A novel system of coils for magnetobiology research

Autores
Makinistian, Leonardo
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A novel system of coils for testing in vitro magnetobiological effects was designed, simulated, and built. Opposite to what is usual, the system generates a controlled gradient of magnetic field. This feature is introduced to allow the assessment of multiple values of the field in a single experiment. The apparatus consists of two flattened orthogonal coils, which permit independent control of two of the spatial components of the field. Geometry of design, combined with the use of a standard multi-well microplate for cellular culture, allows for simultaneous testing of 96 different field conditions. The system, intended to increase the efficiency of evaluating biological effects throughout ranges of the field parameters, was fully characterized injecting DC currents to the coils (i.e., generating static magnetic fields) in order to assess the spatial distribution of both the field's and field-gradient's components. Temperature load was carefully evaluated and the maximum values of 350 μT and 9 μT/mm (for the field and its gradient) could be generated without excessive heating of the cellular cultures.
Fil: Makinistian, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada ; Argentina. Universidad Nacional de San Luis. Facultad de Ciencias Físico- Matemáticas y Naturales; Argentina
Materia
MAGNETOBIOLOGY
SYSTEM OF COILS
INHOMOGENEOUS MAGNETIC FIELDS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/60427
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/60427
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A novel system of coils for magnetobiology researchMakinistian, LeonardoMAGNETOBIOLOGYSYSTEM OF COILSINHOMOGENEOUS MAGNETIC FIELDShttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1A novel system of coils for testing in vitro magnetobiological effects was designed, simulated, and built. Opposite to what is usual, the system generates a controlled gradient of magnetic field. This feature is introduced to allow the assessment of multiple values of the field in a single experiment. The apparatus consists of two flattened orthogonal coils, which permit independent control of two of the spatial components of the field. Geometry of design, combined with the use of a standard multi-well microplate for cellular culture, allows for simultaneous testing of 96 different field conditions. The system, intended to increase the efficiency of evaluating biological effects throughout ranges of the field parameters, was fully characterized injecting DC currents to the coils (i.e., generating static magnetic fields) in order to assess the spatial distribution of both the field's and field-gradient's components. Temperature load was carefully evaluated and the maximum values of 350 μT and 9 μT/mm (for the field and its gradient) could be generated without excessive heating of the cellular cultures.Fil: Makinistian, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada ; Argentina. Universidad Nacional de San Luis. Facultad de Ciencias Físico- Matemáticas y Naturales; ArgentinaAmerican Institute of Physics2016-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/60427Makinistian, Leonardo; A novel system of coils for magnetobiology research; American Institute of Physics; Review of Scientific Instruments; 87; 11; 11-2016; 1-9; 1143040034-6748CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1063/1.4968200info:eu-repo/semantics/altIdentifier/url/https://aip.scitation.org/doi/10.1063/1.4968200info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:37:30Zoai:ri.conicet.gov.ar:11336/60427instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:37:31.12CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A novel system of coils for magnetobiology research
title A novel system of coils for magnetobiology research
spellingShingle A novel system of coils for magnetobiology research
Makinistian, Leonardo
MAGNETOBIOLOGY
SYSTEM OF COILS
INHOMOGENEOUS MAGNETIC FIELDS
title_short A novel system of coils for magnetobiology research
title_full A novel system of coils for magnetobiology research
title_fullStr A novel system of coils for magnetobiology research
title_full_unstemmed A novel system of coils for magnetobiology research
title_sort A novel system of coils for magnetobiology research
dc.creator.none.fl_str_mv Makinistian, Leonardo
author Makinistian, Leonardo
author_facet Makinistian, Leonardo
author_role author
dc.subject.none.fl_str_mv MAGNETOBIOLOGY
SYSTEM OF COILS
INHOMOGENEOUS MAGNETIC FIELDS
topic MAGNETOBIOLOGY
SYSTEM OF COILS
INHOMOGENEOUS MAGNETIC FIELDS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A novel system of coils for testing in vitro magnetobiological effects was designed, simulated, and built. Opposite to what is usual, the system generates a controlled gradient of magnetic field. This feature is introduced to allow the assessment of multiple values of the field in a single experiment. The apparatus consists of two flattened orthogonal coils, which permit independent control of two of the spatial components of the field. Geometry of design, combined with the use of a standard multi-well microplate for cellular culture, allows for simultaneous testing of 96 different field conditions. The system, intended to increase the efficiency of evaluating biological effects throughout ranges of the field parameters, was fully characterized injecting DC currents to the coils (i.e., generating static magnetic fields) in order to assess the spatial distribution of both the field's and field-gradient's components. Temperature load was carefully evaluated and the maximum values of 350 μT and 9 μT/mm (for the field and its gradient) could be generated without excessive heating of the cellular cultures.
Fil: Makinistian, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada ; Argentina. Universidad Nacional de San Luis. Facultad de Ciencias Físico- Matemáticas y Naturales; Argentina
description A novel system of coils for testing in vitro magnetobiological effects was designed, simulated, and built. Opposite to what is usual, the system generates a controlled gradient of magnetic field. This feature is introduced to allow the assessment of multiple values of the field in a single experiment. The apparatus consists of two flattened orthogonal coils, which permit independent control of two of the spatial components of the field. Geometry of design, combined with the use of a standard multi-well microplate for cellular culture, allows for simultaneous testing of 96 different field conditions. The system, intended to increase the efficiency of evaluating biological effects throughout ranges of the field parameters, was fully characterized injecting DC currents to the coils (i.e., generating static magnetic fields) in order to assess the spatial distribution of both the field's and field-gradient's components. Temperature load was carefully evaluated and the maximum values of 350 μT and 9 μT/mm (for the field and its gradient) could be generated without excessive heating of the cellular cultures.
publishDate 2016
dc.date.none.fl_str_mv 2016-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/60427
Makinistian, Leonardo; A novel system of coils for magnetobiology research; American Institute of Physics; Review of Scientific Instruments; 87; 11; 11-2016; 1-9; 114304
0034-6748
CONICET Digital
CONICET
url http://hdl.handle.net/11336/60427
identifier_str_mv Makinistian, Leonardo; A novel system of coils for magnetobiology research; American Institute of Physics; Review of Scientific Instruments; 87; 11; 11-2016; 1-9; 114304
0034-6748
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1063/1.4968200
info:eu-repo/semantics/altIdentifier/url/https://aip.scitation.org/doi/10.1063/1.4968200
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Institute of Physics
publisher.none.fl_str_mv American Institute of Physics
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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