pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women

Autores
Capozza, Ricardo Francisco; Rittweger, J.; Reina, Paola Soledad; Mortarino, P.; Nocciolino, Laura Marcela; Feldman, Sara; Ferretti, Jose Luis; Cointry, Gustavo Roberto
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In a pQCT study of running-trained and untrained men and women we had shown that bone mass distribution along the tibia was adapted to the usage-derived stress pattern. To study the possible association between the efficiency of diaphyseal design and bone material stiffness, we extend the analysis of the same sample to correlate pQCT indicators of the distribution (CSMIs), mass (BMC), and density (vBMD) of cortical bone tissue as descriptors of “distribution/mass” (d/m) or “distribution/quality” (d/q) relationships. The d/m and d/c curves followed positive (exponential) and negative (hyperbolic-like) equations, respectively. Distribution curves of r coefficients throughout the bone were all bell-shaped, reaching a maximum towards the mid-diaphysis. The CSMIs and BMC were higher, and vBMD was lower in men than women and in runners than non-runners. The d/m relationships were described by unique curves for all groups while d/q relationships were better adjusted to separate curves for men and women. Results support that: 1. diaphyseal design reflects the relative influence of bending/torsion stress along the bones, tending to minimize bone mass; 2. there is a trade-off between cortical bone “quality” and distribution; 3. d/m and d/q relationships are related to bone mechanical environment, and 4. d/q relationships are affected by sex.
Fil: Capozza, Ricardo Francisco. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rittweger, J.. German Aerospace Center ; Alemania
Fil: Reina, Paola Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Mortarino, P.. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina
Fil: Nocciolino, Laura Marcela. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Feldman, Sara. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Osteoarticular, Ingeniería Tisular y Terapias Emergentes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ferretti, Jose Luis. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Cointry, Gustavo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Bone Biomechanics
pQCT
Osteoporosis
Bone Density
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/22579
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and womenCapozza, Ricardo FranciscoRittweger, J.Reina, Paola SoledadMortarino, P.Nocciolino, Laura MarcelaFeldman, SaraFerretti, Jose LuisCointry, Gustavo RobertoBone BiomechanicspQCTOsteoporosisBone Densityhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3In a pQCT study of running-trained and untrained men and women we had shown that bone mass distribution along the tibia was adapted to the usage-derived stress pattern. To study the possible association between the efficiency of diaphyseal design and bone material stiffness, we extend the analysis of the same sample to correlate pQCT indicators of the distribution (CSMIs), mass (BMC), and density (vBMD) of cortical bone tissue as descriptors of “distribution/mass” (d/m) or “distribution/quality” (d/q) relationships. The d/m and d/c curves followed positive (exponential) and negative (hyperbolic-like) equations, respectively. Distribution curves of r coefficients throughout the bone were all bell-shaped, reaching a maximum towards the mid-diaphysis. The CSMIs and BMC were higher, and vBMD was lower in men than women and in runners than non-runners. The d/m relationships were described by unique curves for all groups while d/q relationships were better adjusted to separate curves for men and women. Results support that: 1. diaphyseal design reflects the relative influence of bending/torsion stress along the bones, tending to minimize bone mass; 2. there is a trade-off between cortical bone “quality” and distribution; 3. d/m and d/q relationships are related to bone mechanical environment, and 4. d/q relationships are affected by sex.Fil: Capozza, Ricardo Francisco. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rittweger, J.. German Aerospace Center ; AlemaniaFil: Reina, Paola Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Mortarino, P.. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; ArgentinaFil: Nocciolino, Laura Marcela. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Feldman, Sara. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Osteoarticular, Ingeniería Tisular y Terapias Emergentes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ferretti, Jose Luis. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Cointry, Gustavo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaHylonome Publications2013-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/22579Capozza, Ricardo Francisco; Rittweger, J.; Reina, Paola Soledad; Mortarino, P.; Nocciolino, Laura Marcela; et al.; pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women; Hylonome Publications; Journal of Musculoskeletal & Neuronal Interactions; 13; 2; 6-2013; 195-2051108-7161CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.ismni.org/jmni/Archive.php?year=2013#v13i2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:21:19Zoai:ri.conicet.gov.ar:11336/22579instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:21:20.032CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women
title pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women
spellingShingle pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women
Capozza, Ricardo Francisco
Bone Biomechanics
pQCT
Osteoporosis
Bone Density
title_short pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women
title_full pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women
title_fullStr pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women
title_full_unstemmed pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women
title_sort pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women
dc.creator.none.fl_str_mv Capozza, Ricardo Francisco
Rittweger, J.
