando. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; ArgentinaFil: Bianchi, Mariana. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pelegati, Vitor B.. National Institute of Science and Technology on Photonics Applied to Cell Biology; BrasilFil: Viale, Silvia. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; ArgentinaFil: Izaguirre, María Fernanda. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; ArgentinaFil: Carvalho, Hernandes Faustino. Universidade Estadual de Campinas; BrasilFil: Cesar, Carlos L.. Universidade Estadual de Campinas; BrasilFil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; ArgentinaScientific Research Publishing2014-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/44955Adur, Javier Fernando; Bianchi, Mariana; Pelegati, Vitor B.; Viale, Silvia; Izaguirre, María Fernanda; et al.; Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections; Scientific Research Publishing; Journal of Cancer Therapy; 5; 13; 11-2014; 1259-12692151-1934CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://file.scirp.org/Html/10-8902050_51447.htminfo:eu-repo/semantics/altIdentifier/doi/10.4236/jct.2014.513127info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:46:14Zoai:ri.conicet.gov.ar:11336/44955instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:46:14.524CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections |
title |
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections |
spellingShingle |
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections Adur, Javier Fernando NONLINEAR MICROSCOPY NONLINEAR MULTICONTRAST HISTOLOGICAL SECTIONS HUMAN COLON CANCER |
title_short |
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections |
title_full |
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections |
title_fullStr |
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections |
title_full_unstemmed |
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections |
title_sort |
Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections |
dc.creator.none.fl_str_mv |
Adur, Javier Fernando Bianchi, Mariana Pelegati, Vitor B. Viale, Silvia Izaguirre, María Fernanda Carvalho, Hernandes Faustino Cesar, Carlos L. Casco, Victor Hugo |
author |
Adur, Javier Fernando |
author_facet |
Adur, Javier Fernando Bianchi, Mariana Pelegati, Vitor B. Viale, Silvia Izaguirre, María Fernanda Carvalho, Hernandes Faustino Cesar, Carlos L. Casco, Victor Hugo |
author_role |
author |
author2 |
Bianchi, Mariana Pelegati, Vitor B. Viale, Silvia Izaguirre, María Fernanda Carvalho, Hernandes Faustino Cesar, Carlos L. Casco, Victor Hugo |
author2_role |
author author author author author author author |
dc.subject.none.fl_str_mv |
NONLINEAR MICROSCOPY NONLINEAR MULTICONTRAST HISTOLOGICAL SECTIONS HUMAN COLON CANCER |
topic |
NONLINEAR MICROSCOPY NONLINEAR MULTICONTRAST HISTOLOGICAL SECTIONS HUMAN COLON CANCER |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.6 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work provides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proliferation and collagen assembly. Fil: Adur, Javier Fernando. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Entre Ríos. Universidad Nacional de Entre Ríos. Centro de Investigaciones y Transferencia de Entre Ríos; Argentina Fil: Bianchi, Mariana. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Pelegati, Vitor B.. National Institute of Science and Technology on Photonics Applied to Cell Biology; Brasil Fil: Viale, Silvia. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina Fil: Izaguirre, María Fernanda. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina Fil: Carvalho, Hernandes Faustino. Universidade Estadual de Campinas; Brasil Fil: Cesar, Carlos L.. Universidade Estadual de Campinas; Brasil Fil: Casco, Victor Hugo. Universidad Nacional de Entre Ríos. Facultad de Ingeniería; Argentina |
description |
Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work provides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proliferation and collagen assembly. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-11 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/44955 Adur, Javier Fernando; Bianchi, Mariana; Pelegati, Vitor B.; Viale, Silvia; Izaguirre, María Fernanda; et al.; Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections; Scientific Research Publishing; Journal of Cancer Therapy; 5; 13; 11-2014; 1259-1269 2151-1934 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/44955 |
identifier_str_mv |
Adur, Javier Fernando; Bianchi, Mariana; Pelegati, Vitor B.; Viale, Silvia; Izaguirre, María Fernanda; et al.; Colon adenocarcinoma diagnosis in human samples by multicontrast nonlinear optical microscopy of hematoxylin and eosin stained histological sections; Scientific Research Publishing; Journal of Cancer Therapy; 5; 13; 11-2014; 1259-1269 2151-1934 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://file.scirp.org/Html/10-8902050_51447.htm info:eu-repo/semantics/altIdentifier/doi/10.4236/jct.2014.513127 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Scientific Research Publishing |
publisher.none.fl_str_mv |
Scientific Research Publishing |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613444023615488 |
score |
13.070432 |