The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in h...

Autores
Cointry, Gustavo Roberto; Ferretti, Jose Luis; Reina, Paola Soledad; Nocciolino, Laura Marcela; Rittweger, J; Capozza, Ricardo Francisco
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The pQCT-assessed Bone Strength Indices (BSI?s, SSI) depend on the product of a ?quality? indicator, the cortical vBMD (vCtD), and a ?design? indicator, one of the cross-sectional moments of inertia or related variables (MIs) in long bones. As the MIs vary naturally much more than the vCtD and represent different properties, it could be that the variation of the indices might not reflect the relative mechanical impact of the variation of their determinant factors in different individuals or circumstances. To understand this problem, we determined the vCtD and MI?s in tibia scans of 232 healthy men and pre- and post-MP women, expressed in SD of the means calculated for each group, and analyzed the independent influence of 1 SD unit of variation of each factor on that of the indices by multiple correlations. Results showed: 1. that the independent influence of the MIs on the indices was generally larger than that of the vCtD, and 2. that in post-MP women the influence of the vCtD was larger than it was in the other groups. This confirms the view that inter-individual variation of vCtD is comparatively small, and that mechanical competence of human bone is mostly determined by ?design? factors.
Fil: Cointry, Gustavo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ferretti, Jose Luis. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Reina, Paola Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina
Fil: Nocciolino, Laura Marcela. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rittweger, J. German Aerospace Center; Alemania. Manchester Metropolitan University; Reino Unido
Fil: Capozza, Ricardo Francisco. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Bone Structure
Bone Biomechanics
Moment of Inertia
Bone Density
Bone Quality
pQCT
Bone Strenght Index
Bone Strength Evaluation
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/30907
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/30907
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal womenCointry, Gustavo RobertoFerretti, Jose LuisReina, Paola SoledadNocciolino, Laura MarcelaRittweger, JCapozza, Ricardo FranciscoBone StructureBone BiomechanicsMoment of InertiaBone DensityBone QualitypQCTBone Strenght IndexBone Strength Evaluationhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The pQCT-assessed Bone Strength Indices (BSI?s, SSI) depend on the product of a ?quality? indicator, the cortical vBMD (vCtD), and a ?design? indicator, one of the cross-sectional moments of inertia or related variables (MIs) in long bones. As the MIs vary naturally much more than the vCtD and represent different properties, it could be that the variation of the indices might not reflect the relative mechanical impact of the variation of their determinant factors in different individuals or circumstances. To understand this problem, we determined the vCtD and MI?s in tibia scans of 232 healthy men and pre- and post-MP women, expressed in SD of the means calculated for each group, and analyzed the independent influence of 1 SD unit of variation of each factor on that of the indices by multiple correlations. Results showed: 1. that the independent influence of the MIs on the indices was generally larger than that of the vCtD, and 2. that in post-MP women the influence of the vCtD was larger than it was in the other groups. This confirms the view that inter-individual variation of vCtD is comparatively small, and that mechanical competence of human bone is mostly determined by ?design? factors.Fil: Cointry, Gustavo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ferretti, Jose Luis. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Reina, Paola Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; ArgentinaFil: Nocciolino, Laura Marcela. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rittweger, J. German Aerospace Center; Alemania. Manchester Metropolitan University; Reino UnidoFil: Capozza, Ricardo Francisco. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaInternational Society of Musculoskeletal and Neuronal Interactions2014-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/30907Capozza, Ricardo Francisco; Nocciolino, Laura Marcela; Reina, Paola Soledad; Ferretti, Jose Luis; Rittweger, J; Cointry, Gustavo Roberto; et al.; The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women; International Society of Musculoskeletal and Neuronal Interactions; Journal of Musculoskeletal and Neuronal Interactions; 14; 1; 11-2014; 29-401108-7161CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.ismni.org/jmni/pdf/55/04COINTRY.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:42:17Zoai:ri.conicet.gov.ar:11336/30907instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:42:17.492CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women
title The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women
spellingShingle The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women
Cointry, Gustavo Roberto
Bone Structure
Bone Biomechanics
Moment of Inertia
Bone Density
Bone Quality
pQCT
Bone Strenght Index
Bone Strength Evaluation
title_short The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women