Reina, Paola Soledad
Mortarino, P.
Nocciolino, Laura Marcela
Feldman, Sara
Ferretti, Jose Luis
Cointry, Gustavo Roberto
author Capozza, Ricardo Francisco
author_facet Capozza, Ricardo Francisco
Rittweger, J.
Reina, Paola Soledad
Mortarino, P.
Nocciolino, Laura Marcela
Feldman, Sara
Ferretti, Jose Luis
Cointry, Gustavo Roberto
author_role author
author2 Rittweger, J.
Reina, Paola Soledad
Mortarino, P.
Nocciolino, Laura Marcela
Feldman, Sara
Ferretti, Jose Luis
Cointry, Gustavo Roberto
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Bone Biomechanics
pQCT
Osteoporosis
Bone Density
topic Bone Biomechanics
pQCT
Osteoporosis
Bone Density
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv In a pQCT study of running-trained and untrained men and women we had shown that bone mass distribution along the tibia was adapted to the usage-derived stress pattern. To study the possible association between the efficiency of diaphyseal design and bone material stiffness, we extend the analysis of the same sample to correlate pQCT indicators of the distribution (CSMIs), mass (BMC), and density (vBMD) of cortical bone tissue as descriptors of “distribution/mass” (d/m) or “distribution/quality” (d/q) relationships. The d/m and d/c curves followed positive (exponential) and negative (hyperbolic-like) equations, respectively. Distribution curves of r coefficients throughout the bone were all bell-shaped, reaching a maximum towards the mid-diaphysis. The CSMIs and BMC were higher, and vBMD was lower in men than women and in runners than non-runners. The d/m relationships were described by unique curves for all groups while d/q relationships were better adjusted to separate curves for men and women. Results support that: 1. diaphyseal design reflects the relative influence of bending/torsion stress along the bones, tending to minimize bone mass; 2. there is a trade-off between cortical bone “quality” and distribution; 3. d/m and d/q relationships are related to bone mechanical environment, and 4. d/q relationships are affected by sex.
Fil: Capozza, Ricardo Francisco. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rittweger, J.. German Aerospace Center ; Alemania
Fil: Reina, Paola Soledad. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Mortarino, P.. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina
Fil: Nocciolino, Laura Marcela. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Feldman, Sara. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Osteoarticular, Ingeniería Tisular y Terapias Emergentes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ferretti, Jose Luis. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Cointry, Gustavo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description In a pQCT study of running-trained and untrained men and women we had shown that bone mass distribution along the tibia was adapted to the usage-derived stress pattern. To study the possible association between the efficiency of diaphyseal design and bone material stiffness, we extend the analysis of the same sample to correlate pQCT indicators of the distribution (CSMIs), mass (BMC), and density (vBMD) of cortical bone tissue as descriptors of “distribution/mass” (d/m) or “distribution/quality” (d/q) relationships. The d/m and d/c curves followed positive (exponential) and negative (hyperbolic-like) equations, respectively. Distribution curves of r coefficients throughout the bone were all bell-shaped, reaching a maximum towards the mid-diaphysis. The CSMIs and BMC were higher, and vBMD was lower in men than women and in runners than non-runners. The d/m relationships were described by unique curves for all groups while d/q relationships were better adjusted to separate curves for men and women. Results support that: 1. diaphyseal design reflects the relative influence of bending/torsion stress along the bones, tending to minimize bone mass; 2. there is a trade-off between cortical bone “quality” and distribution; 3. d/m and d/q relationships are related to bone mechanical environment, and 4. d/q relationships are affected by sex.
publishDate 2013
dc.date.none.fl_str_mv 2013-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/22579
Capozza, Ricardo Francisco; Rittweger, J.; Reina, Paola Soledad; Mortarino, P.; Nocciolino, Laura Marcela; et al.; pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women; Hylonome Publications; Journal of Musculoskeletal & Neuronal Interactions; 13; 2; 6-2013; 195-205
1108-7161
CONICET Digital
CONICET
url http://hdl.handle.net/11336/22579
identifier_str_mv Capozza, Ricardo Francisco; Rittweger, J.; Reina, Paola Soledad; Mortarino, P.; Nocciolino, Laura Marcela; et al.; pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women; Hylonome Publications; Journal of Musculoskeletal & Neuronal Interactions; 13; 2; 6-2013; 195-205
1108-7161
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ismni.org/jmni/Archive.php?year=2013#v13i2
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hylonome Publications
publisher.none.fl_str_mv Hylonome Publications
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.069144

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