title_full The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women
title_fullStr The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women
title_full_unstemmed The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women
title_sort The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women
dc.creator.none.fl_str_mv Cointry, Gustavo Roberto
Ferretti, Jose Luis
Reina, Paola Soledad
Nocciolino, Laura Marcela
Rittweger, J
Capozza, Ricardo Francisco
author Cointry, Gustavo Roberto
author_facet Cointry, Gustavo Roberto
Ferretti, Jose Luis
Reina, Paola Soledad
Nocciolino, Laura Marcela
Rittweger, J
Capozza, Ricardo Francisco
author_role author
author2 Ferretti, Jose Luis
Reina, Paola Soledad
Nocciolino, Laura Marcela
Rittweger, J
Capozza, Ricardo Francisco
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Bone Structure
Bone Biomechanics
Moment of Inertia
Bone Density
Bone Quality
pQCT
Bone Strenght Index
Bone Strength Evaluation
topic Bone Structure
Bone Biomechanics
Moment of Inertia
Bone Density
Bone Quality
pQCT
Bone Strenght Index
Bone Strength Evaluation
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The pQCT-assessed Bone Strength Indices (BSI?s, SSI) depend on the product of a ?quality? indicator, the cortical vBMD (vCtD), and a ?design? indicator, one of the cross-sectional moments of inertia or related variables (MIs) in long bones. As the MIs vary naturally much more than the vCtD and represent different properties, it could be that the variation of the indices might not reflect the relative mechanical impact of the variation of their determinant factors in different individuals or circumstances. To understand this problem, we determined the vCtD and MI?s in tibia scans of 232 healthy men and pre- and post-MP women, expressed in SD of the means calculated for each group, and analyzed the independent influence of 1 SD unit of variation of each factor on that of the indices by multiple correlations. Results showed: 1. that the independent influence of the MIs on the indices was generally larger than that of the vCtD, and 2. that in post-MP women the influence of the vCtD was larger than it was in the other groups. This confirms the view that inter-individual variation of vCtD is comparatively small, and that mechanical competence of human bone is mostly determined by ?design? factors.
Fil: Cointry, Gustavo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ferretti, Jose Luis. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Reina, Paola Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina
Fil: Nocciolino, Laura Marcela. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rittweger, J. German Aerospace Center; Alemania. Manchester Metropolitan University; Reino Unido
Fil: Capozza, Ricardo Francisco. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description The pQCT-assessed Bone Strength Indices (BSI?s, SSI) depend on the product of a ?quality? indicator, the cortical vBMD (vCtD), and a ?design? indicator, one of the cross-sectional moments of inertia or related variables (MIs) in long bones. As the MIs vary naturally much more than the vCtD and represent different properties, it could be that the variation of the indices might not reflect the relative mechanical impact of the variation of their determinant factors in different individuals or circumstances. To understand this problem, we determined the vCtD and MI?s in tibia scans of 232 healthy men and pre- and post-MP women, expressed in SD of the means calculated for each group, and analyzed the independent influence of 1 SD unit of variation of each factor on that of the indices by multiple correlations. Results showed: 1. that the independent influence of the MIs on the indices was generally larger than that of the vCtD, and 2. that in post-MP women the influence of the vCtD was larger than it was in the other groups. This confirms the view that inter-individual variation of vCtD is comparatively small, and that mechanical competence of human bone is mostly determined by ?design? factors.
publishDate 2014
dc.date.none.fl_str_mv 2014-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/30907
Capozza, Ricardo Francisco; Nocciolino, Laura Marcela; Reina, Paola Soledad; Ferretti, Jose Luis; Rittweger, J; Cointry, Gustavo Roberto; et al.; The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women; International Society of Musculoskeletal and Neuronal Interactions; Journal of Musculoskeletal and Neuronal Interactions; 14; 1; 11-2014; 29-40
1108-7161
CONICET Digital
CONICET
url http://hdl.handle.net/11336/30907
identifier_str_mv Capozza, Ricardo Francisco; Nocciolino, Laura Marcela; Reina, Paola Soledad; Ferretti, Jose Luis; Rittweger, J; Cointry, Gustavo Roberto; et al.; The pQCT “Bone Strength Indices” (BSIs, SSI). Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women; International Society of Musculoskeletal and Neuronal Interactions; Journal of Musculoskeletal and Neuronal Interactions; 14; 1; 11-2014; 29-40
1108-7161
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ismni.org/jmni/pdf/55/04COINTRY.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv International Society of Musculoskeletal and Neuronal Interactions
publisher.none.fl_str_mv International Society of Musculoskeletal and Neuronal Interactions
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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